PREB (NM_013388) Human Tagged ORF Clone

CAT#: RG208351

PREB (GFP-tagged) - Human prolactin regulatory element binding (PREB)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PREB
• Synonyms: SEC12
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG208351 representing NM_013388
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCCGGCGCCGGGCGCCAGAGCTGTACCGGGCTCCGTTCCCGTTGTACGCGCTTCAGGTCGACCCCA
  GCACTGGGCTGCTCATCGCTGCGGGCGGAGGAGGCGCCGCCAAGACAGGCATAAAGAATGGCGTGCACTT
  TCTGCAGCTAGAGCTGATTAATGGGCGCTTGAGTGCCTCCTTGCTGCACTCCCATGACACAGAGACACGG
  GCCACCATGAACTTGGCACTGGCTGGTGACATCCTTGCTGCAGGGCAGGATGCCCACTGTCAGCTCCTGC
  GCTTCCAGGCACATCAACAGCAGGGCAACAAGGCAGAGAAGGCCGGTTCCAAGGAGCAGGGGCCTCGACA
  AAGGAAGGGAGCAGCCCCAGCAGAGAAGAAATGTGGAGCGGAAACCCAGCACGAGGGGCTAGAACTCAGG
  GTAGAGAATTTGCAGGCGGTGCAGACAGACTTTAGCTCCGATCCACTGCAGAAAGTTGTGTGCTTCAACC
  ACGATAATACCCTGCTTGCCACTGGAGGAACAGATGGCTACGTCCGTGTCTGGAAGGTGCCCAGCCTGGA
  GAAGGTTCTGGAGTTCAAAGCCCACGAAGGGGAGATTGAAGACCTGGCTTTAGGGCCTGATGGCAAGTTG
  GTAACCGTGGGCCGGGACCTTAAGGCCTCTGTGTGGCAGAAGGATCAGCTGGTGACACAGCTGCACTGGC
  AAGAAAATGGACCCACCTTTTCCAGCACACCTTACCGCTACCAGGCCTGCAGGTTTGGGCAGGTTCCAGA
  CCAGCCTGCTGGCCTGCGACTCTTCACAGTGCAAATTCCCCACAAGCGCCTGCGCCAGCCCCCTCCCTGC
  TACCTCACAGCCTGGGATGGCTCCAACTTCTTGCCCCTTCGGACCAAGTCCTGTGGCCATGAAGTCGTCT
  CCTGCCTCGATGTCAGTGAATCCGGCACCTTCCTAGGCCTGGGCACAGTCACTGGCTCTGTTGCCATCTA
  CATAGCTTTCTCTCTCCAGTGCCTCTACTACGTGAGGGAGGCCCATGGCATTGTGGTGACGGATGTGGCC
  TTTCTACCTGAGAAGGGTCGTGGTCCAGAGCTCCTTGGGTCCCATGAAACTGCCCTGTTCTCTGTGGCTG
  TGGACAGTCGTTGCCAGCTGCATCTGTTGCCCTCACGGCGGAGTGTTCCTGTGTGGCTCCTGCTCCTGCT
  GTGTGTCGGGCTTATTATTGTGACCATCCTGCTGCTCCAGAGTGCCTTTCCAGGTTTCCTT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG208351 representing NM_013388
  Red=Cloning site Green=Tags(s)
  
  MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSASLLHSHDTETR
  ATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELR
  VENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL
  VTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC
  YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVA
  FLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013388
• ORF Size: 1251 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013388.4, NP_037520.1
• RefSeq Size: 2211
• RefSeq ORF: 1254
• Locus ID: 10113
• Domains: WD40
• Protein Families: Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]