SPIRE1 (NM_020148) Human Tagged ORF Clone

CAT#: RC213848L3

Lenti ORF clone of Human spire homolog 1 (Drosophila) (SPIRE1), transcript variant 2, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SPIRE1
• Synonyms: Spir-1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213848).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_020148
• ORF Size: 1749 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020148.2, NP_064533.1
• RefSeq Size: 5402
• RefSeq ORF: 2229
• Locus ID: 56907
• Protein Pathways: Dorso-ventral axis formation
• MW: 67.1 kDa
• Gene Summary: Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]). [supplied by OMIM, Mar 2008]