PMPCA (NM_015160) Human Untagged Clone

CAT#: SC100435

PMPCA (untagged)-Human peptidase (mitochondrial processing) alpha (PMPCA), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PMPCA
• Synonyms: Alpha-MPP; CLA1; CPD3; INPP5E; P-55; SCAR2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100435 sequence for NM_015160 edited (data generated by NextGen Sequencing)
  ATGGCGGCTGTGGTGCTGGCGGCGACGCGGTTGCTGCGGGGCTCGGGTTCTTGGGGCTGT
  TCGCGGCTGAGGTTTGGACCTCCTGCGTACAGACGGTTTAGTAGTGGTGGTGCCTATCCC
  AACATCCCCCTCTCTTCTCCCTTACCTGGAGTACCCAAGCCTGTTTTTGCTACAGTTGAT
  GGACAGGAAAAGTTTGAAACCAAAGTAACCACATTGGATAATGGGCTTCGCGTGGCATCT
  CAGAATAAGTTTGGACAGTTTTGTACAGTAGGAATTCTTATCAATTCAGGATCGAGATAT
  GAAGCGAAATACCTTAGTGGAATTGCTCACTTTTTGGAAAAATTGGCATTTTCGTCTACT
  GCTCGATTTGACAGCAAAGATGAAATTCTGCTTACGTTGGAAAAGCATGGGGGTATCTGT
  TACTGCCAGACATCAAGAGACACCACCATGTATGCTGTGTCTGCTGATAGCAAAGGCTTG
  GACACGGTGGTTGCCTTACTGGCTGATGTGGTTCTGCAGCCCCGGCTAACAGATGAAGAA
  GTCGAGATGACGCGGATGGCGGTCCAGTTTGAGCTGGAGGACCTGAACCTGCGGCCTGAC
  CCAGAGCCACTTCTCACCGAGATGATTCATGAAGCGGCTTACAGGGAGAACACAGTTGGC
  CTCCACCGTTTCTGCCCCACAGAAAACGTAGCAAAGATCAATCGAGAGGTGCTGCATTCC
  TACCTGAGGAACTACTACACTCCCGACCGCATGGTGCTGGCCGGCGTGGGCGTGGAGCAC
  GAGCATCTGGTGGACTGTGCCCGGAAGTACCTCCTGGGGGTCCAGCCGGCCTGGGGGAGC
  GCAGAGGCCGTGGATATTGACAGATCTGTGGCCCAGTACACTGGGGGGATTGCCAAGCTA
  GAAAGAGACATGTCCAATGTCAGCCTGGGCCCGACCCCCATCCCCGAGCTCACGCACATC
  ATGGTTGGACTGGAGAGCTGCTCCTTCCTGGAGGAGGACTTCATCCCCTTTGCAGTGTTG
  AACATGATGATGGGCGGAGGTGGCTCCTTCTCGGCTGGTGGGCCCGGCAAGGGCATGTTC
  TCCAGGCTCTACCTCAACGTGCTCAACAGGCACCACTGGATGTATAACGCGACCTCCTAC
  CACCACAGCTACGAGGACACTGGCCTCCTTTGCATCCATGCCAGCGCCGACCCAAGACAG
  GTTCGAGAAATGGTAGAAATCATCACAAAGGAGTTTATTTTAATGGGCGGAACCGTGGAC
  ACGGTGGAGCTGGAACGAGCCAAGACGCAGCTGACATCAATGCTCATGATGAACCTGGAA
  TCCAGGCCTGTGATCTTCGAGGATGTGGGGAGGCAGGTGCTGGCCACTCGCTCCAGAAAG
  CTGCCGCACGAGCTGTGCACGCTCATCCGCAACGTGAAGCCGGAAGATGTGAAGAGAGTC
  GCTTCTAAGATGCTCCGAGGGAAGCCGGCAGTGGCCGCCCTGGGTGACCTGACTGACCTG
  CCCACGTATGAGCACATCCAGACCGCCCTGTCGAGTAAGGACGGGCGCCTGCCCAGGACG
  TACCGGCTCTTCCGGTAG
  
