RAD18 (NM_020165) Human Untagged Clone

CAT#: SC108413

RAD18 (untagged)-Human RAD18 homolog (S. cerevisiae) (RAD18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAD18
• Synonyms: RNF73
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108413 sequence for NM_020165 edited (data generated by NextGen Sequencing)
  ATGGACTCCCTGGCCGAGTCTCGGTGGCCTCCGGGCCTGGCAGTCATGAAGACAATAGAT
  GATTTGCTGCGGTGTGGAATTTGCTTCGAGTATTTCAACATTGCAATGATAATACCTCAG
  TGTTCACATAACTACTGCTCTCTCTGTATAAGAAAATTTCTGTCCTATAAAACTCAGTGT
  CCAACTTGCTGTGTGACTGTCACAGAGCCGGATCTGAAAAATAACCGCATATTAGATGAA
  CTGGTAAAAAGCTTGAATTTTGCACGGAATCATCTGCTGCAGTTTGCTTTAGAGTCACCA
  GCCAAATCTCCTGCTTCTTCCTCTTCAAAGAATCTTGCTGTCAAAGTATATACTCCTGTA
  GCCTCCAGACAGTCTTTAAAGCAGGGGAGCAGGTTAATGGATAATTTCTTGATCAGAGAA
  ATGAGTGGTTCTACATCAGAGTTGTTGATAAAAGAAAATAAAAGCAAATTCAGCCCTCAA
  AAAGAGGCGAGCCCTGCTGCAAAGACCAAAGAGACACGTTCTGTAGAAGAGATCGCTCCA
  GATCCCTCAGAGGCTAAGCGTCCTGAGCCACCCTCGACATCCACTTTGAAACAAGTTACT
  AAAGTGGATTGTCCTGTTTGCGGGGTTAACATTCCAGAAAGTCACATTAATAAGCATTTA
  GACAGCTGTTTATCACGCGAAGAGAAGAAGGAAAGCCTCAGAAGTTCTGTTCACAAAAGG
  AAGCCGCTGCCCAAAACTGTATATAATTTGCTCTCTGATCGTGATTTAAAGAAAAAGCTA
  AAAGAGCATGGATTATCTATTCAAGGAAATAAACAACAGCTCATTAAAAGGCACCAAGAA
  TTTGTACACATGTACAATGCCCAATGCGATGCTTTGCATCCTAAATCAGCTGCTGAAATA
  GTTCGAGAAATCGAAAATATAGAGAAGACTAGGATGCGTCTTGAAGCTAGTAAACTCAAT
  GAAAGTGTAATGGTTTTTACAAAGGACCAAACAGAAAAGGAAATAGATGAAATCCACAGT
  AAATATCGTAAAAAACATAAGAGTGAATTTCAGCTTCTGGTGGATCAGGCTAGAAAAGGA
  TACAAGAAAATTGCTGGAATGTCACAAAAAACAGTAACAATAACAAAAGAAGATGAATCT
  ACAGAAAAGCTATCTTCTGTATGCATGGGACAGGAAGATAATATGACCTCAGTAACAAAC
  CACTTTTCTCAATCAAAGCTGGACTCCCCAGAGGAATTGGAACCTGACAGAGAAGAGGAT
  TCTTCTAGCTGTATTGATATTCAAGAAGTTCTTTCTTCATCAGAATCAGATTCATGCAAT
  AGTTCCAGTTCAGACATCATAAGAGATCTTTTAGAAGAAGAGGAAGCCTGGGAAGCATCA
  CATAAAAACGATCTTCAAGACACAGAAATAAGTCCAAGACAGAATCGCCGCACAAGAGCC
  GCTGAAAGTGCTGAGATTGAACCAAGAAACAAGCGTAATAGGAATTAA
  
