MEGF10 (NM_032446) Human Untagged Clone

CAT#: SC104847

MEGF10 (untagged)-Human multiple EGF-like-domains 10 (MEGF10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MEGF10
• Synonyms: EMARDD
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032446, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTTATTTCTTTGAACTCATGCCTGAGCTTTATTTGTTTATTGTTATGCCACTGGATTGGGACAGCAT
  CACCTCTGAATCTTGAAGACCCTAATGTGTGTAGCCACTGGGAAAGCTACTCAGTGACTGTGCAAGAGTC
  ATACCCACATCCCTTTGATCAAATTTACTACACGAGCTGCACTGACATTCTAAACTGGTTTAAATGCACG
  CGGCACAGAGTCAGCTATCGGACAGCCTATCGACATGGGGAGAAGACTATGTATAGGCGCAAGTCTCAGT
  GTTGTCCTGGATTTTATGAAAGCGGGGAAATGTGTGTCCCCCACTGTGCTGATAAATGTGTCCATGGTCG
  CTGTATTGCTCCAAACACCTGTCAGTGTGAGCCTGGCTGGGGAGGGACCAACTGCTCCAGTGCCTGCGAT
  GGTGATCACTGGGGTCCCCACTGCACCAGCCGGTGCCAGTGCAAAAATGGGGCTCTGTGCAACCCCATCA
  CCGGGGCTTGCCACTGTGCTGCGGGCTTCCGGGGCTGGCGCTGCGAGGACCGCTGTGAGCAGGGCACCTA
  TGGTAACGACTGTCATCAGAGATGCCAGTGCCAGAATGGAGCCACCTGCGACCACGTCACGGGGGAATGC
  CGCTGCCCACCAGGATACACCGGAGCCTTCTGTGAGGATCTTTGTCCTCCTGGTAAACATGGTCCACAGT
  GTGAGCAGAGATGCCCTTGTCAAAATGGAGGAGTGTGTCATCACGTCACTGGAGAATGCTCTTGCCCTTC
  TGGCTGGATGGGCACAGTGTGTGGTCAGCCTTGCCCCGAGGGTCGCTTTGGAAAGAACTGTTCCCAAGAA
  TGCCAGTGCCATAATGGAGGGACGTGTGATGCTGCCACAGGCCAATGTCATTGCAGTCCAGGATACACAG
  GGGAACGGTGCCAGGATGAGTGTCCTGTTGGGACCTATGGCGTTCTCTGTGCTGAGACCTGCCAGTGTGT
  CAACGGAGGGAAGTGTTACCACGTGAGCGGCGCATGCCTCTGTGAAGCAGGCTTTGCTGGCGAGCGCTGC
  GAAGCACGCCTGTGTCCTGAGGGGCTCTACGGCATCAAATGTGACAAACGGTGTCCCTGCCACCTGGAAA
  ACACTCATAGCTGTCACCCCATGTCTGGAGAGTGTGCCTGCAAGCCGGGCTGGTCAGGACTCTACTGTAA
  TGAGACATGTTCTCCTGGATTCTACGGGGAAGCTTGCCAGCAGATCTGCAGCTGCCAAAATGGGGCAGAC
  TGTGACAGTGTGACTGGAAAGTGCACCTGTGCCCCAGGATTCAAAGGAATTGACTGCTCTACCCCATGCC
  CTCTGGGAACCTATGGGATAAACTGTTCCTCTCGCTGTGGCTGTAAAAATGATGCAGTCTGCTCTCCTGT
  GGACGGGTCTTGTACTTGCAAGGCAGGCTGGCACGGGGTGGACTGCTCCATCAGATGTCCCAGTGGCACA
  TGGGGCTTTGGCTGTAACTTAACATGCCAGTGCCTCAACGGGGGAGCCTGCAACACCCTGGACGGGACCT
  GCACGTGTGCACCTGGATGGCGCGGGGAGAAATGCGAACTTCCCTGCCAGGATGGCACGTACGGGCTGAA
  CTGTGCTGAGCGCTGCGACTGCAGCCACGCAGATGGCTGCCACCCTACCACGGGCCATTGCCGCTGCCTC
