KDM5C (NM_001282622) Human Tagged ORF Clone

CAT#: RC240178L4

Lenti-ORF clone of KDM5C (mGFP-tagged)-Human lysine (K)-specific demethylase 5C (KDM5C), transcript variant 3

Specifications

Product Data

• Tag: mGFP
• Symbol: KDM5C
• Synonyms: DXS1272E; JARID1C; MRX13; MRXJ; MRXSCJ; MRXSJ; SMCX; XE169
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC240178).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001282622
• ORF Size: 4677 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001282622.2, NP_001269551.1
• RefSeq Size: 6644
• RefSeq ORF: 4680
• Locus ID: 8242
• Protein Families: Druggable Genome, Transcription Factors
• MW: 175.6 kDa
• Gene Summary: This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]