Angiomotin like 1 (AMOTL1) (NM_130847) Human Untagged Clone

CAT#: SC100236

AMOTL1 (untagged)-Human angiomotin like 1 (AMOTL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMOTL1
• Synonyms: JEAP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100236 sequence for NM_130847 edited (data generated by NextGen Sequencing)
  ATGTGGAGGGCAAAGTTGCGCCGGGGAACTTGTGAGCCTGCGGTGAAAGGGTCCCCTTCT
  GCTTGTTATAGCCCCAGTAGTCCTGTCCAGGTTCTAGAAGACTCCACCTACTTTTCCCCA
  GACTTTCAGCTCTATTCTGGGAGGCATGAAACATCTGCTTTGACGGTGGAGGCAACCAGT
  AGCATCAGGGAAAAAGTTGTTGAAGATCCTCTTTGTAACTTCCACTCCCCAAACTTCCTG
  AGGATCTCAGAGGTGGAAATGAGAGGTTCCGAGGATGCGGCAGCTGGAACAGTATTGCAG
  CGGCTGATCCAGGAACAACTGCGGTATGGCACCCCAACCGAGAACATGAACTTGCTGGCC
  ATTCAGCACCAGGCCACAGGGAGTGCAGGACCAGCCCATCCTACAAACAACTTTTCTTCC
  ACGGAAAACCTCACTCAAGAAGACCCACAAATGGTCTACCAGTCAGCACGCCAAGAACCG
  CAGGGTCAAGAACACCAGGTGGACAATACGGTGATGGAGAAACAGGTCCGGTCCACGCAG
  CCTCAGCAGAACAACGAGGAACTGCCCACTTACGAGGAGGCCAAAGCACAGTCGCAGTTC
  TTCAGGGGGCAGCAGCAGCAGCAACAGCAGCAGGGGGCGGTGGGCCATGGTTACTACATG
  GCAGGGGGCACCAGTCAGAAGTCCCGAACTGAGGGGAGGCCCACTGTGAACCGTGCCAAC
  AGTGGACAGGCGCATAAGGACGAGGCGCTGAAGGAACTGAAGCAGGGCCACGTCCGCTCG
  CTCAGCGAGAGAATCATGCAGCTGTCCCTGGAGAGGAATGGGGCCAAGCAACACCTTCCC
  GGCTCGGGGAATGGAAAGGGCTTCAAAGTAGGAGGGGGGCCCTCCCCTGCCCAGCCTGCA
  GGTAAAGTGCTGGACCCTCGGGGTCCTCCACCTGAGTACCCCTTCAAGACCAAGCAAATG
  ATGTCCCCAGTCAGCAAGACCCAGGAGCACGGACTTTTTTATGGTGACCAGCACCCCGGG
  ATGCTCCACGAGATGGTCAAGCCCTACCCTGCTCCTCAGCCTGTGAGAACAGATGTGGCC
  GTCCTGCGGTACCAGCCACCCCCTGAGTATGGGGTAACGAGCCGCCCATGCCAACTTCCG
  TTCCCATCAACCATGCAGCAGCACAGCCCCATGTCCTCCCAGACCTCTTCCGCCAGCGGG
  CCACTGCACTCTGTCTCCCTGCCGCTTCCACTCCCGATGGCCCTGGGTGCTCCACAGCCC
  CCGCCTGCCGCCTCCCCCAGCCAGCAGCTTGGTCCAGATGCCTTTGCGATTGTGGAGCGA
  GCCCAGCAAATGGTGGAGATATTAACAGAGGAGAACCGGGTGCTTCACCAGGAACTTCAG
  GGTTACTACGACAATGCCGACAAGCTCCACAAGTTTGAAAAAGAACTTCAGAGAATTTCG
  GAAGCCTATGAAAGTCTGGTCAAGTCTACCACCAAGCGAGAATCGCTGGACAAGGCCATG
