KCNQ3 (NM_001204824) Human Untagged Clone

CAT#: SC331612

KCNQ3 (untagged) - Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNQ3
• Synonyms: BFNC2; EBN2; KV7.3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001204824, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCCTGCAGAACACGCCACGATGTTCCTGATTGTCCTGGGGTGCTTGATTCTGGCTGTCCTGACCA
  CATTCAAGGAGTATGAGACTGTCTCGGGAGACTGGCTTCTGTTACTGGAGACATTTGCTATTTTCATCTT
  TGGAGCCGAGTTTGCTTTGAGGATCTGGGCTGCTGGATGTTGCTGCCGATACAAAGGCTGGCGGGGCCGA
  CTGAAGTTTGCCAGGAAGCCCCTGTGCATGTTGGACATCTTTGTGCTGATTGCCTCTGTGCCAGTGGTTG
  CTGTGGGAAACCAAGGCAATGTTCTGGCCACCTCCCTGCGAAGCCTGCGCTTCCTGCAGATCCTGCGCAT
  GCTGCGGATGGACCGGAGAGGTGGCACCTGGAAGCTTCTGGGCTCAGCCATCTGTGCCCACAGCAAAGAA
  CTCATCACGGCCTGGTACATCGGTTTCCTGACACTCATCCTTTCTTCATTTCTTGTCTACCTGGTTGAGA
  AAGACGTCCCAGAGGTGGATGCACAAGGAGAGGAGATGAAAGAGGAGTTTGAGACCTATGCAGATGCCCT
  GTGGTGGGGCCTGATCACACTGGCCACCATTGGCTATGGAGACAAGACACCCAAAACGTGGGAAGGCCGT
  CTGATTGCCGCCACCTTTTCCTTAATTGGCGTCTCCTTTTTTGCCCTTCCAGCGGGCATCCTGGGGTCCG
  GGCTGGCCCTCAAGGTGCAGGAGCAACACCGTCAGAAGCACTTTGAGAAAAGGAGGAAGCCAGCTGCTGA
  GCTCATTCAGGCTGCCTGGAGGTATTATGCTACCAACCCCAACAGGATTGACCTGGTGGCGACATGGAGA
  TTTTATGAATCAGTCGTCTCTTTTCCTTTCTTCAGGAAAGAACAGCTGGAGGCAGCATCCAGCCAAAAGC
  TGGGTCTCTTGGATCGGGTTCGCCTTTCTAATCCTCGTGGTAGCAATACTAAAGGAAAGCTATTTACCCC
  TCTGAATGTAGATGCCATAGAAGAAAGTCCTTCTAAAGAACCAAAGCCTGTTGGCTTAAACAATAAAGAG
  CGTTTCCGCACGGCCTTCCGCATGAAAGCCTACGCTTTCTGGCAGAGTTCTGAAGATGCCGGGACAGGTG
  ACCCCATGGCGGAAGACAGGGGCTATGGGAATGACTTCCCCATCGAAGACATGATCCCCACCCTGAAGGC
  CGCCATCCGAGCCGTCAGAATTCTACAATTCCGTCTCTATAAAAAAAAATTCAAGGAGACTTTGAGGCCT
  TACGATGTGAAGGATGTGATTGAGCAGTATTCTGCCGGGCATCTCGACATGCTTTCCAGGATAAAGTACC
  TTCAGACGAGAATAGATATGATTTTCACCCCTGGACCTCCCTCCACGCCAAAACACAAGAAGTCTCAGAA
  AGGGTCAGCATTCACCTTCCCATCCCAGCAATCTCCCAGGAATGAACCATATGTAGCCAGACCATCCACA
  TCAGAAATCGAAGACCAAAGCATGATGGGGAAGTTTGTAAAAGTTGAAAGACAGGTTCAGGACATGGGGA
  AGAAGCTGGACTTCCTCGTGGATATGCACATGCAACACATGGAACGGTTGCAGGTGCAGGTCACGGAGTA
  TTACCCAACCAAGGGCACCTCCTCGCCAGCTGAAGCAGAGAAGAAGGAGGACAACAGGTATTCCGATTTG
  AAAACCATCATCTGCAACTATTCTGAGACAGGCCCCCCGGAACCACCCTACAGCTTCCACCAGGTGACCA
  TTGACAAAGTCAGCCCCTATGGGTTTTTTGCACATGACCCTGTGAACCTGCCCCGAGGGGGACCCAGTTC
  TGGAAAGGTTCAGGCAACTCCTCCTTCCTCAGCAACAACGTATGTGGAGAGGCCCACGGTCCTGCCTATC
  TTGACTCTTCTCGACTCCCGAGTGAGCTGCCACTCCCAGGCTGACCTGCAGGGCCCCTACTCGGACCGAA
  TCTCCCCCCGGCAGAGACGTAGCATCACGCGAGACAGTGACACACCTCTGTCCCTGATGTCGGTCAACCA
  CGAGGAGCTGGAGAGGTCTCCAAGTGGCTTCAGCATCTCCCAGGACAGAGATGATTATGTGTTCGGCCCC
  AATGGGGGGTCGAGCTGGATGAGGGAGAAGCGGTACCTCGCCGAGGGTGAGACGGACACAGACACGGACC
  CCTTCACGCCCAGCGGCTCCATGCCTCTGTCGTCCACAGGGGATGGGATTTCTGATTCAGTATGGACCCC
  TTCCAATAAGCCCATTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001204824
• ORF Size: 2259 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001204824.1, NP_001191753.1
• RefSeq Size: 10717
• RefSeq ORF: 2259
• Locus ID: 3786
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
  Transcript Variant: This variant (2) contains an alternate 5' terminal exon and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.