INSIG2 (NM_016133) Human Untagged Clone

CAT#: SC101330

INSIG2 (untagged)-Human insulin induced gene 2 (INSIG2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: INSIG2
• Synonyms: INSIG-2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101330 sequence for NM_016133 edited (data generated by NextGen Sequencing)
  ATGGCAGAAGGAGAGACAGAGTCACCTGGGCCCAAAAAGTGTGGCCCATATATTTCATCT
  GTCACTAGCCAGAGTGTGAACTTGATGATTCGAGGAGTAGTGCTATTTTTTATTGGAGTA
  TTTCTTGCATTAGTGTTAAATTTACTTCAGATTCAGAGAAATGTGACGCTCTTTCCACCT
  GATGTGATTGCAAGCATCTTTTCTTCTGCATGGTGGGTACCCCCATGCTGTGGCACGGCT
  TCAGCTGTGATTGGGTTATTATACCCCTGCATTGACAGACATCTAGGAGAACCACATAAA
  TTTAAAAGAGAGTGGTCCAGTGTAATGCGGTGTGTAGCAGTCTTTGTTGGTATAAATCAT
  GCCAGTGCTAAAGTGGATTTCGATAACAACATACAGTTGTCTCTCACACTGGCTGCACTA
  TCCATTGGACTGTGGTGGACTTTTGATAGATCTAGAAGTGGTTTTGGCCTTGGAGTAGGA
  ATTGCCTTCTTGGCAACTGTGGTCACTCAACTGCTAGTATATAATGGTGTTTACCAATAT
  ACATCTCCAGATTTCCTCTATGTTCGTTCTTGGTTACCATGTATATTTTTTGCTGGAGGC
  ATAACAATGGGAAACATTGGTCGACAACTGGCAATGTACGAATGTAAAGTTATCGCAGAA
  AAATCTCATCAGGAATGA
  
  Clone variation with respect to NM_016133.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016133 unedited
  TCGGACTTTGTAATAGACTCCTATAGGCGGCCGGATTCGCAGGGGGCCTGGGTCCCAGAA
  GTGGCGGAGGGCGGGGGAATTCTTGGTAGGTCCTACTTTAGGACAAGAATGTTGGTACCG
  TTGAAGCCGTCAGTTCTTTGATTCACAGACAGTTGAGCCTTTTCAGCTGGGAAGCCTTTC
  CATTTTTTTTTTTTTAACGGCTTTCTGAACCTATGAAACCATGGCAGAAGGAGAGACAGA
  GTCACCTGGGCCCAAAAAGTGTGGCCCATATATTTCATCTGTCACTAGCCAGAGTGTGAA
  CTTGATGATTCGAGGAGTAGTGCTATTTTTTATTGGAGTATTTCTTGCATTAGTGTTAAA
  TTTACTTCAGATTCAGAGAAATGTGACGCTCTTTCCACCTGATGTGATTGCAAGCATCTT
  TTCTTCTGCATGGTGGGTACCCCCATGCTGTGGCACGGCTTCAGCTGTGATTGGGTTATT
  ATACCCCTGCATTGACAGACATCTAGGAGAACCACATAAATTTAAAAGAGAGTGGTCCAG
  TGTAATGCGGTGTGTAGCAGTCTTTGTTGGTATAAATCATGCCAGTGCTAAAGTGGATTT
  CGATAACAACATACAGTTGTCTCTCACACTGGCTGCACTATCCATTGGACTGTGGTGGAC
  TTTTGATAGATCTAGAAGTGGGTTTTGCCTTGGAGTANGAATTGCCTTCTTGGCAACTGT
  GGTCACTCAACTGCTAGTATATAATGGTGGTTTACCAATATACATCTCCAGATTTCCTCT
  ATGTTCGTTCTTGGTTACCCTGTATATTTTTTTGCTGAAGCATAACCATGGGAAAACTTG
  GTCGACAACTGGCATGTTCCAATGTAAAGTTTCCCAAAAAAATCTCATCGGGATGAAGAA
  GGCAAAAATATTTTTTGTTCCAAAAAACCGGTGAAAAGGGTGTGAAATGGTTAATATCCC
  CCCAAACTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016133
• ORF Size: 678 bp
• Insert Size: 3500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016133.2, NP_057217.2
• RefSeq Size: 2592
• RefSeq ORF: 678
• Locus ID: 51141
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) and variant 2 both encode the same isoform (a).