Myosin 1C (MYO1C) (NM_033375) Human Untagged Clone

CAT#: SC100515

MYO1C (untagged)-Human myosin IC (MYO1C), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MYO1C
• Synonyms: MMI-beta; MMIb; myr2; NMI
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100515 sequence for NM_033375 edited (data generated by NextGen Sequencing)
  ATGGAGAGTGCGCTCACCGCCCGTGACCGGGTGGGGGTGCAGGATTTCGTGCTGCTGGAG
  AACTTCACCAGCGAGGCCGCCTTCATCGAGAACCTGCGGCGGCGATTTCGGGAGAATCTC
  ATCTACACCTACATTGGCCCCGTCCTGGTCTCTGTCAATCCCTACCGGGACCTGCAGATC
  TACAGCCGGCAGCATATGGAGCGTTACCGTGGCGTCAGCTTCTATGAAGTGCCCCCTCAC
  CTGTTTGCCGTGGCGGACACTGTGTACCGAGCACTGCGCACGGAGCGTCGGGACCAGGCT
  GTGATGATCTCTGGGGAGAGCGGGGCAGGCAAGACCGAGGCCACCAAGAGGCTGCTGCAG
  TTCTATGCAGAGACCTGCCCAGCCCCCGAGCGCGGAGGTGCCGTGCGGGACCGGCTGCTA
  CAGAGCAACCCGGTGCTGGAGGCCTTTGGAAATGCCAAGACCCTCCGGAACGATAACTCC
  AGCAGGTTCGGGAAGTACATGGATGTGCAGTTTGACTTCAAGGGTGCCCCCGTGGGTGGC
  CACATCCTCAGTTACCTCCTGGAAAAGTCACGAGTGGTGCACCAGAATCATGGGGAGCGG
  AACTTCCACATCTTCTACCAGCTGCTGGAGGGGGGCGAGGAGGAGACTCTTCGCAGGCTG
  GGCTTGGAACGGAACCCCCAGAGCTACCTGTACCTGGTGAAGGGCCAGTGTGCCAAAGTC
  TCCTCCATCAACGACAAGAGTGACTGGAAGGTCGTCAGGAAGGCTCTGACAGTCATTGAT
  TTCACCGAGGATGAAGTGGAGGACCTGCTGAGCATCGTGGCCAGCGTCCTTCATTTGGGC
  AACATCCACTTTGCTGCCAACGAGGAGAGCAATGCCCAGGTCACCACCGAGAACCAGCTC
  AAGTATCTGACCAGGCTCCTCAGCGTGGAAGGCTCGACGCTGCGAGAAGCCCTGACACAC
  AGGAAGATCATCGCCAAGGGGGAGGAGCTCCTGAGCCCGCTGAACCTGGAGCAGGCCGCG
  TACGCACGAGACGCCCTCGCCAAGGCTGTGTACAGCCGCACTTTTACCTGGCTCGTCGGG
  AAGATCAACAGGTCGCTGGCCTCCAAGGACGTGGAGAGCCCCAGCTGGCGGAGCACCACG
  GTTCTCGGGCTCCTGGATATTTATGGCTTTGAAGTGTTTCAGCATAACAGCTTTGAGCAG
  TTCTGCATCAATTACTGCAACGAGAAGCTGCAGCAGCTCTTCATCGAGCTCACGCTCAAG
  TCGGAGCAGGAGGAGTACGAGGCAGAGGGCATCGCGTGGGAGCCCGTCCAGTATTTCAAC
  AACAAAATCATCTGTGATCTGGTGGAGGAGAAGTTTAAGGGCATCATCTCGATTTTGGAT
  GAGGAGTGTCTGCGCCCCGGGGAGGCCACAGACCTGACCTTCCTGGAGAAGCTGGAGGAT
  ACTGTCAAGCACCATCCACACTTCCTGACGCACAAGCTGGCTGACCAGCGGACCAGGAAA
  TCTCTGGGCCGAGGGGAATTCCGCCTTCTGCACTATGCGGGGGAGGTGACCTACAGCGTG
  ACCGGGTTTCTGGACAAAAACAATGACCTTCTCTTCCGGAACCTTAAGGAGACCATGTGT