  Clone variation with respect to NM_020165.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020165 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGG
  CACGAGGGACCCCCAGCATCCTCGAGAGCGACCATGGACTCCCTGGCCGAGTCTCGGTGG
  CCTCCGGGCCTGGCAGTCATGAAGACAATAGATGATTTGCTGCGGTGTGGAATTTGCTTC
  GAGTATTTCAACATTGCAATGATAATACCTCAGTGTTCACATAACTACTGCTCTCTCTGT
  ATAAGAAAATTTCTGTCCTATAAAACTCAGTGTCCAACTTGCTGTGTGACTGTCACAGAG
  CCGGATCTGAAAAATAACCGCATATTAGATGAACTGGTAAAAAGCTTGAATTTTGCACGG
  AATCATCTGCTGCAGTTTGCTTTAGAGTCACCAGCCAAATCTCCTGCTTCTTCCTCTTCA
  AAGAATCTTGCTGTCAAAGTATATACTCCTGTAGCCTCCAGACAGTCTTTAAAGCAGGGG
  AGCAGGTTAATGGATAATTTCTTGATCAGAAAATGAGTGGTTCTACTCAGAGTTGTTGAT
  AAAGAAATAAAAGCAATTCACCCTCAAAAGAGCGAGCCCTGCTGAAAGACCAAGAGACAC
  GTTCTGAAAGAGATCGCTCAATCCTCAAGGCTAACGTCTGAGCCACCTCGACATCCTTGA
  ACAAGTACTAAGTGGATNNGTCTGTTGCGGGNTACATTCAAAAAGCCATTTATACATTAC
  CAGCTGNTATCACCGAAAGAAGAAGCCTAAAANTTTGTACAAAGAAGCCCTCCAAACTGT
  TTAATNGCTCTTGGACGGTTAAGAAACTAAAACTGGGTTTTCTTCAGAATACACGCTCTA
  AAGCCCAAATTTNCCCGCCAGGCAGGGAGGTTTCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020165 unedited
  TCTCGCTGTACGACCCACTCTTAGCACTAGATAAGTAGTCATGNAAACAAACAGTTTTCA
  TTTTGACATAATTTCTGACAACTCAGTGACATAAATATATCCATGTGAGCTCCTATTTTG
  TTTGACATGCTCACTTACCTCACATCAGTTCTGCCGATAGATTTGGTAAGTGGTGCTTTT
  AGTTTCCTTAATGCACCCCTCAGGATTTCATGCAAATGAAATTATTATGACAAATTTTTC
  TATAGCCATTTCTAACACAGGGAACTCATAAAGAAATCAAATGTCTGCACTTCACTGTGA
  AAACACTAAACTCTCAGCCATAATGAGACTCCACACATTATCAGAAACCCCAAGGCATAC
  CAAAAAGACAAGGTCAACGGAGACAGCCTCTGGAAGGGGAGGTCATACCTGCCGCAACCT
  GGCCAACCATAAATCTCTAGTTTTAACATTGCCGCATTTACTATCATCTCATTTGAAAGC
  TGATGTGCTTGGGCTGTTTGATAACCCCAGGCGTGGACTCGTGCTATGCTGTACTCGAAC
  GCCTCACCCGCCTCCGAACTCTTGAAACCCCGGCTTCTGCTCTAACTCTTACCATCTGGT
  TTCTTGACCCCCCTTTTCTATGACTCTTATCCACCCCCTACCTTTCCACGCCCCCGCCTC
  ACAACCCTCTCTCTTTCTGACCCCCCTTTTTCTTTCCTCACTCTCTCCTCCCCTCCCTCC
  CCCCTCGTACCTCTCTATCCCTGTCTTCCACCCTCCTCGCCTCCTCTGACCCATCCTCCT
  TTCTTTCATTATTAAGTCCTCTCTCACTCTATTTTCGTTAGCCTTCATTTCACTATCTCT
  ACGGCCCTCCTCCTCTCTAATTATTCCAACACCTTCCTCATCCTTTTCTATTTCTAAAAC
  CCGTCCTTCAATCACAATTCTCATCCCTCTTCTATATCCTTATCCCTCCGTTTCCCCCAC
  TCTTTACTCTCTCTTATCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_020165
• ORF Size: 1488 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020165.2, NP_064550.2
• RefSeq Size: 3053
• RefSeq ORF: 1488
• Locus ID: 56852
• Domains: RING, SAP, ZnF_Rad18
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]