ADO (NM_032804) Human Untagged Clone

CAT#: SC103692

ADO (untagged)-Human 2-aminoethanethiol (cysteamine) dioxygenase (ADO)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADO
• Synonyms: C10orf22
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC103692 sequence for NM_032804 edited (data generated by NextGen Sequencing)
  ATGCCCCGAGACAACATGGCCTCCTTGATCCAACGGATCGCCCGCCAGGCTTGCCTCACC
  TTCCGGGGCAGCGGGGGCGGCCGCGGCGCTTCCGATCGCGACGCGGCTTCTGGCCCGGAG
  GCGCCGATGCAGCCGGGCTTCCCCGAGAACCTGAGCAAGCTGAAGAGCCTCCTGACCCAG
  CTCCGCGCCGAGGACTTGAACATCGCCCCGCGCAAGGCCACACTGCAGCCGCTGCCGCCC
  AACCTGCCGCCAGTCACCTACATGCACATCTACGAGACGGACGGCTTCAGCCTGGGCGTG
  TTCCTGCTCAAGAGCGGCACGTCCATCCCGCTGCACGACCACCCGGGCATGCACGGCATG
  CTCAAGGTGCTGTACGGCACCGTGCGCATCAGCTGCATGGACAAGCTAGACGCGGGCGGC
  GGGCAACGGCCGCGGGCCTTGCCGCCCGAGCAGCAGTTCGAGCCGCCGCTGCAGCCCCGG
  GAGCGAGAAGCCGTGCGGCCGGGCGTGCTGCGTTCGCGGGCCGAGTACACCGAGGCCAGC
  GGCCCCTGCATCCTCACACCGCACCGGGACAACCTGCACCAGATCGACGCCGTGGAAGGG
  CCTGCCGCCTTCCTGGACATCCTGGCCCCGCCCTACGACCCGGACGATGGCCGGGACTGC
  CACTATTACCGGGTGCTGGAGCCGGTCAGGCCCAAGGAGGCCTCCAGCTCGGCCTGTGAC
  CTGCCTCGAGAGGTGTGGCTCCTGGAGACCCCACAGGCCGATGACTTCTGGTGCGAGGGA
  GAACCCTATCCAGGTCCCAAGGTCTTCCCTTGA
  
  Clone variation with respect to NM_032804.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032804 unedited
  CGCGTGCGCGCTCAGAGGGGGCTCAAGGCGAGCGCGCCGGGCAGTTGCGGGCGCGTGGCT
  GCTGAGGTTGGCGGCGGTGCCGCGCGCCCGACGGGCCGGTGGTTGCGGGGCCTCCCGCCT
  CGACCCGGGCTGGGGGCAGCCGTGGCGGCCGCCGGGGACCGCAAGGGGCGGAGGAAAGGA
  GGGGGCCGGTCCCGGCACGCAGAGGAGCAGCCGACCATGCCCCGAGACAACATGGCCTCC
  TTGATCCAACGGATCGCCCGCCAGGCTTGCCTCACCTTCCGGGGCAGCGGGGGCGGCCGC
  GGCGCTTCCGATCGCGACGCGGCTTCTGGCCCGGAGGCGCCGATGCAGCCGGGCTTCCCC
  GAGAACCTGAGCAAGCTGAAGAGCCTCCTGACCCAGCTCCGCGCCGAGGACTTGAACATC
  GCCCCGCGCAAGGCCACACTGCAGCCGCTGCCGCCCAACCTGCCGCCAGTCACCTACATG
  CACATCTACGAGACGGACGGCTTCAGCCTGGGCGTGTTCCTGCTCAAGAGCGGCACGTNC
  ATCCCGCTGCACGACCACCCGGGCATGCACGGCATGCTCAAGGTGCTGTACGGCACCGTG
  CGCATCAGCTGCATGGACAAGCTAGACGCGGGCGGCGGNCAACGGCCGCGGGCCTTGCCG
  NCCGAGCAGCAGTTCGAGCCGCCGCTGCAGCCCCGGGAGCGAAAACGGTGGCGCCNGGCG
  TGCTGCGTTCGCGGGCCGAGTACACCGAGGCCANNGGCCCCTGCTNCTCACACCGNACCG
  GGACACCTGCACANATCACACCCNGGGGAAAGCCCTGCGGCTTCCTGGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032804 unedited
  CTATGGAACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTGAGGCAAT
  TATTGCATTTATTATTCACCATAAAAGTGATTAATATCATTGTGCTCATTAGTCTTTCCA
  AGGGGAAGATAACTTTTATCCCACAGTTGTTATTAAAACATTATCTATATTGGACGGAGT
  ATATAGAAACACAATAGCAACACACCAAGTCAGTCACGACTAACAGTTTATGCACACAGG
  TGCAAGATAGTTTCTGCACCACATTTTGTCTTTGTAATAAGCATATTCTTTCCTCAGTGG
  CTCACTAAAACAAGTTATATTTTGTCTTCACCACTAATTTACTCAGAATTTATTAGTGAA
  CCAAAAGTTTCACTGTTCTTATTGAACTAAATCTGAGATATCATATTGCTGTTTTGGCCT
  GCAACAATTTCAGTTACTCTTTTGAAAAGCACCTTAGGTTTTTTCTTCCAAATTGCTCGT
  AATTGAAAACTTTAAAACTTCTTTTTTTCATAATGAAGTCATAATTCTTCCTTTATTACT
  ATCCTACAGCCAGGATGAGTTTTCGTAGCTTTAATGTACTAAGTTGTATTATAACACATA
  CATTGCTATTAATAATCTTGGTAAGCTAATCAACTTTTTGCTACAATATAATCCAAAAAA
  GTATGTGATTGATAACCACATTCATTACTGTGCTATGGAAAAAAAAACAAGATCTTTTAT
  TTTGTGAAGTTTTCTAAGAAAATCATTTGCATATCTAAGAATTTATTTTCAAACTAAGTG
  GCATGAAGAACTGCCTCAAACTGCCCCCAAAGGGCATTTTAAACTACCCCAAAATGTGGA
  AGCTACCATAAAACACATTTAGCCACAATGGCGGGAAAAACTTGGTACATGGCCCGTGGT
  CGGGTTTATAAAAAAGTGGCTGGCCCGGGGGAAAACCTTTTGGGTTTGGTTTGGGGTAAA
  TTAAAAACACTCACAGTGTTTGCGTGTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032804
• ORF Size: 813 bp
• Insert Size: 4000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_032804.5, NP_116193.2
• RefSeq Size: 3739
• RefSeq ORF: 813
• Locus ID: 84890
• Protein Pathways: Metabolic pathways, Taurine and hypotaurine metabolism
• Gene Summary: Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]). [supplied by OMIM, Mar 2008]