PEG10 (NM_015068) Human Untagged Clone

CAT#: SC108513

PEG10 (untagged)-Human paternally expressed 10 (PEG10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEG10
• Synonyms: EDR; HB-1; Mar2; Mart2; MEF3L; RGAG3; RTL2; SIRH1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015068, the custom clone sequence may differ by one or more nucleotides
  
  
  CTCCTCGGTGCAACCTATATAAGGCTCACAGTCTGCGCTCCTGGTACACGCGCTTCAACTTCGGTTGGTG
  TGTGTCGAAGAAACCTGACTGCGCCCTGAGGAGAACAGCGGAGAAGGTCCACCGAGCCTGGCGAAAGGTC
  CGCTGAGCGGGCTGTCGTCCGGAGCCACTCCGGGCTGCGGAGCACCCAGTGGAGACCGCGCCTGGCTCAG
  GTGTGGGACCCCATCCTTCCTGTCTTCGCAGAGGAGTCCTCGCGTGAAATAAGCGGGTTTTGAAAACAAA
  AAAAAGAAGGAGTGGAAGAGGGGGCCAGGATCCAGGCCTCCATCCCCACAGAAGTGAAGCTACAGCTGGG
  AGGTCTCCTCCCACCCCAACCGTCACCCTGGGTCCCGACTGCCCACCTCCTCCTCCTCCCCCTCCCCCCA
  ACAACAACAACAACAACAACTCCAAGCACACCGGCCATAAGAGTGCGTGTGTCCCCAACATGACCGAACG
  AAGAAGGGACGAGCTCTCTGAAGAGATCAACAACTTAAGAGAGAAGGTCATGAAGCAGTCGGAGGAGAAC
  AACAACCTGCAGAGCCAGGTGCAGAAGCTCACAGAGGAGAACACCACCCTTCGAGAGCAAGTGGAACCCA
  CCCCTGAGGATGAGGATGATGACATCGAGCTCCGCGGTGCTGCAGCAGCTGCTGCCCCACCCCCTCCAAT
  AGAGGAAGAGTGCCCAGAAGACCTCCCAGAGAAGTTCGATGGCAACCCAGACATGCTGGCTCCTTTCATG
  GCCCAGTGCCAGATCTTCATGGAAAAGAGCACCAGGGATTTCTCAGTTGATCGTGTCCGTGTCTGCTTCG
  TGACAAGCATGATGACCGGCCGTGCTGCCCGTTGGGCCTCAGCAAAGCTGGAGCGCTCCCACTACCTGAT
  GCACAACTACCCAGCTTTCATGATGGAAATGAAGCATGTCTTTGAAGACCCTCAGAGGCGAGAGGTTGCC
  AAACGCAAGATCAGACGCCTGCGCCAAGGCATGGGGTCTGTCATCGACTACTCCAATGCTTTCCAGATGA
  TTGCCCAGGACCTGGATTGGAACGAGCCTGCGCTGATTGACCAGTACCACGAGGGCCTCAGCGACCACAT
  TCAGGAGGAGCTCTCCCACCTCGAGGTCGCCAAGTCGCTGTCTGCTCTGATTGGGCAGTGCATTCACATT
  GAGAGAAGGCTGGCCAGGGCTGCTGCAGCTCGCAAGCCACGCTCGCCACCCCGGGCGCTGGTGTTGCCTC
  ACATTGCAAGCCACCACCAGGTAGATCCAACCGAGCCGGTGGGAGGTGCCCGCATGCGCCTGACGCAGGA
  AGAAAAAGAAAGACGCAGAAAGCTGAACCTGTGCCTCTACTGTGGAACAGGAGGTCACTACGCTGACAAT
  TGTCCTGCCAAGGCCTCAAAGTCTTCGCCGGCGGGAAACTCCCCGGCCCCGCTGTAGAGGGACCTTCAGC
  GACCGGGCCAGAAATAATAAGGTCCCCACAAGATGATGCCTCATCTCCACACTTGCAAGTGATGCTCCAG
  ATTCATCTTCCGGGCAGACACACCCTGTTCGTCCGAGCCATGATCGATTCTGGTGCTTCTGGCAACTTCA
  TTGATCACGAATATGTTGCTCAAAATGGAATTCCTCTAAGAATCAAGGACTGGCCAATACTTGTGGAAGC
