Bcl2 Binding component 3 (BBC3) (NM_001127240) Human Tagged ORF Clone
CAT#: RG225345
- TrueORF®
BBC3 (GFP-tagged) - Human BCL2 binding component 3 (BBC3), transcript variant 1
"NM_001127240" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | BBC3 |
Synonyms | JFY-1; JFY1; PUMA |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG225345 representing NM_001127240
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAATTTGGCATGGGGTCTGCCCAGGCATGTCCATGCCAGGTGCCCAGGGCTGCTTCCACGACGTGGG TCCCCTGCCAGATTTGTGGCCCCAGGGAGCGCCATGGCCCGCGCACGCCAGGAGGGCAGCTCCCCGGAGC CCGTAGAGGGCCTGGCCCGCGACGGCCCGCGCCCCTTCCCGCTCGGCCGCCTGGTGCCCTCGGCAGTGTC CTGCGGCCTCTGCGAGCCCGGCCTGGCTGCCGCCCCCGCCGCCCCCACCCTGCTGCCCGCTGCCTACCTC TGCGCCCCCACCGCCCCACCCGCCGTCACCGCCGCCCTGGGGGGTTCCCGCTGGCCTGGGGGTCCCCGCA GCCGGCCCCGAGGCCCGCGCCCGGACGGTCCTCAGCCCTCGCTCTCGCTGGCGGAGCAGCACCTGGAGTC GCCCGTGCCCAGCGCCCCGGGGGCTCTGGCGGGCGGTCCCACCCAGGCGGCCCCGGGAGTCCGCGGGGAG GAGGAACAGTGGGCCCGGGAGATCGGGGCCCAGCTGCGGCGGATGGCGGACGACCTCAACGCACAGTACG AGCGGCGGAGACAAGAGGAGCAGCAGCGGCACCGCCCCTCACCCTGGAGGGTCCTGTACAATCTCATCAT GGGACTCCTGCCCTTACCCAGGGGCCACAGAGCCCCCGAGATGGAGCCCAATTAGGTGCCTGCACCCGCC CGGTGGACGTCAGGGACTCGGGGGGCAGGCCCCTCCCACCTCCTGACACCCTGGCCAGCGCGGGGGACTT TCTCTGCACCATG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG225345 representing NM_001127240
Red=Cloning site Green=Tags(s) MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSV LRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGV ARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHH GTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPDTLASAGDFLCTM TRTRRLE - GFP Tag - V |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001127240 |
ORF Size | 783 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001127240.1, NP_001120712.1 |
RefSeq Size | 1827 |
RefSeq ORF | 786 |
Locus ID | 27113 |
Protein Families | Druggable Genome |
Protein Pathways | Huntington's disease, p53 signaling pathway |
Gene Summary | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC322931 | BBC3 (untagged)-Human BCL2 binding component 3 (BBC3), transcript variant 1 |
USD 420.00 |
|
RC225345 | BBC3 (Myc-DDK-tagged)-Human BCL2 binding component 3 (BBC3), transcript variant 1 |
USD 420.00 |
|
RC225345L1 | Lenti ORF clone of Human BCL2 binding component 3 (BBC3), transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
|
RC225345L2 | Lenti ORF clone of Human BCL2 binding component 3 (BBC3), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC225345L3 | Lenti ORF clone of Human BCL2 binding component 3 (BBC3), transcript variant 1, Myc-DDK-tagged |
USD 620.00 |
|
RC225345L4 | Lenti ORF clone of Human BCL2 binding component 3 (BBC3), transcript variant 1, mGFP tagged |
USD 620.00 |
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