PTPN22 (NM_015967) Human Tagged ORF Clone
CAT#: RC218969L2
- LentiORF®
Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1, mGFP tagged
"NM_015967" in other vectors (6)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | PTPN22 |
Synonyms | LYP; LYP1; LYP2; PEP; PTPN8; PTPN22.5; PTPN22.6 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218969).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_015967 |
ORF Size | 2421 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_015967.3, NP_057051.2 |
RefSeq Size | 3615 |
RefSeq ORF | 2424 |
Locus ID | 26191 |
Domains | Y_phosphatase, PTPc_motif |
Protein Families | Druggable Genome, Phosphatase |
MW | 91.5 kDa |
Gene Summary | This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC114550 | PTPN22 (untagged)-Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1 |
USD 1,630.00 |
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RC218969 | PTPN22 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1 |
USD 610.00 |
|
RG218969 | PTPN22 (GFP-tagged) - Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1 |
USD 670.00 |
|
RC218969L1 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1, Myc-DDK-tagged |
USD 1,008.00 |
|
RC218969L3 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1, Myc-DDK-tagged |
USD 810.00 |
|
RC218969L4 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1, mGFP tagged |
USD 810.00 |
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