  AATTGATGGGCGCCCCATAGCATCGGGCCCAGTTGTCCACGAAACTCACGACCTGATAGTTGACCTGGGA
  GATCACCGAGAGGTGCTGTCATTTGATGTGACTCAGTCTCCATTCTTCCCTGTCGTCCTAGGGGTTCGCT
  GGCTGAGCACACATGATCCCAATATCACATGGAGCACTCGATCTATCGTCTTTGATTCTGAATACTGCCG
  CTACCACTGCCGGATGTATTCTCCAATACCACCATCGCTCCCACCACCAGCACCACAACCGCCACTCTAT
  TATCCAGTAGATGGATACAGAGTTTACCAACCAGTGAGGTATTACTATGTCCAGAATGTGTACACTCCAG
  TAGATGAGCACGTCTACCCAGATCACCGCCTGGTTGACCCTCACATAGAAATGATACCTGGAGCACACAG
  TATTCCCAGTGGACATGTGTATTCACTGTCCGAACCTGAAATGGCAGCTCTTCGAGATTTTGTGGCAAGA
  AATGTAAAAGATGGGCTAATTACTCCAACGATTGCACCTAATGGAGCCCAAGTTCTCCAGGTGAAGAGGG
  GGTGGAAACTGCAAGTTTCTTATGATTGCCGAGCTCCAAACAATTTTACTATCCAGAATCAGTATCCTCG
  CCTATCTATTCCAAATTTAGAAGACCAAGCACACCTGGCAACGTACACTGAATTCGTACCTCAAATACCT
  GGATACCAAACATACCCCACATATGCCGCGTACCCGACCTACCCAGTAGGATTCGCCTGGTACCCAGTGG
  GACGAGACGGACAAGGAAGATCACTATATGTACCTGTGATGATCACTTGGAATCCACACTGGTACCGCCA
  GCCTCCGGTACCACAGTACCCGCCGCCACAGCCGCCGCCTCCACCACCACCACCGCCGCCGCCTCCATCT
  TACAGTACCCTGTAAATACCTGTCATGTCCTTCAGGATCTCTGCCCTCAAAATTTATTCCTGTTCAGCTT
  CTCAATCAGTGACTGTGTGCTAAATTTTAGGCTACTGTATCTTCAGGCCACCTGAGGCACATCCTCTCTG
  AAACGGCTATGGAAGGTTAGGGCCACTCTGGACTGGCACACATCCTAAAGCACCAAAAGACCTTCAACAT
  TTTCTGAGAGCAACAGAGTATTTGCCAATAAATGATCTCTCATTTTTCCACCTTGACTGCCAATCTAACT
  AAAATAATTAATAAGTTTACTTTCCAGCCAGTCCTGGAAGTCTGGGTTTTACCTGCCAAAACCTCCATCA
  CCATCTAAATTATAGGCTGCCAAATTTGCTGTTTAACATTTACAGAGAAGCTGATACAAACGCAGGAAAT
  GCTGATTTCTTTATGGAGGGGGAGACGAGGAGGAGGAGGACATGACTTTTCTTGCGGTTTCGGTACCCTC
  TTTTTAAATCACTGGAGGACTGAGGCCTTATTAAGGAAGCCAAAATTATCGGTGCAGTGTGGAAAGGCTT
  CCGTGATCCTCTCGCTGCACCCTTAGAAACTTCACCGTCTTCAAACTCCATTTCCATGGTTCTGTTAATT
  CTCAAGGAGCAGCAACTCGACTGGTTCTCCCAGGAGCAGGAAAAACCCTTGTGACATGAAACATCTCAGG
  CCTGAAAAGAAAGTGCTCTCTCAGATGGACTCTTGCATGTTAAGACTATGTCTTCACATCATGGTGCAAA
  TCACATGTACCCAATGACTCCGGCTTTGACACAACACCTTACCATCATCATGCCATGATGGCTTCCACAA
  AGCATTAAACCTGGTAACCAGAGATTACTGGTGGCTCCAGCGTTGTTAGATGTTCATGAAATGTGACCAC
  CTCTCAATCACCTTTGAGGGCTAAAGAGTAGCACATCAAAAGGACTCCAAAATCCCATACCCAACTCTTA
  AGAGATTTGTCCTGGTACTTCAGAAAGAATTTTCATGAGTGTTCTTAATTGGCTGGAAAAGCACCAGCTG
