TACI (TNFRSF13B) (NM_012452) Human Tagged ORF Clone

CAT#: RG211856

TNFRSF13B (GFP-tagged) - Human tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: TNFRSF13B
• Synonyms: CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG211856 representing NM_012452
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTGGCCTGGGCCGGAGCAGGCGAGGTGGCCGGAGCCGTGTGGACCAGGAGGAGCGCTTTCCACAGG
  GCCTGTGGACGGGGGTGGCTATGAGATCCTGCCCCGAAGAGCAGTACTGGGATCCTCTGCTGGGTACCTG
  CATGTCCTGCAAAACCATTTGCAACCATCAGAGCCAGCGCACCTGTGCAGCCTTCTGCAGGTCACTCAGC
  TGCCGCAAGGAGCAAGGCAAGTTCTATGACCATCTCCTGAGGGACTGCATCAGCTGTGCCTCCATCTGTG
  GACAGCACCCTAAGCAATGTGCATACTTCTGTGAGAACAAGCTCAGGAGCCCAGTGAACCTTCCACCAGA
  GCTCAGGAGACAGCGGAGTGGAGAAGTTGAAAACAATTCAGACAACTCGGGAAGGTACCAAGGATTGGAG
  CACAGAGGCTCAGAAGCAAGTCCAGCTCTCCCGGGGCTGAAGCTGAGTGCAGATCAGGTGGCCCTGGTCT
  ACAGCACGCTGGGGCTCTGCCTGTGTGCCGTCCTCTGCTGCTTCCTGGTGGCGGTGGCCTGCTTCCTCAA
  GAAGAGGGGGGATCCCTGCTCCTGCCAGCCCCGCTCAAGGCCCCGTCAAAGTCCGGCCAAGTCTTCCCAG
  GATCACGCGATGGAAGCCGGCAGCCCTGTGAGCACATCCCCCGAGCCAGTGGAGACCTGCAGCTTCTGCT
  TCCCTGAGTGCAGGGCGCCCACGCAGGAGAGCGCAGTCACGCCTGGGACCCCCGACCCCACTTGTGCTGG
  AAGGTGGGGGTGCCACACCAGGACCACAGTCCTGCAGCCTTGCCCACACATCCCAGACAGTGGCCTTGGC
  ATTGTGTGTGTGCCTGCCCAGGAGGGGGGCCCAGGTGCA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG211856 representing NM_012452
  Red=Cloning site Green=Tags(s)
  
  MSGLGRSRRGGRSRVDQEERFPQGLWTGVAMRSCPEEQYWDPLLGTCMSCKTICNHQSQRTCAAFCRSLS
  CRKEQGKFYDHLLRDCISCASICGQHPKQCAYFCENKLRSPVNLPPELRRQRSGEVENNSDNSGRYQGLE
  HRGSEASPALPGLKLSADQVALVYSTLGLCLCAVLCCFLVAVACFLKKRGDPCSCQPRSRPRQSPAKSSQ
  DHAMEAGSPVSTSPEPVETCSFCFPECRAPTQESAVTPGTPDPTCAGRWGCHTRTTVLQPCPHIPDSGLG
  IVCVPAQEGGPGA
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_012452
• ORF Size: 879 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_012452.2, NP_036584.1
• RefSeq Size: 1377
• RefSeq ORF: 882
• Locus ID: 23495
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Primary immunodeficiency
• Gene Summary: The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]