NPAS3 (NM_173159) Human Untagged Clone

CAT#: SC306790

NPAS3 (untagged)-Human neuronal PAS domain protein 3 (NPAS3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NPAS3
• Synonyms: bHLHe12; MOP6; PASD6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_173159 edited
  ATGGCGCCCACCAAGCCCAGCTTTCAGCAGGATCCTTCCAGGCGAGAACGTTTACAAGCA
  TTGAGAAAGGAGAAATCCCGAGATGCTGCTCGCTCCCGCCGGGGAAAAGAAAACTTTGAG
  TTCTATGAATTGGCCAAGTTGTTGCCTCTTCCTGCAGCCATTACCAGCCAGCTCGACAAG
  GCATCCATCATTCGACTTACAATTAGCTATCTGAAAATGAGGGACTTTGCTAACCAGGGG
  GACCCTCCGTGGAACTTGCGAATGGAAGGCCCTCCACCTAACACATCAGTAAAAGGGATA
  CAAATGTGGAAATCTGAACTCTGCATGAGAAAGACACCATGTGAAGGTGCACAGCGAAGG
  AGAAGCCCCAGTGCACTAGCCATTGAAGTATTTGAAGCACATTTGGGAAGCCACATTTTG
  CAGTCCCTGGATGGCTTTGTATTTGCACTAAATCAGGAAGGAAAATTTTTGTACATTTCC
  GAAACAGTCTCCATCTACCTAGGCCTCTCACAAGTGGAGCTGACAGGCAGCAGTGTCTTT
  GACTATGTCCACCCCGGAGATCACGTGGAGATGGCTGAGCAGCTGGGCATGAAGCTCCCC
  CCTGGGCGGGGTCTCCTGTCACAGGGCACTGCTGAGGACGGAGCCAGCTCAGCATCTTCC
  TCCTCTCAGTCGGAGACCCCCGAGCCAGTGGAGTCAACCAGCCCCAGTCTGCTAACCACT
  GACAACACTCTTGAGCGTTCCTTTTTCATCCGAATGAAATCTACTCTGACCAAACGCGGT
  GTGCACATCAAATCATCAGGATATAAGGTGATTCACATAACAGGCCGGCTACGCCTGAGA
  GTGTCGCTGTCCCACGGGAGGACCGTCCCCAGCCAAATCATGGGTCTCGTGGTTGTTGCG
  CATGCCTTGCCTCCCCCTACGATCAATGAAGTCAGAATTGACTGCCATATGTTCGTCACT
  CGAGTAAATATGGACCTCAATATCATTTACTGTGAAAATAGGATTAGTGATTATATGGAT
  CTGACCCCTGTAGATATCGTAGGGAAGAGATGCTACCACTTCATCCATGCTGAAGACGTG
  GAGGGCATCAGGCACAGTCACTTGGACTTGCTGAATAAGGGTCAGTGTGTGACAAAGTAC
  TATCGCTGGATGCAGAAGAACGGAGGATATATTTGGATACAGTCCAGTGCCACCATAGCT
  ATTAATGCCAAGAATGCAAATGAAAAGAATATCATCTGGGTGAATTACCTTCTTAGCAAT
  CCTGAGTACAAGGACACACCCATGGACATCGCACAGCTCCCCCATCTGCCGGAGAAAACT
  TCCGAATCCTCGGAGACATCCGACTCTGAGTCAGACTCTAAAGACACCTCAGAGGACAAC
  GAGAACTCCAAGTCCGACGAGAAGGGGAACCAGTCCGAGAACAGCGAAGACCCGGAGCCC
  GACCGGAAGAAGTCGGGCAACGCGTGTGACAACGACATGAACTGCAACGACGACGGCCAC
  AGCTCCAGTAACCCGGACAGCCGCGACAGCGACGACAGCTTCGAGCACTCGGACTTTGAG
  AACCCCAAGGCGGGCGAGGACGGCTTCGGTGCTCTGGGCGCGATGCAGATCAAGGTGGAG
  CGCTACGTGGAGAGCGAGTCGGACCTGCGGCTGCAGAACTGCGAGTCACTCACGTCCGAC
  AGCGCCAAGGACTCGGACAGCGCAGGCGAGGCGGGCGCGCAGGCCTCCAGCAAGCACCAG
  AAGCGCAAGAAAAGGCGGAAACGGCAAAAGGGCGGCAGCGCCAGCCGCCGGCGCCTGTCC
  AGCGCGTCGAGCCCAGGCGGCCTGGACGCGGGCCTGGTGGAGCCCCCGCGGCTGCTGTCC
  TCCCCCAACAGTGCCTCGGTGCTCAAGATCAAGACGGAGATCTCAGAACCCATCAATTTC
  GACAATGACAGCAGCATCTGGAACTACCCGCCCAACCGGGAGATCTCCAGGAACGAGTCC
  CCCTACAGCATGACCAAGCCCCCCAGCTCTGAGCACTTCCCGTCCCCGCAGGGCGGCGGC
  GGTGGGGGTGGCGGTGGCGGGGGGCTGCACGTGGCCATTCCCGACTCGGTCCTCACCCCG
  CCCGGCGCCGACGGCGCGGCCGCCCGCAAGACTCAGTTCGGCGCCTCGGCCACCGCGGCC
  CTGGCCCCCGTCGCCTCCGACCCGCTGTCACCCCCGCTCTCGGCGTCCCCGCGGGACAAG
  CACCCCGGGAACGGCGGCGGGGGCGGGGGCGGGGGCGGCGGCGCGGGGGGCGGCGGCCCC
  AGCGCGTCCAACTCCTTGCTGTACACTGGGGACCTGGAGGCGCTGCAGAGGTTGCAGGCG
  GGCAACGTCGTGCTCCCGCTGGTGCACAGGGTGACCGGGACCCTGGCCGCCACCAGCACG
  GCCGCGCAGAGGGTCTACACCACGGGCACCATCCGCTACGCGCCCGCCGAGGTGACCCTG
