AAK1 (BC002695) Human Untagged Clone

CAT#: SC107754

AAK1 (untagged)-Homo sapiens, Similar to KIAA1048 protein, clone MGC:3535 IMAGE:3607681, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AAK1
• Synonyms: adaptor-associated kinase 1; AP2 associated kinase 1; DKFZp686F03202; DKFZp686K16132; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; KIAA1048; MGC138170; MGC164568; MGC164570
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107754 sequence for BC002695 edited (data generated by NextGen Sequencing)
  ATGAAGAAGTTTTTCGACTCCCGGCGAGAGCAGGGCGGCTCTGGCCTGGGCTCCGGCTCC
  AGCGGAGGAGGGGGCAGCACCTCGGGCCTGGGCAGTGGCTACATCGGAAGAGTCTTCGGC
  ATCGGGCGACAGCAGGTCACAGTGGACGAGGTGTTGGCGGAAGGTGGATTTGCTATTGTA
  TTTCTGGTGAGGACAAGCAATGGGATGAAATGTGCCTTGAAACGCATGTTTGTCAACAAT
  GAGCATGATCTCCAGGTGTGCAAGAGAGAAATCCAGATAATGAGGGATCTTTCAGGGCAC
  AAGAATATTGTGGGTTACATTGATTCTAGTATCAACAACGTGAGTAGCGGTGATGTATGG
  GAAGTGCTCATTCTGATGGACTTTTGTAGAGGTGGCCAGGTGGTAAACCTGATGAACCAG
  CGCCTGCAAACAGGCTTTACAGAGAATGAAGTGCTCCAGATATTTTGTGATACCTGTGAA
  GCTGTTGCCCGCCTGCATCAGTGCAAAACTCCTATTATCCACCGGGACCTGAAGGTTGAA
  AACATCCTCTTGCATGACCGAGGCCACTATGTCCTGTGTGACTTTGGAAGCGCCACCAAC
  AAATTCCAGAATCCACAAACTGAGGGAGTCAATGCAGTAGAAGATGAGATTAAGAAATAC
  ACAACGCTGTCCTATCGAGCACCAGAAATGGTCAACCTGTACAGTGGCAAAATCATCACT
  ACGAAGGCAGACATTTGGGCTCTTGGATGTTTGTTGTATAAATTATGCTACTTCACTTTG
  CCATTTGGGGAAAGTCAGGTGGCAATTTGTGATGGAAACTTCACAATTCCTGATAATTCT
  CGATATTCTCAAGACATGCACTGCCTAATTAGGTATATGTTGGAACCAGACCCTGACAAA
  AGGCCGGATATTTACCAGGTGTCCTACTTCTCATTTAAGCTACTCAAGAAAGAGTGCCCA
  ATTCCAAATGTACAGAACTCTCCCATTCCTGCAAAGCTTCCTGAACCAGTGAAAGCCAGT
  GAGGCAGCTGCAAAAAAGACCCAGCCAAAGGCCAGACTGACAGATCCCATTCCCACCACA
  GAGACTTCAATTGCACCCCGCCAGAGGCCTAAAGCTGGGCAGACTCAGCCGAACCCAGGA
  ATCCTTCCCATCCAGCCAGCGCTGACACCCCGGAAGAGGGCCACTGTTCAGCCCCCACCT
  CAGGCTGCAGGATCCAGCAATCAGCCTGGCCTTTTAGCCAGTGTTCCCCAACCAAAACCC
  CAAGCCCCMCCCAGCCAGCCTCTGCCGCAAACTCAGGCCAAGCAGCCACAGGCTCCTCCC
  ACTCCACAGCAGACGCCTTCTACTCAGGCCCAGGGTCTGCCCGCTCAGGCCCAGGCCACA
  CCCCAGCACCAGCAGCATACAATAAAACTTAGTATGAAACTTTAA
  
