SETD2 (AK026837) Human Untagged Clone

CAT#: SC104183

(untagged)-Human cDNA: FLJ23184 fis, clone LNG11527, highly similar to AF049103 Human Huntingtin interacting protein mRNA

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SETD2
• Synonyms: HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|SET2|p231HBP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK026837, the custom clone sequence may differ by one or more nucleotides
  
  
  ACAGATATGATACACCAACTTCTAAAAAGAAAGTACGAATTAAAGACCGCAATAAACTTTCTACAGAGGA
  ACGCCGGAAGTTGTTTGAGCAAGAGGTGGCTCAACGGGAGGCTCAGAAACAACAGCAACAGATGCAGAAC
  CTGGGAATGACATCACCACTGCCCTATGACTCTCTTGGTTATAATGCCCCGCATCATCCCTTTGCTGGTT
  ACCCACCAGGTTATCCCATGCAGGCCTATGTGGATCCCAGCAACCCTAATGCTGGAAAGGTGCTCCTGCC
  CACACCCAGCATGGACCCAGTGTGTTCTCCTGCTCCTTATGATCATGCTCAGCCCTTGGTGGGACATTCT
  ACAGAACCCCTTTCTGCCCCTCCACCAGTACCAGTGGTGCCACATGTGGCAGCTCCTGTGGAAGTTTCCA
  GTTCCCAGTATGTGGCCCAGAGTGATGGTGTAGTACACCAAGACTCCAGCGTTGCTGTCTTGCCAGTGCC
  GGCCCCCGGCCCAGTTCAGGGACAGAATTATAGTGTTTGGGATTCAAACCAACAGTCTGTCAGTGTACAG
  CAGCAGTACTCTCCTGCACAGTCTCAAGCAACCATATATTATCAAGGACAGACATGTCCAACAGTCTATG
  GTGTGACATCACCTTATTCACAGACAACTCCACCAATTGTACAGAGTTATGCCCAGCCAAGTCTTCAGTA
  TATCCAGGGGCAACAGATTTTCACAGCTCATCCACAAGGAGTGGTGGTACAGCCAGCCGCAGCAGTGACT
  ACAATAGTTGCACCAGGGCAGCCTCAGCCCTTGCAGCCATCTGAAATGGTTGTGACAAATAATCTCTTGG
  ATCTGCCGCCCCCCTCTCCTCCCAAACCAAAAACCATTGTCTTACCTCCCAACTGGAAGACAGCTCGAGA
  TCCAGAAGGGAAGATTTATTACTACCATGTGATCACAAGGCAGACTCAGTGGGATCCTCCTACTTGGGAA
  AGCCCAGGAGATGATGCCAGCCTTGAGCATGAAGCTGAGATGGACCTGGGAACTCCAACATATGATGAAA
  ACCCCATGAAGGCCTCGAAAAAGCCCAAGACAGCAGAAGCAGACACCTCCAGTGAACTAGCAAAGAAAAG
  CAAAGAAGTATTCAGAAAAGAGATGTCCCAGTTCATCGTCCAGTGCCTGAACCCTTACCGGAAACCTGAC
  TGCAAAGTGGGAAGAATTACCACAACTGAAGACTTTAAACATCTGGCTCGCAAGCTGACTCACGGTGTTA
  TGAATAAGGAGCTGAAGTACTGTAAGAATCCTGAGGACCTGGAGTGCAATGAGAATGTGAAACACAAAAC
  CAAGGAGTACATTAAGAAGTACATGCAGAAGTTTGGGGCTGTTTACAAACCCAAAGAGGACGCTGAATTA
  GAGTGACTGTTGGGCCAGGGTGGGAGGATGGGTGGTCAGGTAAGACAGACTCTAGGGAGAGGAAATCCTG
  TGGGCCTTTCTGTCCCACCCCTGTCAGCACTGTGCTACTGATGATACATCACCCTGGGGAATTCAACCCT
  GCAGATGTCAACTGAAGGCCACAAAAATGAACTCCATCTACAAGTGATTACCTAGTTGTGAGCTGTTGGC
  ATGTGGTTAGAAGCCATCAGAGGTGCAAGGGCTTAGAAAAGACCCTGGCCAGACCTGACTCCACTCTTAA
  ACCTGGGTCTTCTCCTTGGCGGTGCTGTCAGCGCACAGACCCATGCGCATCCCCACCCACAACCCTTTAC
  CCTGATGATCTGTATTATATTTTAATGTATATGTGAATATATTGAAAATAATTTGTTTTTTCCTGGTTTT
  TGTTTGGTTTTCGTTTTGCTTTTAGCCTCTACATGCTAGGATCACAGGAAGACTTTGTAAGGACAGTTTA
  AGTTCTCCTGCAAGGTTTAATTTGTTATCATGTAAATATTCCAAAGCAGGCTGCCTTGTGGTTTTGGCCA
  GCCTTGTGCTATGTTGATAAGATTGATTTACTGCTTAAAATCACTTTACTTTATCCAATTTTTACTGAAC
