IL28 Receptor alpha (IFNLR1) (AK097877) Human Untagged Clone

CAT#: SC101372

(untagged)-Human cDNA FLJ40558 fis, clone THYMU2002756

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNLR1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101372 sequence for AK097877 edited (data generated by NextGen Sequencing)
  ATGTCAGTGTTTCTTACAGCTCAAATTTGTATAGTTGTTTTAAAATGCGGTCTCTTTCTT
  CTTCCCCTGGTACTTTTTTCTTTCTGTCTACTGAAGTTAGTTCTTATACATGGTCTTATA
  TTTTGGCTGTCTTTTTTTCCCTAGGAACATTCATACAGGTTGAGTGTTCCTTATCTGAAA
  TGCTTGGGACTGGAAGTGTTTTTGATTTTGGAGTTTGGAATACTTTTTTTTTTTGGAGAT
  AGTGTTTTACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTTGGCTCGCTGCAAC
  CTCCGCCTCCCGGGTACAAGCGATTCTCCTGTTTCAGCCTCCCAAGTAGCTCGGATTACA
  GGCATGCGCCACCACGCCTGGCTAATTTTTTTGTATTTAGTAGAGATGGGTTTTCACCAT
  GTTAGCCAGGCTGGTTGTGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAA
  AATGCCGGGATTACAGGTGGGCACCACCATGCCCAGCCGGATTTTGGAATATTTTCATAA
  
  Clone variation with respect to AK097877.1
  143 g=>a;180 g=>a;213 t=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK097877 unedited
  TTCAAATATTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCATGCC
  TGGATAAATAAAATTGGTAGGAATGTTTTCTTGCCATTATATTTAACGTTTCTTCTTTTT
  CCTTGACAAATCTTGATAAGTTTTTTTATATTAGTTTTATTTTCTAGAAAACGTCTTATG
  AATTTCTCCCATTTGCTCTAGCATGCTTATAGAAAATGTCAGTGTTTCTTACAGCTCAAA
  TTTGTATAGTTGTTTTAAAATGCGGTCTCTTTCTTCTTCCCCTGGTACTTTTTTCTTTCT
  GTCTACTGAAGTTAGTTCTTATACATGGTCTTATATTTTGGCTGTCTTTTTTTCCCTAGG
  AACATTCATACAGGTTGAGTGTTCCTTATCTGAAATGCTTGGGACTGGAAGTGTTTTTGA
  TTTTGGAGTTTGGAATACTTTTTTTTTTTTGGAGATAGTGTTTTACTCTTGTTGCCCAGG
  CTGGAGTGCAATGGCGCAATCTTGGCTCGCTGCAACCTCCGCCTCCCGGGTACAAGCGAT
  TCTCCTGTTTCAGCCTCCCAAGTAGCTCGGATTACAGGCATGCGCCACCACGCCTGGCTA
  ATTTTTTTGTATTTAGTAGAGATGGGTTTTCACCATGTTAGCCAGGCTGGTTGTGAACTC
  CTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAATGCCGGGATTACAGGTGGGCAC
  CACCATGCCCAGCCGGATTTTGGAATATTTTCATAACACTTACTGGTGAGCACCCCTAAT
  CTGNAAATCCTAAATCTAAAATGCTTCCCAAATTGAAACTTTNTGAGCACCAGTATGATG
  CCCCCAGTGGAAAAATCCACACCCGACCTCATGTGATGAGTNCCAACTGTTGTATGCACA
  AAATTATTTAAAATATTGCATAAAATGACCTTTCAGCTATGATAGAAGGCGTCTATGAAT
  ATAAGNGAATTTCGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AK097877 unedited
  CTTGTACGCGGCCGCTTNCTAGGATCGAGTTTTTTTTTTTTTTTTTTCTTTTGAGACAGA
  TCCGGTTCTGTAGCCCAGGCTGAAGTGCGGTGGTGCGACCCCAGCCCACTGCAACCTCCA
  CCTCCCGGGTTCAAGCAATTCTCCTACCTCAGCCTCCAAAGTAGCTAGGATTACAGGTGT
  GCACCACCACCCCTGGCTAATTTTTTTTTTTTTAGTAGAGGCGAACTTTCACCATGTTGG
  CCAGGCTGGTCTCAAACCCCCGACCACAAGTGATCATCCCGACATGGCCTCCCAAAGTGC
  TGGGTTCACAGGTGTCAGCTACCGTGCCCAGCCTAAACCTATTATTTTCTATTAAAAATA
  ATGTTTTTCAACTCTATATGATCGCTTCCCAAGACGAAAGACCCGACCCCTAACCCAGAA
  AGACAAGCCACGAGCAGGAGCCCGGCGCAATTACTGAAACAAAAAGAACCACCCGGCCTG
  GGCGCGAACAAAAAAACGCACCTCATTCCCAAATTTATCAACACCAAACTCCCCGTGTAT
  TAAACACAACATTTAATAAAAATACCCATAATAAATTACCCATAAATAATTTCTTACTTG
  CTCACTTGTCAAACATTCACATTCTACGAGAACGCCCACAGAAAACTATCACTTATACAT
  GTGAACAACCCACATACATTAATATGAAAGAAGCTATTGTTAAATATACGAACCGAAATA
  CGTTTTATATTCTAATCGCACCAAACAAACATGCTACCCCACCGTACCCCCAAAAAGCTA
  TATGCACGATAACCATAAGAAACAATATACAAAATGCACAAAAAACCACACCGTCTACAT
  TACCCACACACTCGACAAGATGCACGATTCCCAAACCACCGACAAAGAAGAAACAACACT
  AATCAACAAAGAAAAAGCAGAACTAACATTTCTAAGCAACAAAGCCAACCAATATATAAC
  GCATTCACACACCGACAACGCGATCACACTGAAAACCTAACACAAGCACGAGTCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: AK097877
• ORF Size: 540 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK097877.1, BAC05191.1
• RefSeq Size: 1919
• RefSeq ORF: 540
• Locus ID: 163702
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]