gamma Sarcoglycan (SGCG) (NM_000231) Human Tagged ORF Clone
CAT#: RC220093L4
- LentiORF®
Lenti ORF clone of Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), mGFP tagged
"NM_000231" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | SGCG |
Synonyms | 35DAG; A4; DAGA4; DMDA; DMDA1; gamma-SG; LGMD2C; LGMDR5; MAM; SCARMD2; SCG3 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220093).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_000231 |
ORF Size | 873 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000231.1, NP_000222.1 |
RefSeq Size | 1661 bp |
RefSeq ORF | 876 bp |
Locus ID | 6445 |
Cytogenetics | 13q12.12 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
MW | 32.4 kDa |
Gene Summary | 'This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC300030 | SGCG (untagged)-Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) |
USD 660.00 |
|
RC220093 | SGCG (Myc-DDK-tagged)-Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) |
USD 420.00 |
|
RG220093 | SGCG (GFP-tagged) - Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) |
USD 460.00 |
|
RC220093L3 | Lenti ORF clone of Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), Myc-DDK-tagged |
USD 620.00 |
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