BACH1 (NM_001186) Human Untagged Clone

CAT#: SC107917

BACH1 (untagged)-Human BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BACH1
• Synonyms: BACH-1; BTBD24
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107917 sequence for NM_001186 edited (data generated by NextGen Sequencing)
  ATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAATCTTCTGTGCATAGCACCAATGTT
  TTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTG
  GAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCAC
  TCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACATTACTCTTCCAGAAGAGGTGACA
  GTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAA
  GAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAA
  TCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACTCCACTGCAGACCAGCAAGAATGC
  CCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTG
  GACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAG
  ACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATGCAAAAGCCTCACCTCCTCTACAA
  GACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTG
  CCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGT
  ACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTGTTCAGCCAAATGAAAGGTCTGAA
  AATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGAC
  GAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCA
  ACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATTCTTCCATAGACCCTCATGGACTT
  TATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATG
  CAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACA
  TTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACTTGGGCACCAGGGAAGATAGTAGT
  GTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGC
  TTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTG
  GCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGTCTGAGTGTCCGTGGTTAGGTATC
  AGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAAC
  TGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAAC
  GATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCCCATATGCTTGTGTCATTAGCTTG
  GGAGATGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAA
  GAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGAT
  TTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAGAACAGCTGGATTGTATCCATGAT
  ATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGAC
  TGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGCAAAGTGAAAAGGAGAGCTTGTTG
  AAGGAAAGAGATCACATTTTGTCAACTCTGGGTGAGACAAAGCAGAACCTAACTGGACTT
  TGCCAGAAAGTTTGTAAAGAAGCAGCTCTGAGTCAAGAACAAATACAGATACTCGCCAAG
  TACTCAGCTGCAGATTGCCCACTTTCATTTTTAATTTCTGAAAAAGATAAAAGTACTCCT
  GATGGTGAACTGGCGTTACCATCAATTTTCAGTTTATCTGACCGGCCTCCAGCAGTGCTG
  CCTCCCTGTGCCAGAGGAAACAGTGAGCCTGGCTACGCGCGAGGGCAGGAGTCCCAGCAG
  ATGTCCACAGCCACCTCTGAGCAAGCTGGGCCTGCGGAACAGTGTCGTCAGAGTGGTGGG
  ATCTCAGATTTCTGTCAGCAGATGACTGATAAATGTACTACTGATGAGTAA
  
  Clone variation with respect to NM_001186.2
  1506 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001186 unedited
  GCGAATTCGGCACGAGGCCGCGCCGCGCCTCAGCTCTGGTTGATGATAATTAGAAGCATG
  CTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGG
  TTTTTGCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGC
  GGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGACAGCGGTTCCGCGCTC
  ACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTG
  ATGGAGAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAA
  TTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATGTGGATGAAGTGTGCA
  AATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAAT
  TTAAGTTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCAT
  CACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGAGGGATCTAGAAACTG
  ATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTGAACTCCGCA
  GGTATCAAGGAAATGCANAAGCCTCACCTCCTCTTACAGACAGTGCCAGTCAGACATATG
  AGTCCATGTGCTTAGAGAAGGATGCTGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001186 unedited
  TTTTTTCATTAAAACCATTTTTAAAAATTTTTATTTAACTGTCAACTTATACACCAACAT
  TTAACATTTTTTAGTTCAGGTCCATTGGGGTAAAAACATTAGGGAAAAAATGTAAATTAA
  ATCCTATGAACCTATGCTTTTAATGAACCATGGTCTCAGTAAAATATGGACACAAAGGTT
  TAGGGGTTTTATTGCATTGTTAAAAAATTATTTTATGAAAAATATAAAAAAATCAGGGTT
  TTTCTGCTTCTTTTATAACCAGTATGCCATCTTTAACCATTATGGTTTTAATTTTCATTC
  TACCCAACAAGTTTAAAAAAATAGTTTATTACATGCCTTAATAAAACATTTAAAATATTT
  ACAGATTCAAAATAAATGTTTTATAACTGAAAAAAGTTCACCTGAAAATCCACCGTACCA
  TTGCCATTTTTTTCCCAAGTTACTAATGTGACTGAGTGCCCACATGCAACCTGTATCGTC
  TACTGCATCTAACATACTTATTTCCTTATTAAAAATTAGTTAACCAGTAACCTATAGCAA
  ACTGTTAAAAAAAATTACAGATGGAAAACCAAGACTGTTTCCACTTTTGTTTTGAATATG
  ACAATTTAACGAATTATTTGCTATAGTTCCAAAATTTGAATAAAAAAAAAAATAAGGTAA
  TGTTATTTTACTGATTTCAACATACCAGCCTTAAAAAAAATCTTCAAACATTGAGAAGGC
  CATTTCTAAAAAAGGGAACAATGATCATGTGAATTTGCATTATACAAACTGGAAAACTTT
  TAAAATTCTGCATGAGGAAAAGGCCACCCTGAAACTCATAATCCCGCCATTTGGCTCCGA
  CACCATAAAAAAAATGGCCTTGAACCTTTTCTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001186
• Insert Size: 5200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001186.2, NP_001177.1
• RefSeq Size: 5642 bp
• RefSeq ORF: 2211 bp
• Locus ID: 571
• Cytogenetics: 21q21.3
• Domains: BTB, BRLZ
• Protein Families: Transcription Factors
• Gene Summary: 'This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.