PMP22 (NM_153321) Human Untagged Clone

CAT#: SC100521

PMP22 (untagged)-Human peripheral myelin protein 22 (PMP22), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PMP22
• Synonyms: CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_153321 edited
  GAATTCGGCACGAGGCGCAGCCCCGCAGCGCAGCTTTGGCGGCGCCAGCAGCGGAGCCAA
  CGCACCCGAGTTTGTGTTTGAGGCCACCCTGAGGATCGGGACAGCTGTTCCTTTGGGCTG
  CAGAAACTCCGCTGAGCAGAACTTGCCGCCAGAATGCTCCTCCTGTTGCTGAGTATCATC
  GTCCTCCACGTCGCGGTGCTGGTGCTGCTGTTCGTCTCCACGATCGTCAGCCAATGGATC
  GTGGGCAATGGACACGCAACTGATCTCTGGCAGAACTGTAGCACCTCTTCCTCAGGAAAT
  GTCCACCACTGTTTCTCATCATCACCAAACGAATGGCTGCAGTCTGTCCAGGCCACCATG
  ATCCTGTCGATCATCTTCAGCATTCTGTCTCTGTTCCTGTTCTTCTGCCAACTCTTCACC
  CTCACCAAGGGGGGCAGGTTTTACATCACTGGAATCTTCCAAATTCTTGCTGGTCTGTGC
  GTGATGAGTGCTGCGGCCATCTACACGGTGAGGCACCCGGAGTGGCATCTCAACTCGGAT
  TACTCCTACGGTTTCGCCTACATCCTGGCCTGGGTGGCCTTCCCCCTGGCCCTTCTCAGC
  GGTGTCATCTATGTGATCTTGCGGAAACGCGAATGAGGCGCCCAGACGGTCTGTCTGAGG
  CTCTGAGCGTACATAGGGAAGGGAGGAAGGGAAACCAGAAAGCAGACAAAGAAAAAAGAG
  CTAGCCCAAAATCCCAAACTCAAACCAAACCAAACAGAAAGCAGTGGAGGTGGGGGTTGC
  TGTTGATTGAAGATGTATATAATATCTCCGGTTTATAAAACCTATTTATAACACTTTTTA
  CATATATGTACATAGTATTGTTTGCTTTTTATGTTGACCATCAGCCTCGTGTTGAGCCTT
  AAAGAAGTAGCTAAGGAACTTTACATCCTAACAGTATAATCCAGCTCAGTATTTTTGTTT
  TGTTTTTTGTTTGTTTGTTTTGTTTTACCCAGAAATAAGATAACTCCATCTCGCCCCTTC
  CCTTTCATCTGAAAGAAGATACCTCCCTCCCAGTCCACCTCATTTAGAAAACCAAAGTGT
  GGGTAGAAACCCCAAATGTCCAAAAGCCCTTTTCTGGTGGGTGACCCAGTGCATCCAACA
  GAAACAGCCGCTGCCCGAACCTGTGTGAAGCTTTACGCGCACACGGACAAAATGCCCAAA
  CTGGAGCCCTTGCAAAAACACGGCTTGTGGCATTGGCATACTTGCCCTTACAGGTGGAGT
  ATCTTCGTCACACATCTAAATGAGAAATCAGTGACAACAAGTCTTTGAAATGGTGCTATG
  GATTTACCATTCCTTATTATCACTAATCATCTAAACAACTCACTGGAAATCCAATTAACA
  ATTTTACAACATAAGATAGAATGGAGACCTGAATAATTCTGTGTAATATAAATGGTTTAT
  AACTGCTTTTGTACCTAGCTAGGCTGCTATTATTACTATAATGAGTAAATCATAAAGCCT
  TCATCACTCCCACATTTTTCTTACGGTCGGAGCATCAGAACAAGCGTCTAGACTCCTTGG
  GACCGTGAGTTCCTAGAGCTTGGCTGGGTCTAGGCTGTTCTGTGCCTCCAAGGACTGTCT
  GGCAATGACTTGTATTGGCCACCAACTGTAGATGTATATATGGTGCCCTTCTGATGCTAA
  GACTCCAGACCTTTTGTTTTTGCTTTGCATTTTCTGATTTTATACCAACTGTGTGGACTA
  AGATGCATTAAAATAAACATCAGAGTAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153321 unedited
  GGGGGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGCGCAGC
  CCCGCAGCGCAGCTTTGGCGGCGCCAGCAGCGGAGCCAACGCACCCGAGTTTGTGTTTGA
