AP3B2 (NM_004644) Human Tagged ORF Clone

CAT#: RC210820L2

Lenti ORF clone of Human adaptor-related protein complex 3, beta 2 subunit (AP3B2), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: AP3B2
• Synonyms: EIEE48; NAPTB
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210820).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_004644
• ORF Size: 3246 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004644.3, NP_004635.2
• RefSeq Size: 3771
• RefSeq ORF: 3249
• Locus ID: 8120
• Domains: Adaptin_N
• Protein Pathways: Lysosome
• MW: 119.1 kDa
• Gene Summary: Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]