  AGCTCAAAGAATCCCATTATGAGCCAGTGCTTTGACCGGAGCGAGCTCAGTGACAAGAAG
  CGGCCAGAGACGGTCGCCACCCAGTTCAAGATGAGCCTCCTGCAGCTGGTGGAGATCCTG
  CAGTCTAAGGAGCCCGCCTACGTCCGCTGCATCAAACCCAATGATGCCAAACAGCCCGGC
  CGCTTTGACGAGGTGCTGATCCGCCACCAGGTGAAGTACCTGGGGCTGTTGGAAAACCTG
  CGCGTGCGCAGAGCCGGCTTTGCCTATCGCCGCAAATACGAAGCTTTCCTGCAAAGGTAC
  AAGTCACTGTGCCCAGAGACGTGGCCCACGTGGGCAGGACGGCCGCAGGATGGGGTGGCT
  GTGCTGGTCCGACACCTGGGCTACAAGCCAGAAGAGTACAAGATGGGCAGGACCAAGATC
  TTCATCCGCTTCCCCAAGACCCTGTTTGCCACAGAGGATGCCCTGGAGGTCCGGCGGCAG
  AGCCTGGCCACAAAGATCCAAGCTGCCTGGAGGGGCTTTCACTGGCGGCAGAAATTCCTC
  CGGGTGAAGAGATCAGCCATCTGCATCCAGTCGTGGTGGCGTGGAACACTGGGCCGGAGG
  AAGGCAGCCAAGAGGAAGTGGGCGGCACAGACCATCCGGCGGCTCATCCGAGGCTTCGTC
  CTGCGCCACGCCCCCCGCTGCCCCGAGAACGCCTTCTTCCTGGACCATGTGCGCACCTCT
  TTTTTGCTAAACCTGAGGCGGCAGCTGCCCCAGAATGTCCTGGACACCTCGTGGCCCACG
  CCCCCACCTGCCCTGCGTGAGGCCTCAGAGCTTCTGCGGGAGTTGTGCATAAAGAACATG
  GTGTGGAAATACTGCCGGAGTATCAGCCCTGAGTGGAAGCAGCAGCTGCAGCAGAAGGCC
  GTGGCTAGTGAGATCTTCAAGGGCAAGAAGGATAATTACCCTCAGAGTGTACCCAGGCTC
  TTCATCAGCACTCGGCTTGGTACAGATGAGATCAGCCCCCGAGTGCTGCAGGCCTTGGGC
  TCTGAGCCCATTCAGTATGCGGTGCCTGTTGTGAAATACGACCGCAAGGGCTACAAGCCT
  CGCTCCCGGCAGCTGCTGCTCACGCCCAACGCCGTCGTCATCGTGGAGGACGCCAAAGTC
  AAGCAGAGGATTGATTACGCCAACCTGACCGGAATCTCTGTCAGCAGCCTGAGCGACAGT
  CTTTTTGTGCTTCATGTACAGCGTGCGGACAATAAGCAAAAGGGAGATGTGGTGCTGCAG
  AGTGACCACGTGATTGAGACGCTGACCAAGACAGCCCTCAGTGCCAACCGCGTGAACAGC
  ATCAACATCAACCAGGGCAGCATCACGTTTGCAGGGGGCCCCGGCAGGGATGGCACCATT
  GACTTCACACCCGGCTCGGAGCTGCTCATCACCAAGGCCAAGAACGGGCACCTGGCTGTG
  GTCGCCCCACGGCTGAATTCTCGGTGA
  
  Clone variation with respect to NM_033375.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033375 unedited
  AGGTTTACATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGCCGGCCG
  GGCAGAATGCGCTACCGGGCGTCGGCCCTGGGCAGTGACGGGGTTCGGGTGACCATGGAG
  AGTGCGCTCACCGCCCGTGACCGGGTGGGGGTGCAGGATTTCGTGCTGCTGGAGAACTTC
  ACCAGCGAGGCCGCCTTCATCGAGAACCTGCGGCGGCGATTTCGGGAGAATCTCATCTAC
  ACCTACATTGGCCCCGTCCTGGTCTCTGTCAATCCCTACCGGGACCTGCAGATCTACAGC
