KCNQ3 (NM_004519) Human Tagged ORF Clone
CAT#: RC218739L1
- LentiORF®
Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, Myc-DDK-tagged
"NM_004519" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | KCNQ3 |
Synonyms | BFNC2; EBN2; KV7.3 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218739).
|
Restriction Sites | SgfI-XhoI Cloning Scheme for this gene |
ACCN | NM_004519 |
ORF Size | 2616 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_004519.2, NP_004510.1 |
RefSeq Size | 3097 bp |
RefSeq ORF | 2619 bp |
Locus ID | 3786 |
UniProt ID | O43525 |
Cytogenetics | 8q24.22 |
Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
MW | 96.6 kDa |
Gene Summary | This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303492 | KCNQ3 (untagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1 |
USD 1,770.00 |
|
RC218739 | KCNQ3 (Myc-DDK-tagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1 |
USD 970.00 |
|
RG218739 | KCNQ3 (GFP-tagged) - Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1 |
USD 1,070.00 |
|
RC218739L2 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, mGFP tagged |
USD 1,170.00 |
|
RC218739L3 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, Myc-DDK-tagged |
USD 1,170.00 |
|
RC218739L4 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, mGFP tagged |
USD 1,170.00 |
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