  CCCGGATGGTCAGGTGTCCACTGTGACAGCGTGTGTGCTGAGGGACGCTGGGGCCCCAACTGCTCCCTGC
  CCTGCTACTGTAAAAATGGGGCTTCATGCTCCCCTGATGATGGCATCTGCGAGTGTGCACCAGGCTTCCG
  AGGCACCACTTGTCAGAGGATCTGCTCCCCTGGTTTTTATGGGCATCGCTGCAGCCAGACATGCCCACAG
  TGCGTTCACAGCAGCGGGCCCTGCCACCACATCACCGGCCTGTGTGACTGCTTGCCTGGCTTCACAGGCG
  CCCTCTGCAATGAAGTGTGTCCCAGTGGCAGATTTGGGAAAAACTGTGCAGGAATTTGTACCTGCACCAA
  CAACGGAACCTGTAACCCCATTGACAGATCTTGTCAGTGTTACCCCGGTTGGATTGGCAGTGACTGCTCT
  CAACCATGTCCACCTGCCCACTGGGGCCCAAACTGCATCCACACGTGCAACTGCCATAATGGAGCTTTCT
  GCAGCGCCTACGATGGGGAATGTAAATGCACTCCTGGCTGGACAGGGCTCTACTGCACTCAGAGATGTCC
  TCTAGGGTTTTATGGAAAAGATTGTGCACTGATATGCCAATGTCAAAACGGAGCTGACTGCGACCACATT
  TCTGGGCAGTGTACTTGCCGCACTGGATTCATGGGACGGCACTGTGAGCAGAAGTGCCCTTCAGGAACAT
  ATGGCTATGGCTGTCGCCAGATATGTGATTGTCTGAACAACTCCACCTGCGACCACATCACTGGGACCTG
  TTACTGCAGCCCCGGATGGAAGGGAGCGAGATGTGATCAAGCTGGTGTTATCATAGTTGGAAATCTGAAC
  AGCTTAAGCCGAACCAGTACTGCTCTCCCTGCTGATTCCTACCAGATCGGGGCCATTGCAGGCATCATCA
  TTCTTGTCCTAGTTGTTCTCTTCCTACTGGCATTGTTCATTATTTATAGACACAAGCAGAAGGGAAAGGA
  ATCAAGCATGCCAGCAGTTACCTACACCCCTGCTATGAGGGTCGTCAATGCAGATTATACCATTTCAGGA
  ACCCTTCCTCACAGCAATGGTGGAAACGCTAATAGCCACTACTTCACCAATCCCAGTTACCACACGCTCA
  CCCAGTGTGCCACATCCCCTCACGTCAACAACAGGGACAGGATGACTGTCACGAAGTCAAAAAACAATCA
  ACTGTTTGTGAATCTTAAAAATGTGAACCCTGGGAAGAGAGGCCCTGTGGGGGACTGCACTGGGACATTG
  CCGGCTGACTGGAAACATGGCGGCTACCTCAACGAGCTCGGTGCTTTTGGACTTGACAGAAGCTATATGG
  GAAAATCCTTAAAAGACCTGGGAAAGAATTCTGAATATAATTCAAGTAACTGCTCCCTAAGCAGTTCTGA
  GAACCCATATGCCACTATTAAAGACCCACCTGTACTTATCCCGAAAAGCTCAGAGTGTGGTTATGTGGAG
  ATGAAATCGCCGGCACGAAGAGATTCCCCATATGCAGAGATCAATAACTCAACTTCAGCCAACAGGAATG
  TCTATGAAGTTGAACCTACAGTGAGTGTTGTCCAAGGAGTATTCAGCAATAATGGGCGTCTCTCCCAGGA
  TCCATATGACCTCCCAAAGAACAGTCACATCCCTTGTCATTATGACCTGCTGCCAGTCCGAGACAGTTCA
  TCCTCCCCTAAGCAAGAGGACAGTGGTGGTAGCAGCAGCAACAGCAGCAGCAGCAGTGAATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032446 unedited
  TTTTACCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGCCCGCCCCCACCCCCTCCAGCATCTCGGGCCAGACAGAGAAAACC
