PTPN22 (NM_015967) Human Untagged Clone

CAT#: SC114550

PTPN22 (untagged)-Human protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN22
• Synonyms: LYP; LYP1; LYP2; PEP; PTPN8; PTPN22.5; PTPN22.6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015967, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCAAAGAGAAATTCTGCAGAAGTTCCTGGATGAGGCCCAAAGCAAGAAAATTACTAAAGAGGAGT
  TTGCCAATGAATTTCTGAAGCTGAAAAGGCAATCTACCAAGTACAAGGCAGACAAAACCTATCCTACAAC
  TGTGGCTGAGAAGCCCAAGAATATCAAGAAAAACAGATATAAGGATATTTTGCCCTATGATTATAGCCGG
  GTAGAACTATCCCTGATAACCTCTGATGAGGATTCCAGCTACATCAATGCCAACTTCATTAAGGGAGTTT
  ATGGACCCAAGGCTTATATTGCCACCCAGGGTCCTTTATCTACAACCCTCCTGGACTTCTGGAGGATGAT
  TTGGGAATATAGTGTCCTTATCATTGTTATGGCATGCATGGAGTATGAAATGGGAAAGAAAAAGTGTGAG
  CGCTACTGGGCTGAGCCAGGAGAGATGCAGCTGGAATTTGGCCCTTTCTCTGTATCCTGTGAAGCTGAAA
  AAAGGAAATCTGATTATATAATCAGGACTCTAAAAGTTAAGTTCAATAGTGAAACTCGAACTATCTACCA
  GTTTCATTACAAGAATTGGCCAGACCATGATGTACCTTCATCTATAGACCCTATTCTTGAGCTCATCTGG
  GATGTACGTTGTTACCAAGAGGATGACAGTGTTCCCATATGCATTCACTGCAGTGCTGGCTGTGGAAGGA
  CTGGTGTTATTTGTGCTATTGATTATACATGGATGTTGCTAAAAGATGGGATAATTCCTGAGAACTTCAG
  TGTTTTCAGTTTGATCCGGGAAATGCGGACACAGAGGCCTTCATTAGTTCAAACGCAGGAACAATATGAA
  CTGGTCTACAATGCTGTATTAGAACTATTTAAGAGACAGATGGATGTTATCAGAGATAAACATTCTGGAA
  CAGAGAGTCAAGCAAAGCATTGTATTCCTGAGAAAAATCACACTCTCCAAGCAGACTCTTATTCTCCTAA
  TTTACCAAAAAGTACCACAAAAGCAGCAAAAATGATGAACCAACAAAGGACAAAAATGGAAATCAAAGAA
  TCTTCTTCCTTTGACTTTAGGACTTCTGAAATAAGTGCAAAAGAAGAGCTAGTTTTGCACCCTGCTAAAT
  CAAGCACTTCTTTTGACTTTCTGGAGCTAAATTACAGTTTTGACAAAAATGCTGACACAACCATGAAATG
  GCAGACAAAGGCATTTCCAATAGTTGGGGAGCCTCTTCAGAAGCATCAAAGTTTGGATTTGGGCTCTCTT
  TTGTTTGAGGGATGTTCTAATTCTAAACCTGTAAATGCAGCAGGAAGATATTTTAATTCAAAGGTGCCAA
  TAACACGGACCAAATCAACTCCTTTTGAATTGATACAGCAGAGAGAAACCAAGGAGGTGGACAGCAAGGA
  AAACTTTTCTTATTTGGAATCTCAACCACATGATTCTTGTTTTGTAGAGATGCAGGCTCAAAAAGTAATG
  CATGTTTCTTCAGCAGAACTGAATTATTCACTGCCATATGACTCTAAACACCAAATACGTAATGCCTCTA
  ATGTAAAGCACCATGACTCTAGTGCTCTTGGTGTATATTCTTACATACCTTTAGTGGAAAATCCTTATTT
  TTCATCATGGCCTCCAAGTGGTACCAGTTCTAAGATGTCTCTTGATTTACCTGAGAAGCAAGATGGAACT
  GTTTTTCCTTCTTCTCTGTTGCCAACATCCTCTACATCCCTCTTCTCTTATTACAATTCACATGATTCTT
  TATCACTGAATTCTCCAACCAATATTTCCTCACTATTGAACCAGGAGTCAGCTGTACTAGCAACTGCTCC
  AAGGATAGATGATGAAATCCCCCCTCCACTTCCTGTACGGACACCTGAATCATTTATTGTGGTTGAGGAA
  GCTGGAGAATTCTCACCAAATGTTCCCAAATCCTTATCCTCAGCTGTGAAGGTAAAAATTGGAACATCAC
  TGGAATGGGGTGGAACATCTGAACCAAAGAAATTTGATGACTCTGTGATACTTAGACCAAGCAAGAGTGT
  AAAACTCCGAAGTCCTAAATCAGAACTACATCAAGATCGTTCTTCTCCCCCACCTCCTCTCCCAGAAAGA
  ACTCTAGAGTCCTTCTTTCTTGCCGATGAAGATTGTATGCAGGCCCAATCTATAGAAACATATTCTACTA
  GCTATCCTGACACCATGGAAAATTCAACATCTTCAAAACAGACACTGAAGACTCCTGGAAAAAGTTTCAC
