KCNQ3 (NM_001204824) Human Tagged ORF Clone
CAT#: RC234832
- TrueORF®
KCNQ3 (Myc-DDK tagged) - Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 2
"NM_001204824" in other vectors (2)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | KCNQ3 |
Synonyms | BFNC2; EBN2; KV7.3 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC234832 representing NM_001204824
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGCCTGCAGAACACGCCACGATGTTCCTGATTGTCCTGGGGTGCTTGATTCTGGCTGTCCTGACCA CATTCAAGGAGTATGAGACTGTCTCGGGAGACTGGCTTCTGTTACTGGAGACATTTGCTATTTTCATCTT TGGAGCCGAGTTTGCTTTGAGGATCTGGGCTGCTGGATGTTGCTGCCGATACAAAGGCTGGCGGGGCCGA CTGAAGTTTGCCAGGAAGCCCCTGTGCATGTTGGACATCTTTGTGCTGATTGCCTCTGTGCCAGTGGTTG CTGTGGGAAACCAAGGCAATGTTCTGGCCACCTCCCTGCGAAGCCTGCGCTTCCTGCAGATCCTGCGCAT GCTGCGGATGGACCGGAGAGGTGGCACCTGGAAGCTTCTGGGCTCAGCCATCTGTGCCCACAGCAAAGAA CTCATCACGGCCTGGTACATCGGTTTCCTGACACTCATCCTTTCTTCATTTCTTGTCTACCTGGTTGAGA AAGACGTCCCAGAGGTGGATGCACAAGGAGAGGAGATGAAAGAGGAGTTTGAGACCTATGCAGATGCCCT GTGGTGGGGCCTGATCACACTGGCCACCATTGGCTATGGAGACAAGACACCCAAAACGTGGGAAGGCCGT CTGATTGCCGCCACCTTTTCCTTAATTGGCGTCTCCTTTTTTGCCCTTCCAGCGGGCATCCTGGGGTCCG GGCTGGCCCTCAAGGTGCAGGAGCAACACCGTCAGAAGCACTTTGAGAAAAGGAGGAAGCCAGCTGCTGA GCTCATTCAGGCTGCCTGGAGGTATTATGCTACCAACCCCAACAGGATTGACCTGGTGGCGACATGGAGA TTTTATGAATCAGTCGTCTCTTTTCCTTTCTTCAGGAAAGAACAGCTGGAGGCAGCATCCAGCCAAAAGC TGGGTCTCTTGGATCGGGTTCGCCTTTCTAATCCTCGTGGTAGCAATACTAAAGGAAAGCTATTTACCCC TCTGAATGTAGATGCCATAGAAGAAAGTCCTTCTAAAGAACCAAAGCCTGTTGGCTTAAACAATAAAGAG CGTTTCCGCACGGCCTTCCGCATGAAAGCCTACGCTTTCTGGCAGAGTTCTGAAGATGCCGGGACAGGTG ACCCCATGGCGGAAGACAGGGGCTATGGGAATGACTTCCCCATCGAAGACATGATCCCCACCCTGAAGGC CGCCATCCGAGCCGTCAGAATTCTACAATTCCGTCTCTATAAAAAAAAATTCAAGGAGACTTTGAGGCCT TACGATGTGAAGGATGTGATTGAGCAGTATTCTGCCGGGCATCTCGACATGCTTTCCAGGATAAAGTACC TTCAGACGAGAATAGATATGATTTTCACCCCTGGACCTCCCTCCACGCCAAAACACAAGAAGTCTCAGAA AGGGTCAGCATTCACCTTCCCATCCCAGCAATCTCCCAGGAATGAACCATATGTAGCCAGACCATCCACA TCAGAAATCGAAGACCAAAGCATGATGGGGAAGTTTGTAAAAGTTGAAAGACAGGTTCAGGACATGGGGA AGAAGCTGGACTTCCTCGTGGATATGCACATGCAACACATGGAACGGTTGCAGGTGCAGGTCACGGAGTA TTACCCAACCAAGGGCACCTCCTCGCCAGCTGAAGCAGAGAAGAAGGAGGACAACAGGTATTCCGATTTG AAAACCATCATCTGCAACTATTCTGAGACAGGCCCCCCGGAACCACCCTACAGCTTCCACCAGGTGACCA TTGACAAAGTCAGCCCCTATGGGTTTTTTGCACATGACCCTGTGAACCTGCCCCGAGGGGGACCCAGTTC TGGAAAGGTTCAGGCAACTCCTCCTTCCTCAGCAACAACGTATGTGGAGAGGCCCACGGTCCTGCCTATC TTGACTCTTCTCGACTCCCGAGTGAGCTGCCACTCCCAGGCTGACCTGCAGGGCCCCTACTCGGACCGAA TCTCCCCCCGGCAGAGACGTAGCATCACGCGAGACAGTGACACACCTCTGTCCCTGATGTCGGTCAACCA CGAGGAGCTGGAGAGGTCTCCAAGTGGCTTCAGCATCTCCCAGGACAGAGATGATTATGTGTTCGGCCCC AATGGGGGGTCGAGCTGGATGAGGGAGAAGCGGTACCTCGCCGAGGGTGAGACGGACACAGACACGGACC CCTTCACGCCCAGCGGCTCCATGCCTCTGTCGTCCACAGGGGATGGGATTTCTGATTCAGTATGGACCCC TTCCAATAAGCCCATT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC234832 representing NM_001204824
Red=Cloning site Green=Tags(s) MKPAEHATMFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGR LKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE LITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGR LIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR FYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKE RFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPST SEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDL KTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPI LTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGP NGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001204824 |
ORF Size | 2256 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001204824.1, NP_001191753.1 |
RefSeq Size | 10717 |
RefSeq ORF | 2259 |
Locus ID | 3786 |
Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
MW | 85.3 kDa |
Gene Summary | This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC331612 | KCNQ3 (untagged) - Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 2 |
USD 760.00 |
|
RG234832 | KCNQ3 (GFP-tagged) - Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 2 |
USD 670.00 |
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