KDM4C (NM_001146695) Human Tagged ORF Clone

CAT#: RC228587L3

Lenti-ORF clone of KDM4C (Myc-DDK-tagged)-Human lysine (K)-specific demethylase 4C (KDM4C), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: KDM4C
• Synonyms: GASC1; JHDM3C; JMJD2C; TDRD14C
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC228587).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001146695
• ORF Size: 2439 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001146695.1, NP_001140167.1
• RefSeq ORF: 2442
• Locus ID: 23081
• Protein Families: Druggable Genome, Transcription Factors
• MW: 91.7 kDa
• Gene Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]