  Clone variation with respect to BC002695.2
  1269 a=>m
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC002695 unedited
  NGGGGAGGACTTTCGTGGAATTNTGTNAACCCGTATTTCACTGANAGGGNNCGGCCGCGN
  AATTCGGCACGAGGGAAACCATCGGTATTTTGCTTTGCTGCTCCCTATTCGCAAGATGAA
  GAAGTTTTTCGACTCCCGGCGAGAGCAGGGCGGCTCTGGCCTGGGCTCCGGCTCCAGCGG
  AGGAGGGGGCAGCACCTCGGGCCTGGGCAGTGGCTACATCGGAAGAGTCTTCGGCATCGG
  GCGACAGCAGGTCACAGTGGACGAGGTGTTGGCGGAAGGTGGATTTGCTATTGTATTTCT
  GGTGAGGACAAGCAATGGGATGAAATGTGCCTTGAAACGCATGTTTGTCAACAATGAGCA
  TGATCTCCAGGTGTGCAAGAGAGAAATCCAGATAATGAGGGATCTTTCAGGGCACAAGAA
  TATTGTGGGTTACATTGATTCTAGTATCAACAACGTGAGTAGCGGTGATGTATGGGAAGT
  GCTCATTCTGATGGACTTTTGTAGAGGTGGCCAGGTGGTAAACCTGATGAACCAGCGCCT
  GCAAACAGGCTTTACAGAGAATGAAGTGCTCCAGATATTTTGTGATACCTGTGAAGCTGT
  TGCCCGCCTGCATCAGTGCAAAACTCCTATTATCCACCGGGACCTGAAGGTTGAAAACAT
  CCTCTTGCATGACCGAGGCCACTATGTCCTGTGTGACTTTGGAAGCGCCACCAACAAATT
  CCAGAATCCACANAACTGAGGAGTCAATGCAGTAGAAGATGAGATTAAGAAATACACAAC
  GCTGTCCTATCGAGCACCAGAAATGGTCAACCTGTACAGTGGCAAAATCATCACTACGAA
  AGCAGACATTTGGGCTCTTGGAATNNNTTGTGTATAAAATATGCTACTTCACTTTGCCAT
  TTGGGGAAAGTCAGGTGGCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for BC002695 unedited
  GTATACTAGGACCGCGCCCAATCTANATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TAAAAGTTTCAAACAAATTTTTATTGTACCCCCCGGGGGCCGGGGGGGGGCCGGGGCCCG
  AACGGGCAAACCCGGGGCCCGAAAAAAAAGCCCCCCCCGGGGAGGGGGAAAACCCCGGGG
  CCCCTTGGCCCGATTTTGCGCCAAAAGCCGGCGGGGGGGGGCCTGGGGTTTTGGTTGGGA
  AACACCGGCAAAAAGGCCCGCCTGATTGCGGGACCCCGCCCCCCGGGGGGGGGGCCAAAC
  AGGGGCCCCCTTCCGGGGGGTCACCCCCGGCTGGAAGGAAAAGAACCCCGGGTTCCGCCG
  AATCCCCCCAACTTTAGCCCCCGGGGGGGGGGCAATTGAAACCCCCGGGGGGGGAAAGGG
  ATCCGGCAACCCGGCCTTTGGGGGGGTCTTTTTTGCCCCCGCCCCACGGGCTTTCACGGG
  TTAAAAAACCTTTGCAGGAAGGGGAAAATTCCGGCCCTTTGGAATTGGGCCCCCTTTCCT
  GAGTACCCTAAAAGAAAAATAGGACCCCCGGAAAAAACCCCGCCTTTTGGCAGGGGCGGG
  TTCCCACAAAAACCTAATTAAGCCGGGCATGTCTTGAAAAATACGAAAAATNCCCGGAAT
  TGGGAAATTTCCACACAAAAGGCCCCCTGACTTTCCCCAAAGGGAAAGGGGAAGTCCCTA
  ATTTATACAACAAACACCCAAAACCCCAAATGGCCGCCCTCCAAGGGAAGAATTTGCCCC
  GGCACGGGGTGACCATTTCGGGGCCCCAAAAGAAACCCCTTGGGTATTTCCAAACCC
  
• Restriction Sites: Please inquire
• ACCN: BC002695
• ORF Size: 1425 bp
• Insert Size: 1650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC002695.2, AAH02695.1
• RefSeq Size: 1513
• RefSeq ORF: 1425
• Locus ID: 22848
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]