KCNK6 (NM_004823) Human Tagged ORF Clone

CAT#: RG202421

KCNK6 (GFP-tagged) - Human potassium channel, subfamily K, member 6 (KCNK6)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: KCNK6
• Synonyms: K2p6.1; KCNK8; TOSS; TWIK-2; TWIK2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG202421 representing NM_004823
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGGAGGGGCGCGCTTCTGGCGGGCGCCTTGGCCGCGTACGCCGCGTACCTGGTGCTGGGCGCGCTGT
  TGGTGGCGCGGCTGGAGGGGCCGCACGAAGCCAGGCTCCGAGCCGAGCTGGAGACGCTGCGGGCGCAGCT
  GCTTCAGCGCAGCCCGTGTGTGGCTGCCCCCGCCCTGGACGCCTTCGTGGAGCGAGTGCTGGCGGCCGGA
  CGGCTGGGGCGGGTCGTGCTTGCTAACGCTTCGGGGTCCGCCAACGCCTCGGACCCCGCCTGGGACTTCG
  CCTCTGCTCTCTTCTTCGCCAGCACGCTGATCACCACCGTGGGCTATGGGTACACAACGCCACTGACTGA
  TGCGGGCAAGGCCTTCTCCATCGCCTTTGCGCTCCTGGGCGTGCCGACCACCATGCTGCTGCTGACCGCC
  TCAGCCCAGCGCCTGTCACTGCTGCTGACTCACGTGCCCCTGTCTTGGCTGAGCATGCGTTGGGGCTGGG
  ACCCCCGGCGGGCGGCCTGCTGGCACTTGGTGGCCCTGTTGGGGGTCGTAGTGACCGTCTGCTTTCTGGT
  GCCGGCTGTGATCTTTGCCCACCTCGAGGAGGCCTGGAGCTTCTTGGATGCCTTCTACTTCTGCTTTATC
  TCTCTGTCCACCATCGGCCTGGGCGACTACGTGCCCGGGGAGGCCCCTGGCCAGCCCTACCGGGCCCTCT
  ACAAGGTGCTGGTCACAGTCTACCTCTTCCTGGGCCTGGTGGCCATGGTGCTGGTGCTGCAGACCTTCCG
  CCACGTGTCCGACCTCCACGGCCTCACGGAGCTCATCCTGCTGCCCCCTCCGTGCCCTGCCAGTTTCAAT
  GCGGATGAGGACGATCGGGTGGACATCCTGGGCCCCCAGCCGGAGTCGCACCAGCAACTCTCTGCCAGCT
  CCCACACCGACTACGCTTCCATCCCCAGG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG202421 representing NM_004823
  Red=Cloning site Green=Tags(s)
  
  MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAG
  RLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTA
  SAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFI
  SLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFN
  ADEDDRVDILGPQPESHQQLSASSHTDYASIPR
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_004823
• ORF Size: 939 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004823.1, NP_004814.1
• RefSeq Size: 2671
• RefSeq ORF: 942
• Locus ID: 9424
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008]