LAT2 (SLC7A8) (NM_182728) Human Tagged ORF Clone
CAT#: RC216468L4
- LentiORF®
Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 2, mGFP tagged
"NM_182728" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | SLC7A8 |
Synonyms | LAT2; LPI-PC1 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC216468).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_182728 |
ORF Size | 1608 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_182728.1 |
RefSeq Size | 3195 |
RefSeq ORF | 999 |
Locus ID | 23428 |
Protein Families | Druggable Genome, Transmembrane |
MW | 58.4 kDa |
Gene Summary | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. [UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC107507 | SLC7A8 (untagged)-Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 2 |
USD 660.00 |
|
RC216468 | SLC7A8 (Myc-DDK-tagged)-Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 2 |
USD 420.00 |
|
RG216468 | SLC7A8 (GFP-tagged) - Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 2 |
USD 460.00 |
|
RC216468L3 | Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 2, Myc-DDK-tagged |
USD 620.00 |
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