SV2B (NM_001167580) Human Untagged Clone

CAT#: SC328878

SV2B (untagged)-Human synaptic vesicle glycoprotein 2B (SV2B) transcript variant 2


  "NM_001167580" in other vectors (6)

Reconstitution Protocol

USD 900.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SV2B
Synonyms HsT19680
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001167580, the custom clone sequence may differ by one or more nucleotides


ATGATAGTCTACTTGGGAATGATGGCGGGCGCCTTCATCCTGGGAGGCCTGGCTGATAAGCTGGGAAGGA
AGCGAGTCCTCAGCATGTCTCTGGCCGTCAATGCCTCCTTCGCCTCCCTCTCTTCCTTCGTGCAGGGATA
TGGAGCCTTCCTCTTCTGCCGACTCATCTCAGGCATCGGTATTGGGGGTGCTCTACCGATTGTTTTTGCC
TATTTTTCTGAATTCTTGTCTCGGGAGAAGCGAGGAGAACACCTCAGTTGGCTGGGCATCTTCTGGATGA
CTGGGGGCCTGTACGCATCTGCCATGGCCTGGAGCATCATCCCACACTATGGCTGGGGCTTCAGCATGGG
GACCAATTACCACTTCCATAGCTGGAGAGTGTTTGTCATCGTCTGTGCTCTGCCCTGCACCGTGTCCATG
GTGGCCCTGAAGTTCATGCCAGAGAGCCCAAGGTTTCTGCTAGAGATGGGCAAACATGATGAAGCCTGGA
TGATTCTCAAGCAAGTCCATGACACCAACATGAGAGCTAAGGGGACCCCAGAGAAAGTGTTCACGGTTTC
CAACATCAAAACTCCCAAGCAAATGGATGAATTCATTGAGATCCAAAGTTCAACAGGAACCTGGTACCAG
CGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGGTCTGGGATAATGCCCTGTACTGTGTGATGGGGC
CCTACAGAATGAATACACTGATTCTGGCCGTGGTTTGGTTTGCCATGGCATTCAGTTACTATGGACTGAC
AGTTTGGTTTCCTGATATGATCCGCTATTTTCAAGATGAAGAATACAAGTCTAAAATGAAGGTGTTTTTT
GGTGAGCATGTGTACGGCGCCACAATCAACTTCACGATGGAAAATCAGATCCACCAACATGGGAAACTTG
TGAATGATAAGTTCACAAGAATGTACTTTAAACATGTACTCTTTGAGGACACATTCTTTGACGAGTGCTA
TTTTGAAGACGTAACATCAACAGATACCTACTTCAAAAATTGTACCATTGAATCAACCATCTTTTACAAC
ACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGTTTATCAACTCCACCTTCCTGGAGCAGAAGGAGG
GCTGCCACATGGACTTGGAGCAAGATAATGACTTCCTGATTTACCTCGTCAGCTTCCTGGGCAGCCTGTC
TGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATGGATAGAATTGGAAGGCTCAAGATGATTGGTGGC
TCCATGCTAATCTCTGCAGTCTGCTGCTTCTTCCTGTTTTTTGGCAACAGTGAGTCTGCAATGATCGGCT
GGCAGTGCCTGTTCTGTGGGACAAGCATTGCAGCCTGGAATGCTCTGGATGTGATCACAGTGGAGCTGTA
TCCCACCAACCAGAGAGCAACAGCCTTCGGCATTCTCAATGGATTATGCAAATTTGGCGCCATCCTGGGA
AACACCATCTTTGCTTCTTTTGTTGGGATAACCAAAGTGGTCCCCATCCTTCTGGCTGCTGCTTCTCTGG
TTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGACTCGAGAACAGGTCCTGATGTGA


Restriction Sites SgfI-MluI     
ACCN NM_001167580
ORF Size 1599 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_001167580.1, NP_001161052.1
RefSeq Size 10788
RefSeq ORF 1599
Locus ID 9899
Protein Families Secreted Protein, Transmembrane
Protein Pathways ECM-receptor interaction
Gene Summary This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016]
Transcript Variant: This variant (2) lacks two internal exons in the 5' region, as compared to variant 1. This results in a downstream in-frame AUG start codon and a shorter isoform (2), as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.