  ACGTTTTGGAAGAATCTATCCATGTGTCTGCCTCCATATGCATCTGGGCATTTCATCTTCAGTCCCCTCA
  TTAGACTGTAGCATTAGGATGTGTGGAGAGAGGAGAAATGATTTAGCACCCAGATTCACACTCCTATGCC
  TGGAAGGGGGACATCTTTGAAGAAGAGGAATTAGGGCTGTGGACACTGTCTTGAGGATGTGGACTTCCTT
  AGTGAGCTCCACATTACTTGATGGTAACCACTTCAAAAGGATCAGAATCCACGTAATGAAAAAGGTCCCT
  CTAGAGGATGGAGCTGATGTGAAGCTGCCAATGGATGAAAAGCCTCAGAAAGCAACTCAAAGGACTCAAA
  GCAACGGACAACACAAGAGTTGTCTTCAGCCCAGTGACACCTCTGATGTCCCCTGGAAGCTTTGTGCTAA
  CCTGGGACTGCCTGACTTCCTTTAGCCTGGTCCCTTGCTACTACCTTGAACTGTTTTATCTAACCTCTCT
  TTTTCTGTTTAATTCTTTGCTACTGCCATTGACCCTGCTGCAGGATTTGTGTCATTTTCCTGCCTGGTTG
  CTGAGACTCCATTTTGCTGCCACACACAGAGATGTAAGAGGCAGGCTTTAATTGCCAAAGCACAGTTTGA
  GCAGTAGAAAACAACATGGTGTATATCTCAAATTGCCTGACATGAAGAGGAGTCTAACGGTGAAGTTTCA
  CTTTTCATCAGCATCATCTTTCACATGTTCATTATCATCTGCTCTTATTCTTGCATGTTTAAACACTTAA
  AATTTTTAGTATAATTTTTAGTGTGTTTTGAAGTGGTGACTAGGCTTTCAAAAACTTCCATTGAATTACA
  AAGCACTATCCAGTTCTTATTGTTAAACTAAGTAAAAATGATAAGTAACATAGTGTAAAATATTCCTTTA
  CTGTGAACTTCTTACAATGCTGTGAATGAGAGGCTCCTCAGAACTGGAGCATTTGTATAATAATTCATCC
  TGTTCATCTTCAATTTTAACATCATATATAATTTCAATTCTATCAATTGGGCCTTTAAAAATCATATAAA
  AGGATATAAAATTTGAAAAGAGAAACCTAATTGGCTATTTAATCCAAAACAACTTTTTTTTTCCTTCAAT
  GGAATCAGAAAGCTTGTCAATCACTCATGTGTTTTAGAGTAATTACTTTTAAAATGGTGCATTTGTGCTT
  CTGAACTATTTTGAAGAGTCACTTCTGTTTACCTCAAGTATCAATTCATCCTCCATACATTTGAATTCAA
  GTTGTTTTTTTGTCAAATTTACAGTTGTCAATTGATCTTCAAGCTGCAGGGTGCCTAGAAATGGGCCGTT
  GTCTGTAGCCCTGGCATGTGCACACGGACATTTGCCACCACTGCAAGCAAAAGTCTGGAGAAGTTCACCA
  ACGACAAGAACGATTAGGGAAAATATGCTGCTGTGGGTTAACAACTCAGAAAGTCCCTGATCCACATTTG
  GCTGTTTACTAAAGCTTGTGATTAACTTTTTGGCAGTGTGTACTATGCTCTATTGCTATATATGCTATCT
  ATAAATGTAGATGTTAAGGATAAGTAATTCTAAATTTATTATTCTATAGTTTTGAAGTTTGGTTAAGTTT
  CCTTTCACTCAATTGATTTATTTTGTTGTTAATCAAATTTATGTTAATTGGATCCTTTAAATTTTTTTTG
  GCATTTTCCAACAAAAATGGCTTTATTCATAAGAAAGGAAAAAAATCAATGGAATTTGATATCTAAAGAA
  GTTAGAAAGGGAGCAAAATAAAAAACATAAAGGAGATAGATGAATTAGTAAGCAAATCAGTAGTCGAGTT
  TTTCAAACTGGCAAAATTAATTAATTGACTTTTAGCCCAAATTTACATTGTTAATTAAATCAAGAAGGAA
  GAAGATCTAAGAGCTCCCATTGATAGGCAAGCCTAGAGAGAACTAGCTAAATTTATCATGCTAGGATATT
  GAAACACAGAAAGTTTACATACATTTATGAAGGGTCAATTTAGTTTGGACAGTGAGGTATTTGTCTTAGT
