CCRL2 (NM_003965) Human Tagged ORF Clone

CAT#: RG218484

CCRL2 (GFP-tagged) - Human chemokine (C-C motif) receptor-like 2 (CCRL2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CCRL2
• Synonyms: ACKR5; CKRX; CRAM; CRAM-A; CRAM-B; HCR
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG218484 representing NM_003965
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCAATTACACGCTGGCACCAGAGGATGAATATGATGTCCTCATAGAAGGTGAACTGGAGAGCGATG
  AGGCAGAGCAATGTGACAAGTATGACGCCCAGGCACTCTCAGCCCAGCTGGTGCCATCACTCTGCTCTGC
  TGTGTTTGTGATCGGTGTCCTGGACAATCTCCTGGTTGTGCTTATCCTGGTAAAATATAAAGGACTCAAA
  CGCGTGGAAAATATCTATCTTCTAAACTTGGCAGTTTCTAACTTGTGTTTCTTGCTTACCCTGCCCTTCT
  GGGCTCATGCTGGGGGCGATCCCATGTGTAAAATTCTCATTGGACTGTACTTCGTGGGCCTGTACAGTGA
  GACATTTTTCAATTGCCTTCTGACTGTGCAAAGGTACCTAGTGTTTTTGCACAAGGGAAACTTTTTCTCA
  GCCAGGAGGAGGGTGCCCTGTGGCATCATTACAAGTGTCCTGGCATGGGTAACAGCCATTCTGGCCACTT
  TGCCTGAATTCGTGGTTTATAAACCTCAGATGGAAGACCAGAAATACAAGTGTGCATTTAGCAGAACTCC
  CTTCCTGCCAGCTGATGAGACATTCTGGAAGCATTTTCTGACTTTAAAAATGAACATTTCGGTTCTTGTC
  CTCCCCCTATTTATTTTTACATTTCTCTATGTGCAAATGAGAAAAACACTAAGGTTCAGGGAGCAGAGGT
  ATAGCCTTTTCAAGCTTGTTTTTGCCATAATGGTAGTCTTCCTTCTGATGTGGGCGCCCTACAATATTGC
  ATTTTTCCTGTCCACTTTCAAAGAACACTTCTCCCTGAGTGACTGCAAGAGCAGCTACAATCTGGACAAA
  AGTGTTCACATCACTAAACTCATCGCCACCACCCACTGCTGCATCAACCCTCTCCTGTATGCGTTTCTTG
  ATGGGACATTTAGCAAATACCTCTGCCGCTGTTTCCATCTGCGTAGTAACACCCCACTTCAACCCAGGGG
  GCAGTCTGCACAAGGCACATCGAGGGAAGAACCTGACCATTCCACCGAAGTG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG218484 representing NM_003965
  Red=Cloning site Green=Tags(s)
  
  MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLK
  RVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFS
  ARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLV
  LPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDK
  SVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
  
  SGPTRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_003965
• ORF Size: 1032 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003965.4, NP_003956.2
• RefSeq Size: 1745
• RefSeq ORF: 1035
• Locus ID: 9034
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]