  GCCATGCAGAGCAACCTGCTGCCCAACGCGCACGCTGTTAACTTCGTGGACGTTAACAGC
  CCCGGCTTTGGCCTCGACCCCAAGACGCCCATGGAGATGCTCTACCACCACGTGCACCGG
  CTCAACATGTCAGGACCGTTCGGCGGCGCAGTGAGCGCAGCTAGCCTGACGCAGATGCCC
  GCCGGCAACGTGTTCACCACGGCCGAGGGACTCTTCTCCACGCTGCCCTTCCCCGTCTAC
  AGCAACGGCATCCACGCGGCACAGACTCTGGAGCGCAAGGAGGACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_173159 unedited
  TGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCCGCGCCGGGCATGCCTC
  GGGAGCCGGGGCGGCCCGGGCCGCGGGCGCTCTGCGGCGCATGGACGGCGGCGGCGCCGG
  GCGAGCAGCGGGAGGAGAAGGCGCAGGCGGCGGCGGAAGCGGCGACCCACGGCTGGGAGC
  ACCGGCGGCGCGAGGGGACGGCCGGCCGCCCGCGAGGCTCCGGCCCCACTACTTTTCCGT
  AGCCTCCCCACCTCAGCAGCACGGCCGCCGCCGCCGCCGCCGCCGCCGCCACGGCCACGG
  CCACGGCCCCGGCCACCGCCCGCCGGGCAGCCCAGAGCGCCGCGCACGGCCGCACTCTCC
  CGCCACCCCACGCACACGCACACCCCCGCCCGCCCACGCCCCCCACCCGGGAGGGGGGAG
  AGAGGCAAAAAGTAAGAGAGGAATAAAAATAGCAGGAAGATGGCGCCCACCAAGCCCAGC
  TTTCAGCAGGATTCTTCCATGCGAGAACGTTTACAAGCATTGAGAAAGGAGAAATCCCGA
  GATGCTGCTCGCTCCCGCCGGGGAAAAGAAAACTTTGAGTTCTATGAATTGGCCAAGTTG
  TTGCCTCTTCCTGCAGCCATTACCACCCAGCTCGACAAGGCATCCATTATTCGACTTACA
  ATTAGCTATCTTGAAATGAGGGACTTTGCTTACCACTGGGGACTCTTCGTGGAACTTGCT
  AATGGAAGGCCCTCCACCTTAACCATTAGTTAAAAGGGATACACATTGTGGTATATTTCA
  ACTCTGCCTTTAAAAACACCCAATGCGAAGTGTGTTAACCCGAAAGATAAGCCCCCCTGC
  ATTTTCCCCTGGCATCTTTTGAAGCTCATTTGTGAATCCACTTTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_173159 unedited
  NGGGGCCATTGGNNGATGGCACTTNCCAGGTCCAGNANAGCACTGGGGCAGGGTCACAGG
  GATGCCACCCGGGATCTGTTCAGGAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT
  TTTTTTTTTTTTTTTTTTTTTACTTAATGTGCAGTTTTCAGTTGCAGTTATCTGTCTGAA
  GCTTATTAACCCATTCTTTAGTTTTAAAACTTATTGGTTTCAACCCAGAAATAAGAACCA
  AAGGGAAAGAAATTCCATCAAATCAAACCAGTCCCCCCAAATACAACCTTCCTTTTTGTT
  TTAAGCAAGGAATGAAAAAAACCAAAAACATGTTAAATATTTTCCTTCTTTTACTCCGAA
  GTGTTATTGAAGTTGCAAAATTAGCCTCAGTTAGACTGAGTAAGGAAAACAAAAAGCTAA
  ACAAAAGGCAGTATGTACCTAAACTGCTCCTCAAATCAGTTTGATTGAGTTTTCCAGCAG
  CCCCTTTAAAAGGGGCTTTACTGACCCATTAAATTTAATGTGAGGCTATGTTTGTTAGTT
  GGGAGGTAAAAAATTTTAAGTCCTGCAGCAAACGTTAATGAGGGCTTTGTCTTAACTAAC
  CAAGGAGACTGCAGCAACGGACTCCAGACCAGGACAGAACACATTTTTTTTTTTTCCCCC
  AAAACCCAGCCCAGGAGCTGCATTTTGTATGAAGACATTACAGATTAATAAATGATAGCA
  CCATGGTTTTAGAAATTAAGTAATGTTTCAGGTATTAACATTTAGTCCGACTTTTTTTTT
  TTTAAACATTCTAGTCCCAGCCCAGAAATAAGTTTTAGAACCCAATTATTTTTATGGGCA
  AGTAAGAAAATTTTAAAATCTTAACGTCAAAAGAGATTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_173159
• ORF Size: 2763 bp
• Insert Size: 4750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There are two short (in-frame) deletions of 6bp and 9bp between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the deletions of 2 and 3 amino acids, respectively.

Reference Data

• RefSeq: NM_173159.1, NP_775182.1
• RefSeq Size: 2763
• RefSeq ORF: 2763
• Locus ID: 64067
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.