  AGAAACAAATTGGAAGGCGAGATTAGAAGACTTCATGATTTCAACAGAGACCTCCGAGAT
  CGACTAGAGACTGCTAACAGGCAACTATCCAGCAGGGAATACGAAGGGCATGAAGACAAA
  GCTGCAGAGGGGCATTATGCTTCCCAGAACAAAGAATTCTTGAAGGAAAAGGAGAAATTA
  GAAATGGAGTTAGCAGCAGTGCGGACTGCAAGTGAGGACCATCGGAGACACATCGAGATC
  CTGGACCAGGCTTTGAGCAACGCCCAGGCCAGGGTCATCAAGCTGGAAGAGGAGTTACGA
  GAGAAGCAAGCATATGTTGAGAAAGTTGAGAAGCTGCAGCAGGCCCTGACCCAGCTGCAG
  TCTGCATGTGAGAAGCGAGAACAGATGGAGCGGAGACTGCGGACTTGGCTGGAGAGAGAG
  CTGGATGCACTGAGAACCCAGCAGAAACATGGAAATGGCCAGCCAGCCAACATGCCGGAA
  TACAATGCCCCAGCCCTCCTGGAACTTGTGCGGGAGAAGGAGGAGCGGATCCTGGCCCTG
  GAGGCCGACATGACAAAGTGGGAGCAGAAGTACCTGGAGGAGAGCACCATCCGACACTTT
  GCCATGAATGCCGCAGCCACTGCAGCAGCTGAGAGGGACACCACGATCATCAACCACTCA
  CGGAATGGCAGCTACGGAGAGAGCTCGCTGGAGGCCCACATCTGGCAAGAGGAGGAGGAG
  GTGGTGCAGGCCAACAGAAGGTGTCAGGACATGGAATACACTATTAAAAATCTCCATGCC
  AAAATCATAGAGAAAGATGCTATGATTAAGGTCCTGCAGCAGCGATCTCGTAAAGATGCC
  GGGAAGACAGACTCCTCCAGCCTACGTCCTGCCCGCTCCGTTCCATCCATAGCAGCAGCT
  ACTGGGACACACTCTCGCCAGACCTCTCTTACCAGCAGCCAGCTGGCTGAGGAAAAGAAG
  GAAGAGAAGACCTGGAAGGGGAGCATAGGATTGCTGCTGGGGAAGGAGCACCATGAGCAT
  GCCTCTGCCCCACTGCTGCCACCCCCACCCACCTCAGCACTGTCCTCCATAGCCTCCACT
  ACGGCAGCCAGCAGTGCCCACGCCAAGACAGGCAGCAAGGACAGCAGCACACAGACTGAC
  AAGAGTGCCGAGCTCTTCTGGCCCAGCATGGCCTCCCTTCCCAGCCGCGGCCGGCTGAGC
  ACGACCCCTGCTCACAGCCCCGTCCTGAAACACCCAGCGGCCAAAGGGACCGCAGAGAAA
  CTGGAGAACTCTCCTGGCCATGGGAAGTCGCCTGACCACAGAGGCCGGGTCAGCAGCTTG
  CTGCACAAGCCCGAGTTCCCTGATGGAGAGATGATGGAAGTCCTCATCTAA
  
  Clone variation with respect to NM_130847.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130847 unedited
  TCAACATTTGTAATACGACTCACTATAGGGCGGCCGCGCAGCGGTTGTCGGGTTTGGGGC
  TGGAGGTGAAGCCCTGTGTGAATGGGGTTGATTGTCCGGCGCCACTTCCCCGCGCTGCCC
  GGCAGCCGTCTTCCCCAGCCGAGGGACTGAACTAGCCATGATCGCCTCATGTGGAGGGCA
  AAGTTGCGCCGGGGAACTTGTGAGCCTGCGGTGAAAGGGTCCCCTTCTGCTTGTTATAGC
  CCCAGTAGTCCTGTCCAGGTTCTAGAAGACTCCACCTACTTTTCCCCAGACTTTCAGCTC
  TATTCTGGGAGGCATGAAACATCTGCTTTGACGGTGGAGGCAACCAGTAGCATCAGGGAA
