SV2B (NM_001167580) Human Tagged ORF Clone

CAT#: RG230240

SV2B (GFP-tagged) - Human synaptic vesicle glycoprotein 2B (SV2B), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: SV2B
• Synonyms: HsT19680
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230240 representing NM_001167580
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATAGTCTACTTGGGAATGATGGCGGGCGCCTTCATCCTGGGAGGCCTGGCTGATAAGCTGGGAAGGA
  AGCGAGTCCTCAGCATGTCTCTGGCCGTCAATGCCTCCTTCGCCTCCCTCTCTTCCTTCGTGCAGGGATA
  TGGAGCCTTCCTCTTCTGCCGACTCATCTCAGGCATCGGTATTGGGGGTGCTCTACCGATTGTTTTTGCC
  TATTTTTCTGAATTCTTGTCTCGGGAGAAGCGAGGAGAACACCTCAGTTGGCTGGGCATCTTCTGGATGA
  CTGGGGGCCTGTACGCATCTGCCATGGCCTGGAGCATCATCCCACACTATGGCTGGGGCTTCAGCATGGG
  GACCAATTACCACTTCCATAGCTGGAGAGTGTTTGTCATCGTCTGTGCTCTGCCCTGCACCGTGTCCATG
  GTGGCCCTGAAGTTCATGCCAGAGAGCCCAAGGTTTCTGCTAGAGATGGGCAAACATGATGAAGCCTGGA
  TGATTCTCAAGCAAGTCCATGACACCAACATGAGAGCTAAGGGGACCCCAGAGAAAGTGTTCACGGTTTC
  CAACATCAAAACTCCCAAGCAAATGGATGAATTCATTGAGATCCAAAGTTCAACAGGAACCTGGTACCAG
  CGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGGTCTGGGATAATGCCCTGTACTGTGTGATGGGGC
  CCTACAGAATGAATACACTGATTCTGGCCGTGGTTTGGTTTGCCATGGCATTCAGTTACTATGGACTGAC
  AGTTTGGTTTCCTGATATGATCCGCTATTTTCAAGATGAAGAATACAAGTCTAAAATGAAGGTGTTTTTT
  GGTGAGCATGTGTACGGCGCCACAATCAACTTCACGATGGAAAATCAGATCCACCAACATGGGAAACTTG
  TGAATGATAAGTTCACAAGAATGTACTTTAAACATGTACTCTTTGAGGACACATTCTTTGACGAGTGCTA
  TTTTGAAGACGTAACATCAACAGATACCTACTTCAAAAATTGTACCATTGAATCAACCATCTTTTACAAC
  ACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGTTTATCAACTCCACCTTCCTGGAGCAGAAGGAGG
  GCTGCCACATGGACTTGGAGCAAGATAATGACTTCCTGATTTACCTCGTCAGCTTCCTGGGCAGCCTGTC
  TGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATGGATAGAATTGGAAGGCTCAAGATGATTGGTGGC
  TCCATGCTAATCTCTGCAGTCTGCTGCTTCTTCCTGTTTTTTGGCAACAGTGAGTCTGCAATGATCGGCT
  GGCAGTGCCTGTTCTGTGGGACAAGCATTGCAGCCTGGAATGCTCTGGATGTGATCACAGTGGAGCTGTA
  TCCCACCAACCAGAGAGCAACAGCCTTCGGCATTCTCAATGGATTATGCAAATTTGGCGCCATCCTGGGA
  AACACCATCTTTGCTTCTTTTGTTGGGATAACCAAAGTGGTCCCCATCCTTCTGGCTGCTGCTTCTCTGG
  TTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGACTCGAGAACAGGTCCTGATG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230240 representing NM_001167580
  Red=Cloning site Green=Tags(s)
  
  MIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFA
  YFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSM
  VALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQ
  RWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFF
  GEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYN
  TDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGG
  SMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILG
  NTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001167580
• ORF Size: 1596 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001167580.1, NP_001161052.1
• RefSeq Size: 10788
• RefSeq ORF: 1599
• Locus ID: 9899
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: ECM-receptor interaction
• Gene Summary: This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016]