  AAGGAGTAAGAGTTTGAAAATTTTGCGAAACATGAAAAAGAGTATCTGTAATTCTTGCCCACCAAACAAG
  CCTGCAGAATCTGTTCAGTCAAATAACTCCAGCTCATTTCTGAATTTTGGTTTTGCAAACCGTTTTTCAA
  AACCCAAAGGACCAAGGAATCCACCACCAACTTGGAATATTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015967 unedited
  CGGAAAACCCAATTCGCACCAGCGGCAGCAGTGGCTTTTTGGAGGTGTCTCGGCCATGAC
  ACACATTTGACATGCCCTCCCTCAACCTACTTATAGACTATTTTTCTTGCTCTGCAGCAT
  GGACCAAAGAGAAATTCTGCAGAAGTTCCTGGATGAGGCCCAAAGCAAGAAAATTACTAA
  AGATTTGTTTGCCAATGAATTTCTGAAGCTGAAAAGGCAATCTACCAAGTACAAGGCAGA
  CAAAACCTATCCTACAACTGTGGCTGAGAAGCCCAAGAATATCAAGAAAAACAGATATAA
  GGATATTTTGCCCTATGATTATAGCCGGGTAGAACTATCCCTGATAACCTCTGATGAGGA
  TTCCAGCTACATCAATGCCAACTTCATTAAGGGAGTTTATGGACCCAAGGCTTATATTGC
  CACCCAGGGTCCTTTATCTACAACCCTCCTGGACTTCTGGAGGATGATTTGGGAATATAG
  TGTCCTTATCATTGTTATGGCATGCATGGAGTATGAAATGGGAAAGAAAAAGTGTGAGCG
  CTACTGGGCTGAGCCAGGAGAGATGCAGCTGGAATTTGGCCCTTTCTCTGTATCCTGTGA
  AGCTGAAAAAAGGAAATCTGATTATATAATCAGGACTCTAAAAGTTAAGTTCAATAGTGA
  AACTCGAACTATCTACCAGTTTCATTACAAGAATTGGCCAGACCATGATGTACCTTCATC
  TATAGACCCTATTCTTGAGCTCATCTGGGATGTACGTTGTTACCAAGAGGATGACAGTGT
  TCCCATATGCATTCACTGCAGTGCTGGCTGTGGAAGGACTGGGTGTAATTGTGCTATTGA
  TATACATGGNNATGTGCTAAAGATGGATAATTCCTGAGAACTTCAGTGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015967 unedited
  GGGGGAGGGAAACANNAATANTTTANANNNANNTTTTACTTGNACCCGGCCGCAATCTAN
  GATCGGTTTTTTTTTTTTTTTGTTTTTTTTTTTTAACAACCAAAAATTTATTGAGTGTCT
  GTTGGATACATTGTACTACAAGAGACAGATAATAATACTTCATTCAATTTGCCCTATTGG
  ACTTCCAAATGAAAAATACTGAAGAACAAATGATGTTTAAACAATACTACATGTTTCTAA
  AAGTTATAAATAAAGTTATTTAAATAAAAATATTTTTAATGCATTAGGGGAAGTCAGGTG
  GATTCTTTGTAAAAACGATTACCTGCCAATTTATTTACTACATAAAATTAGAGTTGAACT
  AGATTTTCTTATGGCAGATCCATATTCATATAGAAATTCATTTTAAACTAGTATTTCTGA
  TTGGTTAGATAAAAATTGCACATGATCTGAAAGATCCTGTATAAACATATACAATTTATA
  TCTTTTGCTACCAAAAGATAGCTATTATATTTCATTGATTACTTTTCTAGAATTGGTAAT
  TTAATGACTTTGGTTAAAACTTATCAGGATTTCAGTTGAATTCCTTGTTACATTCAAATA
  ATTGTCATTATTTGCACATTTTATTCTAATAAATATAATTTCTCATTTTCTTAATATTCC
  AGTTTTCCACAACATTTGGGAAGATTTACAAGGTATACTCCATTTAGGCAAAAATAACTG
  TCAGGGAATAGTCATTGCCAAGAGCAGTTTGTATTGCAACCCACAAAGTAAGTTTTTTTT
  TTAACTTTTTATAGTATATTCTGGCAATGTAAAAAATAGTTTGAGATCCAAATTTACAAA
  CTTTTTGAAGTTTATGTTTTTGTTAAAAAGTAAAAGATATAAAAATACCTGGAAAAATGG
  AAAAAAATCCATTCTAAAAGGGTTTCTCTATAACATCCTGTACATAGCCCAAGTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015967
• ORF Size: 2424 bp
• Insert Size: 3600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015967.3, NP_057051.2
• RefSeq Size: 3615
• RefSeq ORF: 2424
• Locus ID: 26191
• Domains: Y_phosphatase, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note:.