ZIC4 (NM_001168379) Human Tagged ORF Clone

CAT#: RC229955

ZIC4 (Myc-DDK-tagged)-Human Zic family member 4 (ZIC4), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ZIC4
• Synonyms: FLJ42609; FLJ45833
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC229955 representing NM_001168379
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAATGGCCCATGTCAAAGTCTTAGGAAAGCGGAGGGGCTTTTGGAGGGTTGCACTTCGGCCGTCACCG
  TCTTCAGGAAACTCCCTTTGGATTCCAAGGCTCAAAGTCAGAAAATGAGATACAAGACATCCTTGGTGAT
  GAGGAAACGATTACGGCTTTACCGAAACACTCTTAAAGAGTCAAGTAGCAGCTCTGGACACCATGGCCCC
  CAGCTCACCGCCGCCTCCAGCCCCTCGGTGTTCCCGGGCCTCCACGAGGAGCCTCCCCAGGCCTCCCCCA
  GCCGTCCTTTGAATGGACTCCTGCGTCTGGGGCTCCCTGGAGACATGTACGCGCGGCCGGAGCCCTTCCC
  GCCAGGGCCTGCGGCCCGCAGCGACGCCCTGGCAGCTGCCGCAGCCCTGCATGGCTACGGGGGCATGAAC
  CTGACGGTGAACCTCGCTGCGCCCCACGGTCCTGGCGCTTTCTTCCGCTACATGCGCCAGCCCATCAAAC
  AGGAGCTCATCTGCAAGTGGCTGGCGGCCGACGGCACCGCGACCCCGAGCCTCTGCTCCAAAACTTTCAG
  CACCATGCACGAGCTGGTCACGCACGTCACCGTGGAGCACGTCGGCGGCCCGGAACAGGCCAACCACATT
  TGCTTCTGGGAGGAGTGTCCGCGCCAGGGAAAGCCCTTCAAAGCCAAATACAAACTTGTAAATCACATCC
  GCGTGCACACGGGCGAGAAGCCCTTCCCTTGTCCTTTCCCGGGGTGTGGGAAGGTCTTTGCTAGATCAGA
  AAATCTCAAAATACACAAACGAACTCACACAGGCGAGAAGCCCTTCAGATGCGAGTTCGAGGGCTGCGAG
  CGGCGCTTCGCCAACAGCAGCGACCGTAAGAAGCATTCGCACGTGCACACTAGCGACAAGCCATACACGT
  GCAAGGTGCGGGGCTGCGACAAGTGCTACACGCACCCCAGCTCGCTGCGTAAGCACATGAAGGTGCACGG
  GCGCTCGCCGCCGCCCAGCTCTGGCTACGATTCGGCTACACCGTCTGCCCTCGTGTCGCCCTCGTCGGAC
  TGCGGCCACAAGTCCCAGGTGGCCTCCTCGGCGGCGGTGGCGGCGCGTACCGCCGACTTGAGCGAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC229955 representing NM_001168379
  Red=Cloning site Green=Tags(s)
  
  MNGPCQSLRKAEGLLEGCTSAVTVFRKLPLDSKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGP
  QLTAASSPSVFPGLHEEPPQASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMN
  LTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHI
  CFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCE
  RRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSPPPSSGYDSATPSALVSPSSD
  CGHKSQVASSAAVAARTADLSE
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001168379
• ORF Size: 1116 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168379.1, NP_001161851.1
• RefSeq ORF: 1119
• Locus ID: 84107
• MW: 41.1 kDa
• Gene Summary: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009]