  Clone variation with respect to NM_015160.1
  421 g=>t;702 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015160 unedited
  TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGCAAGATGGCGGCTG
  TGGTGCTGGCGGCGACGCGGTTGCTGCGGGGCTCGGGTTCTTGGGGCTGTTCGCGGCTGA
  GGTTTGGACCTCCTGCGTACAGACGGTTTAGTAGTGGTGGTGCCTATCCCAACATCCCCC
  TCTCTTCTCCCTTACCTGGAGTACCCAAGCCTGTTTTTGCTACAGTTGATGGACAGGAAA
  AGTTTGAAACCAAAGTAACCACATTGGATAATGGGCTTCGCGTGGCATCTCAGAATAAGT
  TTGGACAGTTTTGTACAGTAGGAATTCTTATCAATTCAGGATCGAGATATGAAGCGAAAT
  ACCTTAGTGGAATTGCTCACTTTTTGGAAAAATTGGCATTTTCGTCTACTGCTCGATTTG
  ACAGCAAAGATGAAATTCTGCTTACGTTGGAAAAGCATGGGGGTATCTGTTACTGCCAGA
  CATCAAGAGACACCACCATGTATGCTGTGTCTGCTGATAGCAAAGGCTTGGACACGGTGG
  TTGCCTTACTGGCTGATGTGGTTCTGCAGCCCCGGCTAACAGATGAAGAAGTCGAGATGA
  CGCGGATGGCGGTCCAGTTTGAGCTGGAGGACCTGAACCTGCGGCCTGACCCAGAGCCAC
  TTCTCACCGAGATGATTCATGAAGCGGCTTACAGGGAGAACACAGTTGGCCTNCACCGTT
  TCTGCCCCACAGAANACGTAGCANAGATCAATCGAGAGGTGCTGCATTCCTACCTNGAGA
  ACTACTACACTCCCGACCGCATGGTGCTGNCCNGCGTGGGCGTGNAGACGAGCATCTGGT
  GGACTGTGCCCGGAAGTCCCTNCTGGGGTCCAGCCNGNCTGNGGGACGCANAGCCGTGNT
  ATTGACAGACTGTGCCCATACCTGGGGGGGATGCAGCTAGAGAGACTGTCATGTCAGCTG
  GCCCGACCCATNCCGACTCGCCANATGGTGGACTGAACTGCTCCCTGAGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015160 unedited
  GTACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTAAGAAAGATGCCGC
  TCTTTATTACCAGGGAAGCTGTGTGCACGCGCGTGGAGCGCGCTCCTTGGAGCTGACCGG
  GCCCTTACCTTCTCCTGCTTGTCAGAGGTGAGTCCTGGTACCCAGCACGGTGGCCTCTGG
  GAGGCTCTGATAGGTCAGCCTTTGCTGCCTCCCAGCTCAGGGCTCCTCCAAGGAACCTGC
  GGGGCCCCATGTGCCCACAGCCCGAGGAGGGAAGCACCGACCGCCCTCCTCGTGGCACGC
  TGCACTCCAGCGCTGGGCACTTCACCTGCTTCCTGGCTTGCGGTGGTCAGGCTCGATACT
  GACTCCACTGATCGGCACATTGAGTTCCGAAAGAATGCAAACCGCGTGGGTGCTGTGGCG
  ACATTGTTTGCACCGTTTATACAACCAGACAGCTTTTTAGACTAAATTCGTGTCCAAACT
  AACACGCACGGGAACGGGCTCCAGCTGCAGCTCCCTGGGTCTGTCAGGCCGGGGAGCGGT
  TCTACCGGAAGAGCCGGTACGTCCTGGGCAGGCGCCCGTCCTTACTCGACAGGGCGGTCT
  GGATGTGCTCATACGTGGGCAGGTCAGTCAGGTCACCCAGGGGCGGCCACTGCCGGCTTC
  CCTCGGAGCATCTTAGAAGCGACTCTCTTCACATCTTCCGGGCTCACGTTTGCGATGAGC
  GTGCACAGCTCGTGCGGGAGCTTTCTGGAGCGAGTGGCCAGCACCTGCCTCCCCAATCCT
  CGAAGATAACAGGCCTGGATTCAGGTTCATCATGAGCATTGATGTCAGCTGCGTCTGGCC
  TCGTTCCAGCTTACCCGGGTCCCGGGTCCGCCCATAAAATAAACCCCTTGGGAAGAATCT
  TACCATTTTCCAACCTGCTTTGGTCCGCCCTGGCCTGATACCAAGAAGCCCTGTCCTCTT
  ACTTGGTGGTAGGAGGCCCCGTTATCATCCGGGGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015160
• ORF Size: 1578 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015160.1, NP_055975.1
• RefSeq Size: 2097
• RefSeq ORF: 1578
• Locus ID: 23203
• Domains: Peptidase_M16, Peptidase_M16_C
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.