  GGCCACCCTGAGGATCGGGACAGCTGTTCCTTTGGGCTGCAGAAACTCCGCTGAGCAGAA
  CTTGCCGCCAGAATGCTCCTCCTGTTGCTGAGTATCATCGTCCTCCACGTCGCGGTGCTG
  GTGCTGCTGTTCGTCTCCACGATCGTCAGCCAATGGATCGTGGGCAATGGACACGCAACT
  GATCTCTGGCAGAACTGTAGCACCTCTTCCTCAGGAAATGTCCACCACTGTTTCTCATCA
  TCACCAAACGAATGGCTGCAGTCTGTCCAGGCCACCATGATCCTGTCGATCATCTTCAGC
  ATTCTGTCTCTGTTCCTGTTCTTCTGCCAACTCTTCACCCTCACCAAGGGGGGCAGGTTT
  TACATCACTGGAATCTTCCAAATTCTTGCTGGTCTGTGCGTGATGAGTGCTGCGGCCATC
  TACACGGTGAGGCACCCGGAGTGGCATCTCAACTCGGATTACTCCTACGGTTTCGCCTAC
  ATCCTGGCCTGNGTGGCCTTCCCCCTGGCCCTTCTCAGCGGTGTCATCTATGTGATCTTG
  CGGAAACGCGAATGAGGCGCCCAGACGGTCTGTCTGAGGCTCTGAGCGTCTANGGGAAAG
  GANGAAGGGAAACCACAAAGCAGACCAAGAAAAAAGAGCTAGCCCAAAATCCCAAACTCA
  AACCAAACCAAACAGAAAGCANNTGGAGGTGGGGGGTTGCTCGNTGATTGAAGATGTATA
  TAATATCTNCCGGTTTATAAAACCTATTTATAACACTTTNTACATATATGTACATAGNAA
  TGGNTTGCCTTTTTATTTTGACCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153321 unedited
  CTATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACTCTGATGT
  TTATTTTAATGCATCTTAGTCCACACAGGTGGCATAAAATCAGAAAATGCAAAGCAAAAA
  CAAAAGGTCTGGAGTCTTATCATCATAAGGGCACCATATATACATCTACAATTGGTGGCC
  AATACAAGTCATTGCCAGACAGTCCTTGGAGGCACAGAACAACCTATACCCATCCAAGCT
  CTAAGAACTCACGGTCCACCAGAGTCTAGACGCTTGTTCTGATGCTCCGACCGTAAGAAA
  AATGTGGCAGTGATGAAGGCTTTATGATTTACTCATTATACTAATAATAGCAGCCTAACT
  AGGTACAAAAGCAGTTATAAACCATTTATATTACACAGAATTATTCAAGTCTCCGTTCTA
  TCTTATGTTGAAAAATTGATAATTGGATTTCCAGTGAGTTGTTTAAATGACTACTGATGA
  TAATGAATGGAAAATCCGTAGCACCCTTTCAAAGACTTGTTGTCACTGATTTCTCATTTA
  AATGTGTGACGAAAATACTCCACCTGTAATGGCAAGTATGCCAATGCCACAAGCCGTGTT
  TTTTCAAAGGCTCCCTTTTGGGCATTATAGTCGTGTGCGCGTAAAGCTATCCACAAGTAT
  GGGCAGCGGCTGTTTCTGTTGGATCACAGTGTCACCCACCATACAAGGCTTGGATGGCAT
  TTGGGGTTTCTTCGCACACTTTGGTTTTCTAAATGAGGTGGACTGGGAGGGAGGTATCCT
  CTTTCACAGAAAAGGAAGGGCCAGATGGATTATCTTATTCTGGGTAAACAAACCGACACC
  CAAAACAACCGAAATCTGGGCTGGATTACTGTTAGAAGTAAAGTCCTACTACTTCTTAAG
  CTAACACCAGCTGATGGTCACTAAAAGCAACAAACTTTGTCCTTTGGAAAATGGTATAAA
  AG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153321
• Insert Size: 1750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_153321.1, NP_696996.1
• RefSeq Size: 1816 bp
• RefSeq ORF: 483 bp
• Locus ID: 5376
• Cytogenetics: 17p12
• Protein Families: Transmembrane
• Gene Summary: 'This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'
  Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-5 encode the same isoform (1).