NPAS3 (NM_173159) Human Tagged ORF Clone

CAT#: RG217769

NPAS3 (GFP-tagged) - Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: NPAS3
• Synonyms: bHLHe12; MOP6; PASD6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG217769 representing NM_173159
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCCCACCAAGCCCAGCTTTCAGCAGGATCCTTCCAGGCGAGAACGTTTACAAGCATTGAGAAAGG
  AGAAATCCCGAGATGCTGCTCGCTCCCGCCGGGGAAAAGAAAACTTTGAGTTCTATGAATTGGCCAAGTT
  GTTGCCTCTTCCTGCAGCCATTACCAGCCAGCTCGACAAGGCATCCATCATTCGACTTACAATTAGCTAT
  CTGAAAATGAGGGACTTTGCTAACCAGGGGGACCCTCCGTGGAACTTGCGAATGGAAGGCCCTCCACCTA
  ACACATCAGTAAAAGGGATACAAATGTGGAAATCTGAACTCTGCATGAGAAAGACACCATGTGAAGGTGC
  ACAGCGAAGGAGAAGCCCCAGTGCACTAGCCATTGAAGTATTTGAAGCACATTTGGGAAGCCACATTTTG
  CAGTCCCTGGATGGCTTTGTATTTGCACTAAATCAGGAAGGAAAATTTTTGTACATTTCCGAAACAGTCT
  CCATCTACCTAGGCCTCTCACAAGTGGAGCTGACAGGCAGCAGTGTCTTTGACTATGTCCACCCCGGAGA
  TCACGTGGAGATGGCTGAGCAGCTGGGCATGAAGCTCCCCCCTGGGCGGGGTCTCCTGTCACAGGGCACT
  GCTGAGGACGGAGCCAGCTCAGCATCTTCCTCCTCTCAGTCGGAGACCCCCGAGCCAGTGGAGTCAACCA
  GCCCCAGTCTGCTAACCACTGACAACACTCTTGAGCGTTCCTTTTTCATCCGAATGAAATCTACTCTGAC
  CAAACGCGGTGTGCACATCAAATCATCAGGATATAAGGTGATTCACATAACAGGCCGGCTACGCCTGAGA
  GTGTCGCTGTCCCACGGGAGGACCGTCCCCAGCCAAATCATGGGTCTCGTGGTTGTTGCGCATGCCTTGC
  CTCCCCCTACGATCAATGAAGTCAGAATTGACTGCCATATGTTCGTCACTCGAGTAAATATGGACCTCAA
  TATCATTTACTGTGAAAATAGGATTAGTGATTATATGGATCTGACCCCTGTAGATATCGTAGGGAAGAGA
  TGCTACCACTTCATCCATGCTGAAGACGTGGAGGGCATCAGGCACAGTCACTTGGACTTGCTGAATAAGG
  GTCAGTGTGTGACAAAGTACTATCGCTGGATGCAGAAGAACGGAGGATATATTTGGATACAGTCCAGTGC
  CACCATAGCTATTAATGCCAAGAATGCAAATGAAAAGAATATCATCTGGGTGAATTACCTTCTTAGCAAT
  CCTGAGTACAAGGACACACCCATGGACATCGCACAGCTCCCCCATCTGCCGGAGAAAACTTCCGAATCCT
  CGGAGACATCCGACTCTGAGTCAGACTCTAAAGACACCTCAGAGGACAACGAGAACTCCAAGTCCGACGA
  GAAGGGGAACCAGTCCGAGAACAGCGAAGACCCGGAGCCCGACCGGAAGAAGTCGGGCAACGCGTGTGAC
  AACGACATGAACTGCAACGACGACGGCCACAGCTCCAGTAACCCGGACAGCCGCGACAGCGACGACAGCT
  TCGAGCACTCGGACTTTGAGAACCCCAAGGCGGGCGAGGACGGCTTCGGTGCTCTGGGCGCGATGCAGAT
  CAAGGTGGAGCGCTACGTGGAGAGCGAGTCGGACCTGCGGCTGCAGAACTGCGAGTCACTCACGTCCGAC
  AGCGCCAAGGACTCGGACAGCGCAGGCGAGGCGGGCGCGCAGGCCTCCAGCAAGCACCAGAAGCGCAAGA
  AAAGGCGGAAACGGCAAAAGGGCGGCAGCGCCAGCCGCCGGCGCCTGTCCAGCGCGTCGAGCCCAGGCGG
  CCTGGACGCGGGCCTGGTGGAGCCCCCGCGGCTGCTGTCCTCCCCCAACAGTGCCTCGGTGCTCAAGATC
  AAGACGGAGATCTCAGAACCCATCAATTTCGACAATGACAGCAGCATCTGGAACTACCCGCCCAACCGGG
  AGATCTCCAGGAACGAGTCCCCCTACAGCATGACCAAGCCCCCCAGCTCTGAGCACTTCCCGTCCCCGCA
  GGGCGGCGGCGGTGGGGGTGGCGGTGGCGGGGGGCTGCACGTGGCCATTCCCGACTCGGTCCTCACCCCG
  CCCGGCGCCGACGGCGCGGCCGCCCGCAAGACTCAGTTCGGCGCCTCGGCCACCGCGGCCCTGGCCCCCG
  TCGCCTCCGACCCGCTGTCACCCCCGCTCTCGGCGTCCCCGCGGGACAAGCACCCCGGGAACGGCGGCGG
  GGGCGGGGGCGGGGGCGGCGGCGCGGGGGGCGGCGGCCCCAGCGCGTCCAACTCCTTGCTGTACACTGGG
  GACCTGGAGGCGCTGCAGAGGTTGCAGGCGGGCAACGTCGTGCTCCCGCTGGTGCACAGGGTGACCGGGA
  CCCTGGCCGCCACCAGCACGGCCGCGCAGAGGGTCTACACCACGGGCACCATCCGCTACGCGCCCGCCGA
  GGTGACCCTGGCCATGCAGAGCAACCTGCTGCCCAACGCGCACGCTGTTAACTTCGTGGACGTTAACAGC
  CCCGGCTTTGGCCTCGACCCCAAGACGCCCATGGAGATGCTCTACCACCACGTGCACCGGCTCAACATGT
  CAGGACCGTTCGGCGGCGCAGTGAGCGCAGCTAGCCTGACGCAGATGCCCGCCGGCAACGTGTTCACCAC
  GGCCGAGGGACTCTTCTCCACGCTGCCCTTCCCCGTCTACAGCAACGGCATCCACGCGGCACAGACTCTG
  GAGCGCAAGGAGGAC
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG217769 representing NM_173159
  Red=Cloning site Green=Tags(s)
  
