RANTES (CCL5) (AK092450) Human Untagged Clone
CAT#: SC102926
(untagged)-Human cDNA FLJ35131 fis, clone PLACE6008824
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | CCL5 |
Synonyms | BDP|MSUDMV|PP2Ckappa|PP2Cm|PTMP|UG0882E07 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for AK092450, the custom clone sequence may differ by one or more nucleotides
AAGTACTTTATAGATTCAGAAGTAAATGCTGTCCTGTTCTCCATCAGCTGTTCGTTTGTTACAGATTTTG TATTTCTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTACAGTGGTGCGGTCT CGGCTCCCTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGAC TACAGGCGCGTGCCACCACCCCTGGCTAATTTTTGTATTTTTTTTTCTTTTTTTTTTGAGAAGGAGTCTC TCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTGCGCCTCCTGGGTTCAC GCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCGTCCGCCACCGTGCCCGGCTAATTTT TTTGTATTTTTAGTAGAGATGGGGTTTTGCCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTG ATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCAGATCTTTG TATGTCTTAAGTGTTTCAAAGTTATAAGCATTTTTCTGGGGGGATGTCCATTTTGGAGGGATCCATTTTG ATCCTTTGTACTCTATAATGTGAACTTTCCCCTGTTCCAACACTTAAAAGAGAATTATTAGCACATAATC TAAAAGATGGAATTTTTTTTTTTTCTTGAGACAGAGTCTCGCTCTGTCGCTAGGCTGGAGTGCAGTGGCG CGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTTAAGCGATTCTCCTGCCTCAGCCTCTGGAGTAGC TGGGACTACTCGTGCATGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCAT GTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACCTGCCTCGGCCTCCCAAATTGCTGGGATT ACAGCACTGTGCCCTCCTAGGAAATTATTTTTTAAGTGAAATTTTATTTTTATTTTTTTTAGGATTTTGG TAGAGAATGAGTAGGCCTACTCATCAATATCAAACAGGACATTTAGTTTCTTTCCTTAGAACAGACATAA ATTTAATTTCATGGTAATATGATAATAAGAAAATGCTTCTATTTTTCTTTAGCACCTCCATGGTTCTCAT ATACCCATGTCTGTAAAAAGTGACATGAGAATTTTGTTGGGTTACATTTTATTGTATTTATTAGATTCGC TTATATAGATGACTTAGGCAGAAATAAAGTCATGTCTTTAGAAGGTGAACAAGCCAACTTGTGATGGCCT GCCTTTTGCTTTTGGCAGTTGGGATGAGAACAATTGACTCTCCCATTGGTTGTTAGATAGTTGAAATGGT GCGTTGGTGGTCATACTTAGTGTTCTAGGCTGTGAAATCATGGAGTTCTTCCACTTCCAAGAATGACTCA TTTGCTGTTGGATTCTAGTACAGAATTTAGCAGCCTGATGTGTCCCCAAACTGATTTAATTTCTACTGAA GTGCCCTTGTGTACATTTGTTTTGTAATTTACCAAAGTACTACCTGAGTGTATAATGACTCCTGCAGTGA GTTAATGTAATTGCTGCTTTGACCATTGTTTTAAATCTGTGTACTAGAGTAACTGTGAGCAGAATGAAAT CACATTATCTCAGTGTTCAAAATATCATTCTAATAAAGTACATGCATTAAACAATTTT >OriGene 5' read for AK092450 unedited
GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTATAGGCATAG TGTAAATTACATTAATGTAGTAAAACATCAATTGTGGTTCGGTTTGTCTTTCATTTATGT GTAGTATAGAAATCACCTTTCTAATATGTGTTGCCAAACTATTTGCCACCATCTATTTGG TGAAATATTCATTGTCATTGTGATTTTCCACAAGTATAAGTTCTTAAGTACTTTATAGAT TCAGAAGTAAATGCTGTCCTGTTCTCCATCAGCTGTTCGTTTGTTACAGATTTTGTATTT CTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTACAGTGGT GCGGTCTCGGCTCCCTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTTCTGCCTCGGCC TCCTGAGTAGCTGGGACTGCAGGCGCGTGCCACCACCCCTGGCTAATTTTTGGATTTTTT TTTCTTTTTTTTTTTGAGAAGGAGTCTCTCTCTGTCACCCAGGCTGGAGTGCAGTGGCAC GATCTCGGCTCACTGCAAGCTGCGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTC CCGAGTAGCTGGAATTACAGGCGTCCGCCACCGTGCCCGGCTAATTTTTTTGTATTTTTA GTAGAGATGGGGTTTTGCCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGAT CCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCA GATCTTTGTATGTCTTAAGTGNTTCAAAGTTATAAGCATNTTTTCTGGGGGGGATGTCCA TTNNNTGGAGGGATCCCATTNTGATCCCTTTGNNACTCTATATGNGAAACTTTNCCCTGT TNNCACACTCANNAGAGAAT >OriGene 3' read for AK092450 unedited
TAAATCTATGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTGTTTA ATGCATGTACTTTATTAGAATGATATTTTGAACACTGGAGAAATGTGATTTCATTCTGCT CACAGTTACTCTAGTACACAGATTTAAAACAATGGTCAAAGCAGCAATTACATTAACTCA CTGCAGGAGTCATTATACACTCAGGTAGTACTTTGGTAAATTACAAAACAAATGTACACA AGGGCACTTCAGTAGAAATTAAATCAGTTTGGGGACACATCAGGCTGCTAAATTCTGTAC TAGAATCCAACAGCAAATGAGTCATTCTTGGAAGTGGAAGAACTCCATGATTTCACAGCC TAGAACACTAAGTATGACCACCAACGCACCATTTCAACTATCTAACAACCAATGGGAGAG TCAATTGTTCTCATCCCAACTGCCAAAAGCAAAAGGCAGGCCATCACAAGTTGGCTTGTT CACCTTCTAAAGACATGACTTTATTTCTGCCTAAGTCATCTATATAAGCGAATCTAATAA ATACAATAAAATGTAACCCAACAAAATTCTCATGTCACTTTTTACAGACATGGGTATATG AGAACCATGGAGGTGCTAAAGAAAAAAGAAGCATTTTCTTATTATCATATTACCATGAAA TTAAATTTATGTCTGGTCTAAGGAAAGAAACTAAATGTCCTGTTTGATATTGATGAGTAA GCCTACTCATTCTCTACCAAAATCTAAAAAAAATAAAAATAAAATTTCACTTTAAAAAAT AATTTNCCTAGAAGGCACAGTGCTGTTATTCCCACAATTTTGGGAGGCGAGGCAAGTGGG TCCACCCAGTCAAGAGATCGGGAACCTTCCTGCCCAATATGTGGAAACCCTGTCCTTCTA AAAATCCAAAAATTACCCGGCGGGTTGGCATGCCCCAATAT |
Restriction Sites | NotI-NotI |
ACCN | AK092450 |
Insert Size | 2000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | AK092450.1 |
RefSeq Size | 1738 bp |
RefSeq ORF | 1738 bp |
Locus ID | 6352 |
Cytogenetics | 17q12 |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway |
Gene Summary | 'This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]' |
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