  AAAGTTGTTGAAGATCCTCTTTGTAACTTCCACTCCCCAAACTTCCTGAGGATCTCAGAG
  GTGGAAATGAGAGGTTCCGAGGATGCGGCAGCTGGAACAGTATTGCAGCGGCTGATCCAG
  GAACAACTGCGGTATGGCACCCCAACCGAGAACATGAACTTGCTGGCCATTCAGCACCAG
  GCCACAGGGAGTGCAGGACCAGCCCATCCTACAAACAACTTTTCTTCCACGGAAAACCTC
  ACTCAAGAAGACCCACAAATGGTCTACCAGTCAGCACGCCAAGAACCGCAGGGTCAAGAA
  CACCAGGTTGGACAATACGGTGATGGAGAAACAGGTTCCGTCCACGCAGCCTCAGCAGAA
  CAACGAAGAACTGCCCACTTACGAGGAGGCCAAAGCACAGTCGCAGTTTTTCAAGGGGCA
  GCAGCATCACCACAGCAGCATGGGGCCGTGGGCCATGGTTACTACATGGCAGGGGGCACC
  ATTCAAAATTCCCGACCTGAGGGATGCCCCTGTGTACCGTGCCACCGGGACAAGCGCTTA
  AGACCAGCGCTTAAGAACTAATCAGGCCCTTCCGTTCGTCACGAGAGATATGCACTGCCC
  TGAGAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_130847 unedited
  NNNGGGTATAGCTATGNAACCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGGGATTCCCAGGGTGATCC
  CCATTTGGGTTTATCTGTTTATAAACAAAAAAAGGGGGGACCCCAGCCCCCCCCAAAAAA
  ACATTTTTTGGACAAAGAAAAAATCAATTTCCCATTTTTTAAATTTGTTTGGAAAACTAC
  ACCCCTCTTTTTTTTTTCACCATGTGTAAAAAAAACCCTCGCAATTTCTTTTATCTTCAA
  TCATGGAGTTTTTGGGGTTAAAAATTATAAAAAGGGTTCTTATGAATCTGAAAACTTTAT
  CAATTCAAAACATTCCTGAATTCCCATCTACAACCCTTTAAGGCTTTTTTCTTTTTCTGC
  CGCTTTCCTTGGTTGGCAATGTTCTGGACTGAAATTCCCCAAGGGTGGGCGTTAAATGAA
  GACTTTCCTCATCTCTCCCTCAAGGAACTCGGGCTTGTGCAACAAGCTGCTGACCCCGCC
  CCTGTGGTCAAGCGAATTTCCCTGGGCCGGAAAATTTTCCAGTTTTTCTGCGGGCCCTTT
  TGCCCCTGGGTGTTTTAAGACCGGGCTTTGAACAAGGGTTCTGCTCAACCCGCCGCGGCT
  TGGAAAGGAAGCCCTGCTTGGCCAAAAAAACTCGGCACCCTTGTCAATCCGTGTGCCGCT
  GGCCCTGCTGCCCGTCTTGGCGTGGGCACTGGTGGCTGCCCTAATGGAAGCCATTGAAGA
  CAATGCCTTAGTGGGTTGGGGGGGGGCCAACCATGGGGGCACAAGGCATTCCTCTGGGTG
  GTTTCCTTTCCCCAGAAACCATCCTATAGCTCCCTTTCAGGTTTTTTCCTTCCTTTTTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130847
• ORF Size: 2871 bp
• Insert Size: 4000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_130847.1, NP_570899.1
• RefSeq Size: 5299
• RefSeq ORF: 2871
• Locus ID: 154810
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).