  GGAAAAAAGGAGAATTAGTCTGATCAAATCGTGAAGTAATACAGTGAACTTGCAGGTGCACAAAATAAGA
  GGGCCACATCTATATGGTGCAGTCTGGAATTCTGTTTAAGTTTGTAGGTACCTCTTGGACTTCTGAATTG
  ATCCAGTTGTCATCCACCACAGACATCTCACATCAGATACAGACAGTTCCAAGATTGACAACAGAGAACA
  ACCTGCTGGAAAGACCTGGGCAGAAATGGAGAGCCCTGCGGGAACCATGCTACATTTTCATCTAAAGAGA
  GAATGCACATCTGATGAGACTGAAAGTTCTTTGTTGTTTTAGATTGTAGAATGGTATTGAATTGGTCTGT
  GGAAAATTGCATTGCTTTTATTTCTTTGTGTAATCAAGTTTAAGTAATAGGGGATATATAATCATAAGCA
  TTTTAGGGTGGGAGGGACTATTAAGTAATTTTAAGTGGGTGGGGTTATTTAGAATGTTAGAATAATATTA
  TGTATTAGATATCGCTATAAGTGGACATGCGTACTTACTTGTAACCCTTTACCCTATAATTGCTATCCTT
  AAAGATTTCAAATAAACTCGGAGGGAACTGCAGGGAGACCAACTTATTTAGAGCGAATTGGACATGGATA
  AAAACCCCAGTGGGAGAAAGTTCAAAGGTGATTAGATTAATAATTTAATAGAGGATGAGTGACCTCTGAT
  AAATTACTGCTAGAATGAACTTGTCAATGATGGATGGTAAATTTTCATGGAAGTTATAAAAGTGATAAAT
  AAAAACCCTTGCTTTTACCCCTGTCAGTAGCCCTCCTCCTACCACTGAACCCCATTGCCCCTACCCCTCC
  TTCTAACTTTATTGCTGTATTCTCTTCACTCTATATTTCTCTCTATTTGCTAATATTGCATTGCTGTTAC
  AATAAAAATTCAATAAAGATTTAGTGGTTAAGTGCAAAAAAAAAAAAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015068 unedited
  TCCTCCCCCTCCCCCCAACAACAACAACAACAACAACTCCAAGCACACCGGCCATAAGAG
  TGCGTGTGTCCCCAACATGACCGAACGAAGAAGGGACGAGCTCTCTGAAGAGATCAACAA
  CTTAAGAGAGAAGGTCATGAAGCAGTCGGAGGAGAACAACAACCTGCAGAGCCAGGTGCA
  GAAGCTCACAGAGGAGAACACCACCCTTCGAGAGCAAGTGGAACCCACCCCTGAGGATGA
  GGATGATGACATCGAGCTCCGCGGTGCTGCAGCAGCTGCTGCCCCACCCCCTCCAATAGA
  GGAAGAGTGCCCAGAAGACCTCCCAGAGAAGTTCGATGGCAACCCAGACATGCTGGCTCC
  TTTCATGGCCCAGTGCCAGATCTTCATGGAAAAGAGCACCAGGGATTTCTCAGTTGATCG
  TGTCCGTGTCTGCTTCGTGACAAGCATGATGACCGGCCGTGCTGCCCGTTGGGCCTCAGC
  AAAGCTGGAGCGCTCCCACTACCTGATGCACAACTACCCAGCTTTCATGATGGAAATGAA
  GCATGTCTTTGAAGACCCTCAGAGGCGAGAGGTTGCCAAACGCAAGATCAGACGCCTGCG
  CCAAGGCATGGGGGTCTGTCATCGACTACTCCAATGCTTTCCAGATGATTGCCCAGGACC
  TGGATTGGAACGAGCCTGCGCTGATTGACCAGTACCACGAGGGCCTCAGCGACCACATTC
  AGGAGGAGCTCTNCCACCTCGAGGTCGNCAAGTCGCTGTCTGCTCTGATTGGGCAGTGCA
  TTCACATTGAGAGAAGGCTGGCCAGGGCTGCTGCAGCTCGCAGGCACGCTTCGCCCCCGG
  CGGCCTGGNNGTGCTACATGCAGCCCCCCCACCGGTAGATCAACGGAGCGGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015068 unedited
