PXK (NM_001289100) Human Untagged Clone

CAT#: SC336383

PXK (untagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001289100, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCCA
  TCGAGGCGAGCCAGAGCCTGCAGTCCCACACGATTGCAGGCCTAAGTCTACCTCTTCCTCCCAAAAAATT
  GATTGGTAACATGGATCGTGAATTCATAGCTGAAAGGCAGAAAGGTCTTCAGAACTATCTCAACGTGATC
  ACAACAAATCATATCTTGTCTAATTGTGAGCTGGTTAAGAAGTTTTTAGATCCAAACAACTATTCCGCAA
  ACTATACTGAGATTGCCTTGCAACAGGTTTCCATGTTCTTCCGATCAGAACCAAAGTGGGAGGTGGTGGA
  ACCTTTGAAAGACATAGGTTGGAGAATAAGGAAGAAATATTTCTTGATGAAGATTAAAAATCAGCCAAAG
  GAACGGCTAGTGTTAAGCTGGGCTGACCTTGGCCCAGACAAGTATTTGTCAGATAAAGATTTTCAGTGTC
  TAATCAAACTTCTGCCTTCTTGTTTGCACCCTTACATCTATCGGGTTACCTTTGCCACAGCTAATGAATC
  CTCAGCGTTGCTAATTAGGATGTTTAACGAAAAGGGAACATTGAAGGATCTGATCTACAAGGCAAAACCA
  AAAGACCCATTTCTAAAGAAGTACTGCAACCCTAAGAAGATTCAGGGCCTGGAACTCCAGCAAATAAAAA
  CATATGGACGGCAAATATTAGAGGTACTGAAGTTTCTTCATGACAAGGGATTCCCTTATGGGCATCTTCA
  CGCCTCCAATGTGATGCTCGATGGGGACACTTGCCGGCTGCTGGACCTTGAGAATTCCTTATTGGGCCTG
  CCTTCCTTCTACCGATCTTATTTTTCACAATTCAGGAAAATCAATACATTGGAAAGTGTGGATGTCCACT
  GCTTTGGCCACTTACTGTATGAAATGACTTATGGACGACCGCCAGACTCGGTGCCTGTGGACTCCTTCCC
  TCCTGCCCCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAAGCCTGTAAAAATGGC
  ATGCCTACCATCTCCCGGCTCTTACAGATGCCATTATTCAGCGATGTTTTACTAACCACTTCTGAAAAAC
  CACAGTTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGAATTGCCAAAGAATGTATAGAGAAGAGACT
  AATTGAGGAACAGAAACAGATTCACCAGCATCGAAGACTGACAAGAGCTCAGTCCCACCATGGATCTGAG
  GAGGAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTCAAAACGATCTGCTCTTGAAAATAGTGAAG
  AGCATTCAGCGAAGTACAGCAACTCCAATAATTCAGCAGGATCTGGGGCCAGCTCACCTCTCACGTCCCC
  GTCATCGCCAACTCCACCCTCTACATCAGTAGAGCATGCACCATTTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289100
• ORF Size: 1449 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001289100.1, NP_001276029.1
• RefSeq Size: 2954
• RefSeq ORF: 1449
• Locus ID: 54899
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (6) lacks two consecutive, alternate, in-frame exons in the 5' coding region and contains an alternate exon in the 3' region, resulting in an early stop codon, compared to variant 1. It encodes isoform f (also known as isoform 6), which is shorter and has a distinct C-terminus, compared to isoform a. Variants 6 and 10 both encode the same isoform (f).