Cullin 3 (CUL3) (NM_003590) Human Tagged ORF Clone
CAT#: RC208066L4
- LentiORF®
Lenti ORF clone of Human cullin 3 (CUL3), mGFP tagged
"NM_003590" in other vectors (7)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | CUL3 |
Synonyms | CUL-3; PHA2E |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208066).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_003590 |
ORF Size | 2304 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_003590.2, NP_003581.1 |
RefSeq Size | 6790 bp |
RefSeq ORF | 2307 bp |
Locus ID | 8452 |
UniProt ID | Q13618, A0A024R475 |
Cytogenetics | 2q36.2 |
Domains | CULLIN |
Protein Families | Druggable Genome |
Protein Pathways | Ubiquitin mediated proteolysis |
MW | 88.9 kDa |
Gene Summary | This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC117870 | CUL3 (untagged)-Human cullin 3 (CUL3) |
USD 310.00 |
|
SC322625 | CUL3 (untagged)-Human cullin 3 (CUL3) |
USD 310.00 |
|
RC208066 | CUL3 (Myc-DDK-tagged)-Human cullin 3 (CUL3) |
USD 420.00 |
|
RG208066 | CUL3 (GFP-tagged) - Human cullin 3 (CUL3) |
USD 460.00 |
|
RC208066L1 | Lenti ORF clone of Human cullin 3 (CUL3), Myc-DDK-tagged |
USD 768.00 |
|
RC208066L2 | Lenti ORF clone of Human cullin 3 (CUL3), mGFP tagged |
USD 620.00 |
|
RC208066L3 | Lenti ORF clone of Human cullin 3 (CUL3), Myc-DDK-tagged |
USD 620.00 |
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