  CGGCAGCATATGGAGCGTTACCGTGGCGTCAGCTTCTATGAAGTGCCCCCTCACCTGTTT
  GCCGTGGCGGACACTGTGTACCGAGCACTGCGCACGGAGCGTCGGGACCAGGCTGTGATG
  ATCTCTGGGGAGAGCGGGGCAGGCAAGACCGAGGCCACCAAGAGGCTGCTGCAGTTCTAT
  GCAGAGACCTGCCCAGCCCCCGAGCGCGGAGGTGCCGTGCGGGACCGGCTGCTACAGAGC
  AACCCGGTGCTGGAGGCCTTTGGAAATGCCAAGACCCTCCGGAACGATAACTCCAGCANG
  TTCGGGAAGTACATGGATGTGCAGTTTGACTTCAAGGGTGCCCCCGTGGGTGGCCACATC
  CTCAGTTACCTCCTGGNAAAGTCACGAGTGGTGCACCAGAATCATGGGGAGCGGAACTTN
  CACATCTTCTACCANCTGCTGNAGGGGGGCGAGGNAGAGACTCTTTCGCAGCTGGGCTTG
  GAACGAACCCCCAGAGCTACCTGTACCTGGTGAAGGGCCAGTGTGCCAAGTCTNCTNCAT
  CAACGACCAGAGTGACTGGNAAGTCGTCAGGAAGGCTCTGACAGTCATTGATTTCACCGA
  GA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033375 unedited
  GCTCAACTTTGGTACGCTATACGNNGCTTTAGGGTCGAGTTTTTTTTTTTTTTTTTTAGA
  ACGGAGTCTCGCTCTGTTGCCAGGCTGAAGTGCAGTGGTGTACTCTTGGCTCACTGCAAC
  CTCCACTTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTAGA
  GGCGTGCACCACCATGCCCGGCTAATTTTGTATTTTTATTTTTTTCGGAGTTTCTCCATG
  TAGGTCAGGGGGGGCTCGAAATCCTGACCTCAGGTTATATGCCCGTCTCCATCTCCCAAA
  GTGCTGGGGTTACAGGCGTGAGCCACCATGCCCAGCCTAAAAGGACATTCTTAAGGCAGA
  AAGAAGGGGGCAGGCAAGGGTGGTCTCAGCCCCCAGATGGAAGTCAGAGTGGGCTGCAAA
  AGATGCAGATGGGCAGGCAGGGAGACAGGTAAACAGACAGAAAGACAAGGTGCCAAGGGA
  ATCAGGAGGAGAGGTGTCCTGGCCAGGGAAGAGGGCACCAGAGCCCAGCCCACACAACCT
  CTCGGCTACATTCCTTGCCCTGCTGGAGTCAGGGAAAACACATCCACTGTGTCCTTGGGT
  GGGAAATGGCTTTTTTAAAAAATAGTTTCCTATAAAGCATCAAAAAAACCTCAGAGAAAA
  CCTCAGCAAAAGTTCCCTTCTCTCAAATATTTGGCATCGGCAGTAGGGCTGGCATGGCTC
  GCTCTGGCCCTGGCTTTCCTATTGCTGTGGCCCGGCCTGGCCCAATCCGGGGGTAGCTCC
  TGGCCCCTGCTGCTCCCCTCAAAANAGGGATGGGCAAGGAGGTGGGAGATTGCAGGTGGG
  GCTTCGGGGTGTTCCCTGGGTCCCCTGTCTGGGAATTTCAATCTTTGGTAACAGGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033375
• Insert Size: 4400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_033375.3, NP_203693.2
• RefSeq Size: 4318 bp
• RefSeq ORF: 3087 bp
• Locus ID: 4641
• Cytogenetics: 17p13.3
• Domains: IQ, myosin_head
• Gene Summary: 'This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (c) has a shorter N terminus when compared to isoform a.