ZADH1 (PTGR2) (NM_152444) Human Untagged Clone

CAT#: SC100899

PTGR2 (untagged)-Human prostaglandin reductase 2 (PTGR2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTGR2
• Synonyms: HEL-S-298; PGR2; ZADH1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_152444 edited
  ATGATTGTTCAAAGAGTGGTATTGAATTCTCGACCTGGAAAAAATGGTAATCCAGTGGCA
  GAGAATTTCCGAATGGAAGAAGTCTATTTACCAGATAATATTAATGAAGGACAAGTACAA
  GTTAGAACTCTTTATCTTTCTGTGGATCCTTACATGCGTTGTAGAATGAATGAAGACACT
  GGCACTGATTATATAACACCTTGGCAGCTATCTCAAGTCGTTGATGGTGGAGGTATTGGA
  ATTATAGAAGAAAGCAAACACACAAATTTGACTAAAGGCGATTTTGTGACTTCTTTCTAT
  TGGCCCTGGCAAACCAAGGTTATTCTGGATGGAAATAGCCTTGAAAAGGTAGACCCACAA
  CTTGTGGATGGACACCTTTCATATTTTCTTGGAGCTATAGGTATGCCTGGTTTGACTTCC
  TTGATTGGGATACAGGAAAAAGGTCATATAACTGCTGGATCTAATAAGACAATGGTTGTC
  AGTGGGGCCGCAGGTGCCTGTGGATCTGTGGCTGGGCAGATTGGCCATTTCTTAGGTTGT
  TCCAGAGTGGTGGGAATTTGTGGAACACATGAGAAATGCATCCTCTTGACCTCAGAACTG
  GGCTTTGATGCTGCAATTAATTATAAAAAAGACAATGTGGCAGAACAGCTCCGTGAATCA
  TGCCCAGCTGGAGTGGATGTTTATTTTGACAATGTTGGTGGTAACATCAGTGATACAGTG
  ATAAGTCAGATGAATGAGAACAGCCACATCATCCTGTGTGGTCAAATTTCTCAGTACAAC
  AAAGATGTGCCTTATCCTCCCCCGCTATCCCCTGCTATAGAGGCAATCCAGAAAGAAAGA
  AACATCACAAGGGAAAGATTTCTGGTATTAAATTATAAAGACAAATTTGAGCCTGGCATT
  CTACAGCTGAGTCAGTGGTTTAAAGAAGGAAAGCTAAAGATTAAAGAGACGGTAATAAAT
  GGGTTGGAAAACATGGGAGCTGCATTCCAGTCCATGATGACAGGAGGTAACATTGGAAAG
  CAGATAGTTTGCATTTCAGAAGAAATCTCTTTGTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152444 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCTGGGGGCGAGCTGGGG
  TCGTGCAGTACAGCCTCTTTCCGGCAAATCACGCGAGATTTCGTTCACCCGGGCTCCACA
  CGGAGTATTTTATACAGAAATCTTGTGAAACCACTGCCCAACCAGAGCAATGATTGTTCA
  AAGAGTGGTATTGAATTCTCGACCTGGAAAAAATGGTAATCCAGTGGCAGAGAATTTCCG
  AATGGAAGAAGTCTATTTACCAGATAATATTAATGAAGGACAAGTACAAGTTAGAACTCT
  TTATCTTTCTGTGGATCCTTACATGCGTTGTAGAATGAATGAAGACACTGGCACTGATTA
  TATAACACCTTGGCAGCTATCTCAAGTCGTTGATGGTGGAGGTATTGGAATTATAGAAGA
  AAGCAAACACACAAATTTGACTAAAGGCGATTTTGTGACTTCTTTCTATTGGCCCTGGCA
  AACCAAGGTTATTCTGGATGGAAATAGCCTTGAAAAGGTAGACCCACAACTTGTGGATGG
  ACACCTTTCATATTTTCTTGGAGCTATAGGTATGCCTGGTTTGACTTCCTTGATTGNGAT
  ACAGGANAAAGGTCATATAACTGCTGGATCTAATAAGAACATGGTTGTCAGTGGGGCCGC
  ANGTGCCTGTGGATCTGTGGGCTGGCAGATTGGCCATTTCTTAANGTTGTCCAGAGTGGT
  GGGAATTTGTGGACACATGAGAAATGCATCCTCCTGACCTCAGAACTGGGCTTTGATGCT
  GCATTAATTATAAAAAAGACATTGTGCCAGACAGCTCCCGTGATCATGCCCAGCTGGAGT
  GATGTTTATTTTGACATGGTTGTTGGTACATCAGTGATACAGTGATAGTCAGAGAATGAG
  ACCAGCCCATCTCCTGTGGGGTCAATTTTCAGTCACCAAGATGGCCTTATCTTCCCCGTT
  CCCTGTATAGAGCAATCAGAAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152444 unedited
  TCCCGTGGAGCCTATGGGCGATGGTCAACTTCCCAGGNCCAGAAAAGCACTGGGGNAGGG
  TACACAGGGCTGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTA
  GAGTCGAGTTTTTTTTTTTTTTTTTTCAAAAACAATAATCTTCAGTTTTACTGTTCTGCG
  AGGGTTGAGTACAATTAATAAAACAAACTTTTGAGGTACATCAGTAGTTCCTGAACATTC
  ATGTTTACAAACATTTGTTAATTTGCCCAGTCCTGTCATTTTCTGAAACTGTCTTTGTTG
  TCAATCTGTTTTTGTTTTTTGAGATGGAATTTCACTCTTATCGCCCAGGCTGGAGTGCAA
  TGGTGCAAGCTCAGCTCACGGCAACCTCCCCCTCCCAGGTTCAAATGATTCTCCAGCCTC
  AGCCTCCTGAGTAGCTGGGATTACAGGCGTGTGCCACCACGCCCAGCTAATTTTTGTATT
  TTAGAAGATGGGGGGGTTTCACCGNGTNGGCCAGGCTGGTCTCGAACTCCTGACCTCAAG
  TGATCTGCGCGCCTCTGCCTCCCAAAGTGCTAGGATTACAGGCTTGAGACATCAGGCCCG
  GCTGTCAATCTTTTTAATCACCTACAAGTGATGTTTACATCTGTTTGCCCTCTCAATCTT
  TACAACTTGACAGTATGTGCCTGCTAACCTAAAATAAACATATGCTTTTCTCAATATATA
  TGGAGTTTTTAGGCTATACAGTAAATTATTTGGCAAATACAAAGAGATGATCCTCTGGAG
  TAAATCTTGTCAACTTAACCAACCTAAGTTATTTATCTTTCCCATACTAAATCCAACCCA
  AAACCGCTGGTCTTCTATCCCAAAACTGTTACACAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152444
• ORF Size: 1056 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_152444.1, NP_689657.1
• RefSeq Size: 2538
• RefSeq ORF: 1056
• Locus ID: 145482
• Domains: ADH_zinc_N
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.