  MAPTKPSFQQDPSRRERLQALRKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISY
  LKMRDFANQGDPPWNLRMEGPPPNTSVKGIQMWKSELCMRKTPCEGAQRRRSPSALAIEVFEAHLGSHIL
  QSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRGLLSQGT
  AEDGASSASSSSQSETPEPVESTSPSLLTTDNTLERSFFIRMKSTLTKRGVHIKSSGYKVIHITGRLRLR
  VSLSHGRTVPSQIMGLVVVAHALPPPTINEVRIDCHMFVTRVNMDLNIIYCENRISDYMDLTPVDIVGKR
  CYHFIHAEDVEGIRHSHLDLLNKGQCVTKYYRWMQKNGGYIWIQSSATIAINAKNANEKNIIWVNYLLSN
  PEYKDTPMDIAQLPHLPEKTSESSETSDSESDSKDTSEDNENSKSDEKGNQSENSEDPEPDRKKSGNACD
  NDMNCNDDGHSSSNPDSRDSDDSFEHSDFENPKAGEDGFGALGAMQIKVERYVESESDLRLQNCESLTSD
  SAKDSDSAGEAGAQASSKHQKRKKRRKRQKGGSASRRRLSSASSPGGLDAGLVEPPRLLSSPNSASVLKI
  KTEISEPINFDNDSSIWNYPPNREISRNESPYSMTKPPSSEHFPSPQGGGGGGGGGGGLHVAIPDSVLTP
  PGADGAAARKTQFGASATAALAPVASDPLSPPLSASPRDKHPGNGGGGGGGGGGAGGGGPSASNSLLYTG
  DLEALQRLQAGNVVLPLVHRVTGTLAATSTAAQRVYTTGTIRYAPAEVTLAMQSNLLPNAHAVNFVDVNS
  PGFGLDPKTPMEMLYHHVHRLNMSGPFGGAVSAASLTQMPAGNVFTTAEGLFSTLPFPVYSNGIHAAQTL
  ERKED
  
  SGPTRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_173159
• ORF Size: 2760 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_173159.1, NP_775182.1
• RefSeq Size: 5900
• RefSeq ORF: 2763
• Locus ID: 64067
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]