  TTGTTCAAGTTTGCAGCAAGTACTTTCCCGGTGCGCAAAACTGGGCGACTGGGAACGCGT
  TGAGACGTTCCTCTTTCCCGCTTCTCCACCTTTACGCCTGAAAGAAGACTCCCAAAGATT
  GCTTTCTTCTGGGACGCTGCTTGAACGCTAACCGCGTTGATTGGAACAGATTTTGTGTCT
  TGGCTGGCTTTGGGTGAAGACCGGGGAGAAAAGGTTGCGCTGCGATTCTCAAGATCTCTG
  GACCTGGGTTGTTCTTCAGAAAAAAATGGTTATTTCTTTGAACTCATGCCTGAGCTTTAT
  TTGTTTATTGTTATGCCACTGGATTGGGACAGCATCACCTCTGAATCTTGAAGACCCTAA
  TGTGTGTAGCCACTGGGAAAGCTACTCAGTGACTGTGCAAGAGTCATACCCACATCCCTT
  TGATCAAATTTACTACACGAGCTGCACTGACATTCTAAACTGGTTTAAATGCACGCGGCA
  CAGAGTCAGCTATCGGACAGCCTATCGACATGGGGAGAAGACTATGTATAGGCGCAAGTC
  TCAGTGTTGTCCTGGATTTTATGAAAGCGGNGAAATGTGTGTCCCCCACTGTGCTGATAA
  ATGTGTCCATGGTCGCTGTATTGCTCCAAACACCTGTCAGTGTGAGCCTGGCTGNNGAGG
  GACCAACTGCTCCAGTGCCTGCGATGGTGATCACTGGNGTCCCCACTGCACCAGCCGGTG
  CCAGTGCAAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032446 unedited
  CACCATTGGCCATGGCGATGGCAATTCCCATTTTCAGGANAGCACTGGGGCAGGGGTCAC
  AGGGCATGCCACCCGGGTTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGT
  CGAGTTTTTTTTTTTTTTTTTTCAAGCAAAAGATAAGTGGCAATAATACAAGGAATAACG
  AACATATAATATTTTTTCATTAACAATCCAAACACTACAAAACATAGAATATGCAATTTA
  AAAATGGAAATACAAATTAATGAAAAGTTGGGTACATGTCACATTAGCAATGCAAAAGAC
  CAGCTTAAGCATAGTTTCTCTAAATTGACAATTAATAAAAGGAAAGTTCCCTTTCTCAAA
  TATGCACAAAAATATTTCAGTCACTTCTAGGGAAGGATTAATCAAAATGTTCCACTAATT
  CTATATTACAGCATGTATTACTAATGGTTTACAGAACGTAAGCGTCATCTTGCATTTAAA
  ATTTACAACCTTTATCAATCATTACACACTCATTCCATCCAGTCTGTCAAAAATAAAATT
  ATTTCATTTCTATATTTATGAAATAACTATTGATATGTTATGAATCTCAAGTGGTGAATA
  TGTATGATGGAGCCAGTGATCAGAATAATGTCATAGATCTGAAGTTGGTTGAGAGTCAAA
  CAGAGAAAACCACCTCTGCCTGGCACATTTGTGTATTGACTTCTGCAATACTTCCTACTA
  TTTCTAAAATAATTCTAATTGTATATTTTCTCATTCTAAACAAAATCTAAGATTTTCGTA
  AATTTTCTGTCCACTTTTAGAGTATATTCAAAGTCTGTCCAGTCATACCGCCTGACAGAA
  TGTTTCCTNCTGCATTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032446
• ORF Size: 3423 bp
• Insert Size: 4600
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_032446.1, NP_115822.1
• RefSeq Size: 7522
• RefSeq ORF: 3423
• Locus ID: 84466
• Domains: EGF_Lam, EGF, EGF
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.