  TTTTTATGTAAAAAAATAAAATCAATTAAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK026837 unedited
  CATAATATGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACCAGAGCAAACTCA
  AAATAAAGAGAAAAGGAAACGAAGAAGCTCCCTCTCACCACCCTCTTCTGCCTATGAGCG
  GGGAACAAAAAGGCCAGATGACAGATATGATACACCAACTTCTAAAAAGAAAGTACGAAT
  TAAAGACCGCAATAAACTTTCTACAGAGGAACGCCGGAAGTTGTTTGAGCAAGAGGTGGC
  TCAACGGGAGGCTCAGAAACAACAGCAACAGATGCAGAACCTGGGAATGACATCACCACT
  GCCCTATGACTCTCTTGGTTATAATGCCCCGCATCATCCCTTTGCTGGTTACCCACCAGG
  TTATCCCATGCAGGCCTATGTGGATCCCAGCAACCCTAATGCTGGAAAGGTGCTCCTGCC
  CACACCCAGCATGGACCCAGTGTGTTCTCCTGCTCCTTATGATCATGCTCAGCCCTTGGT
  GGGACATTCTACAGAACCCCTTTCTGCCCCTCCACCAGTACCAGTGGTGCCACATGTGGC
  AGCTCCTGTGGAAGTTTCCAGTTCCCAGTATGTGGCCCAGAGTGATGGTGTAGTACACCA
  AGACTCCAGCGTTGCTGTCTTGCCAGTGCCGGCCCCCGGCCCAGTTCAGGGACAGAATTA
  TAGTGTTTGGGATTAAACCAACAGTCTGTCAGTGTACAGCAGCAGTACTCTCCTGCACAG
  TCTCAAGCAACCATATATTATCAAGGACAGACATGTCCAACAGTCTATGGTGTGACATCA
  CCCTATTCACAGACAACTCCACCATTGTACCAGAGTATGTCCAGCCCAGTCTTCATATAT
  TCAGGGGCAACAGATTTTACAGCTCATCCACAGGAGTGTGGTACAGCAGCCCCACATTGA
  CTACATAGTTGACCAGGGCAGCCTAACCTTGAACCTCTGAATGGTGGGACAAAATCTTCT
  GAATTGCGCCCCTCTCCTCCAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AK026837 unedited
  GGAGACTCATGTACGTGGCCGCAATCNAGGATCGATTTTTTTTTTTTTTTTTTTTTTTTT
  TCTTTATTTGATTTTATTTTTTTACATAAAAAGTTCAGTAAAAATTGGATAAAGTAAAGT
  GATTTTAAGCAGTAAATCAATCTTATCAACATAGCACAAGGCTGGCCAAAACCACAAGGC
  AGCCTGCTTTGGAATATTTACATGATAACAAATTAAACCTTTTAGGAGAACTTAAACTGT
  CCTTACAAAGTCTTCCTGTGATCCTAGCATGTAGAGGCTAAAAGCAAAACGAAAACCAAA
  CAAAAACCAGGAAAAAACAAATTATTTTCAATATATTCACATATACATTAAAATATAATA
  CAGATCATCAGGGTAAAGGGTTGTGGGTGGGGATGCCCATGGGTCTGTGCGCTGACAGCA
  CCGCCCAGGAGAAGACCCAGGTTTAAAAATGGAGTCAGGTCTGGCCAGGGTCTTTTCTAA
  GCCCTTGCACCTCTGATGGGTTCTAACCACATGCCAACAGCTCACAACTAGGTAATCACT
  TGTAGATGGAGTTCATTTTTGTGGCCTTCAGTTGACATCTGCAGGGTTGAATTCCCCCAG
  GTGATGTATCATCAGTAGCACACTGCTGACAGGGGTGGGACAGAAAGGCCCACAGGATTT
  CCTCTCCCTAAAGGCTGTGTTACCTGAGCACCCATCCTCCCCCCCTGGGCCAACAGTCAC
  TCTAATTCAGAGGCCTCTTTGGGGTTGTAAACAGCCCCCAACTTCTGGATGTACTTCTTA
  AAGGACCCCCTTGGTTTTGGGGTCACAATCTCATTGGACTCCAGGGCCCCAAGGTTATTT
  ACAGAACTTCAGCTCCTTTATCATAACCCCCGGAGTCAACTTGGGACCCAAAAGTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: AK026837
• ORF Size: 2095 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK026837.1
• RefSeq Size: 2095
• RefSeq ORF: 2095
• Locus ID: 29072
• Domains: WW
• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation
• Gene Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]