KLHL13 (NM_001168301) Human Tagged ORF Clone

CAT#: RC230380L4

Lenti-ORF clone of KLHL13 (mGFP-tagged)-Human kelch-like 13 (Drosophila) (KLHL13), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: KLHL13
• Synonyms: BKLHD2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC230380).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001168301
• ORF Size: 1917 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001168301.1, NP_001161773.1
• RefSeq ORF: 1920
• Locus ID: 90293
• Protein Pathways: Ubiquitin mediated proteolysis
• MW: 72.6 kDa
• Gene Summary: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]