UPP2 (NM_173355) Human Tagged ORF Clone

CAT#: RG207260

UPP2 (GFP-tagged) - Human uridine phosphorylase 2 (UPP2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: UPP2
• Synonyms: UDRPASE2; UP2; UPASE2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG207260 representing NM_173355
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTTCAGTTATACCTGCCTCCAATAGGTCCATGAGATCTGACAGGAATACATATGTTGGAAAAAGGT
  TTGTTCACGTTAAAAATCCTTACTTGGATTTGATGGATGAAGACATTCTCTATCACTTGGATTTGGGAAC
  AAAAACACACAACCTACCAGCAATGTTTGGAGATGTAAAGTTTGTCTGTGTCGGTGGGAGCCCCAACAGA
  ATGAAAGCATTTGCACTGTTTATGCACAAGGAGCTCGGGTTTGAGGAAGCTGAAGAAGACATAAAAGACA
  TCTGTGCTGGGACAGACAGATACTGTATGTACAAAACCGGGCCTGTGCTCGCCATCAGTCACGGCATGGG
  CATCCCCTCCATTTCTATTATGCTTCATGAACTCATCAAATTACTCCACCATGCACGGTGCTGCGATGTC
  ACCATTATTAGAATCGGTACATCAGGGGGAATAGGGATTGCACCAGGGACTGTTGTAATAACGGATATAG
  CTGTAGACTCCTTCTTTAAGCCCCGGTTTGAACAGGTCATTTTGGACAACATTGTCACCCGAAGTACTGA
  ACTGGACAAAGAACTGTCTGAAGAACTGTTCAACTGTAGCAAAGAAATCCCCAACTTCCCAACCCTCGTT
  GGACATACAATGTGTACCTATGATTTTTATGAAGGCCAAGGCCGACTAGATGGAGCACTGTGCTCCTTTT
  CCAGAGAAAAAAAGTTAGACTACTTGAAGAGAGCATTTAAAGCTGGTGTCAGGAATATTGAAATGGAATC
  TACAGTGTTTGCAGCTATGTGTGGACTCTGTGGTCTAAAAGCTGCTGTGGTCTGTGTGACACTTCTCGAC
  AGACTCGACTGTGATCAGATCAACTTGCCTCATGATGTCCTGGTGGAGTACCAGCAACGGCCTCAGCTCC
  TAATCTCCAACTTCATCAGACGGCGGCTTGGACTTTGTGAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG207260 representing NM_173355
  Red=Cloning site Green=Tags(s)
  
  MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNR
  MKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDV
  TIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPNFPTLV
  GHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLD
  RLDCDQINLPHDVLVEYQQRPQLLISNFIRRRLGLCD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_173355
• ORF Size: 951 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_173355.2, NP_775491.1
• RefSeq Size: 2236
• RefSeq ORF: 954
• Locus ID: 151531
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
• Gene Summary: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. [UniProtKB/Swiss-Prot Function]