  ACTAAACGCCCTTGAGGTCGAGTTTTAATTCCTTTTTTTTTTTTTTTTTGCACTTAACCA
  CTAAATCTTTATTGAATTTTTATTGTAACAGCAATGCAATATTAGCAAATAGAGAGAAAT
  ATAGAGTGAAGAGAATACAGCAATAAAGTTAGAAGGAGGGGTAGGGGCAATGGGGTTCAG
  TGGTAGGAGGAGGGCTACTGACAGGGGTAAAAGCAAGGGTTTTTATTTATCACTTTTATA
  ACTTCCATGAAAATTTACCATCCATCATTGACAAGTTCATTCTAGCAGTAATTTATCAGA
  GGTCACTCATCCTCTATTAAATTATTAATCTAATCACCTTTGAACTTTCTCCCACTGGGG
  TTTTTATCCATGTCCAATTCGCTCTAAATAAGTTGGTCTCCCTGCAGTTCCCTCCGAGTT
  TATTTGAAATCTTTAAGGATAGCAATTATAGGGTAAAGGGTTACAAGTAAGTACGCATGT
  CCACTTATAGCGATATCTAATACATAATATTATTCTAACATTCTAAATAACCCCACCCAC
  TTAAAATTACTTAATAGTCCCTCCCACCCTACAATGCTTATGATTATATATTCCCCTATT
  ACTTAAACTTGATTACACAAAGAAATAAAAGCAATGCAATTTTTCACAGACCAATTTCAT
  ACCCTTCTACAATCTCAAACAACCAAGAACTTTCAGTCTTATCAGATGTGCATTCTCTTC
  TTAGATGAAAATGTACCATGGTTCCCCGCAGGGCTCTTCATTTCTGTTCACGGTCTTTTT
  CACACGGTGTTCTCTGTTGTCAATCTTGCACCTGTTCGTTTCTGATGGGAAATGCCTGGG
  GCGCATGACACCTGCTTCCATTCCGAGTCCAGCAGGGCCCTCCAACCTTCAACGAATTTC
  GAACTGCCATTAAAAAGTGGTCCCTTATTCTTGGCCCTGCAAGTCTCGGATTATTTCCGA
  TTGACACACAATTTCTTTTCTTTCATAAAAGACCCTCTTGTCAAATCAATGCCCTCTCAA
  TGAAGCAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015068
• ORF Size: 978 bp
• Insert Size: 6450
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015068.2, NP_055883.1
• RefSeq Size: 6628
• RefSeq ORF: 978
• Locus ID: 23089
• Gene Summary: This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis. Overexpression of this gene has been associated with several malignancies, such as hepatocellular carcinoma and B-cell lymphocytic leukemia. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. Additional isoforms resulting from alternatively spliced transcript variants, and use of upstream non-AUG (CUG) start codon have been reported for this gene. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) has two overlapping open reading frames (RF1 and RF2) and two in-frame translation initiation codons: an upstream non-AUG (CUG) and a downstream AUG. This isoform (1) is derived from RF1/RF2 by -1 translational frameshifting and use of downstream AUG start codon.