PXK (NM_001289100) Human Tagged ORF Clone

CAT#: RC238489

PXK (myc-DDK-tagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 6

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC238489 representing NM_001289100
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCCA
  TCGAGGCGAGCCAGAGCCTGCAGTCCCACACGATTGCAGGCCTAAGTCTACCTCTTCCTCCCAAAAAATT
  GATTGGTAACATGGATCGTGAATTCATAGCTGAAAGGCAGAAAGGTCTTCAGAACTATCTCAACGTGATC
  ACAACAAATCATATCTTGTCTAATTGTGAGCTGGTTAAGAAGTTTTTAGATCCAAACAACTATTCCGCAA
  ACTATACTGAGATTGCCTTGCAACAGGTTTCCATGTTCTTCCGATCAGAACCAAAGTGGGAGGTGGTGGA
  ACCTTTGAAAGACATAGGTTGGAGAATAAGGAAGAAATATTTCTTGATGAAGATTAAAAATCAGCCAAAG
  GAACGGCTAGTGTTAAGCTGGGCTGACCTTGGCCCAGACAAGTATTTGTCAGATAAAGATTTTCAGTGTC
  TAATCAAACTTCTGCCTTCTTGTTTGCACCCTTACATCTATCGGGTTACCTTTGCCACAGCTAATGAATC
  CTCAGCGTTGCTAATTAGGATGTTTAACGAAAAGGGAACATTGAAGGATCTGATCTACAAGGCAAAACCA
  AAAGACCCATTTCTAAAGAAGTACTGCAACCCTAAGAAGATTCAGGGCCTGGAACTCCAGCAAATAAAAA
  CATATGGACGGCAAATATTAGAGGTACTGAAGTTTCTTCATGACAAGGGATTCCCTTATGGGCATCTTCA
  CGCCTCCAATGTGATGCTCGATGGGGACACTTGCCGGCTGCTGGACCTTGAGAATTCCTTATTGGGCCTG
  CCTTCCTTCTACCGATCTTATTTTTCACAATTCAGGAAAATCAATACATTGGAAAGTGTGGATGTCCACT
  GCTTTGGCCACTTACTGTATGAAATGACTTATGGACGACCGCCAGACTCGGTGCCTGTGGACTCCTTCCC
  TCCTGCCCCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAAGCCTGTAAAAATGGC
  ATGCCTACCATCTCCCGGCTCTTACAGATGCCATTATTCAGCGATGTTTTACTAACCACTTCTGAAAAAC
  CACAGTTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGAATTGCCAAAGAATGTATAGAGAAGAGACT
  AATTGAGGAACAGAAACAGATTCACCAGCATCGAAGACTGACAAGAGCTCAGTCCCACCATGGATCTGAG
  GAGGAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTCAAAACGATCTGCTCTTGAAAATAGTGAAG
  AGCATTCAGCGAAGTACAGCAACTCCAATAATTCAGCAGGATCTGGGGCCAGCTCACCTCTCACGTCCCC
  GTCATCGCCAACTCCACCCTCTACATCAGTAGAGCATGCACCATTT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC238489 representing NM_001289100
  Red=Cloning site Green=Tags(s)
  
  MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVI
  TTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPK
  ERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAKP
  KDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGL
  PSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCEACKNG
  MPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSE
  EERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSVEHAPF
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289100
• ORF Size: 1446 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001289100.1, NP_001276029.1
• RefSeq Size: 2954
• RefSeq ORF: 1449
• Locus ID: 54899
• Protein Families: Druggable Genome, Protein Kinase
• MW: 55.2 kDa
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]