BCAR3 (NM_003567) Human Tagged ORF Clone
CAT#: RC207930L1
- LentiORF®
Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), Myc-DDK-tagged
"NM_003567" in other vectors (7)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | BCAR3 |
Synonyms | AND-34; MIG7; NSP2; SH2D3B |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207930).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_003567 |
ORF Size | 2475 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_003567.2 |
RefSeq Size | 3203 bp |
RefSeq ORF | 2478 bp |
Locus ID | 8412 |
UniProt ID | O75815 |
Cytogenetics | 1p22.1 |
Domains | SH2, RasGEF |
Protein Families | Druggable Genome |
MW | 92.6 kDa |
Gene Summary | Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC125362 | BCAR3 (untagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3) |
USD 310.00 |
|
SC324095 | BCAR3 (untagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3) |
USD 310.00 |
|
RC207930 | BCAR3 (Myc-DDK-tagged)-Human breast cancer anti-estrogen resistance 3 (BCAR3) |
USD 610.00 |
|
RG207930 | BCAR3 (GFP-tagged) - Human breast cancer anti-estrogen resistance 3 (BCAR3) |
USD 670.00 |
|
RC207930L2 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), mGFP tagged |
USD 810.00 |
|
RC207930L3 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), Myc-DDK-tagged |
USD 810.00 |
|
RC207930L4 | Lenti ORF clone of Human breast cancer anti-estrogen resistance 3 (BCAR3), mGFP tagged |
USD 810.00 |
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