RBM5 (NM_005778) Human Untagged Clone

CAT#: SC108553

RBM5 (untagged)-Human RNA binding motif protein 5 (RBM5), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RBM5
• Synonyms: G15; H37; LUCA-15; LUCA15; RMB5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108553 sequence for NM_005778 edited (data generated by NextGen Sequencing)
  ATGGGTTCAGACAAAAGAGTGAGTAGAACAGAGCGTAGTGGAAGATACGGTTCCATCATA
  GACAGGGATGACCGTGATGAGCGTGAATCCCGAAGCAGGCGGAGGGACTCAGATTACAAA
  AGATCTAGTGATGATCGGAGGGGTGATAGATATGATGACTACCGAGACTATGACAGTCCA
  GAGAGAGAGCGTGAAAGAAGGAACAGTGACCGATCCGAAGATGGCTACCATTCAGATGGT
  GACTATGGTGAGCACGACTATAGGCATGACATCAGTGACGAGAGGGAGAGCAAGACCATC
  ATGCTGCGCGGCCTTCCCATCACCATCACAGAGAGCGATATTCGAGAAATGATGGAGTCC
  TTCGAAGGCCCTCAGCCTGCGGATGTGAGGCTGATGAAGAGGAAAACAGGTGTAAGCCGT
  GGTTTCGCCTTCGTGGAGTTTTATCACTTGCAAGATGCTACCAGCTGGATGGAAGCCAAT
  CAGAAAAAGTTGGTGATTCAAGGAAAGCACATTGCAATGCATTATAGCAATCCCAGACCT
  AAGTTTGAAGATTGGCTTTGTAACAAGTGCTGCCTTAACAATTTCAGGAAAAGACTAAAA
  TGCTTCCGATGTGGAGCAGACAAGTTTGACTCTGAACAGGAAGTGCCTCCTGGAACCACA
  GAGTCGGTTCAGTCTGTGGATTACTACTGTGATACGATCATTCTTCGGAACATAGCTCCG
  CACACTGTGGTGGATTCCATCATGACAGCACTGTCTCCTTACGCGTCTTTAGCTGTCAAT
  AACATCCGCCTCATAAAAGACAAACAGACCCAGCAGAACAGAGGCTTCGCATTTGTGCAG
  CTGTCCTCTGCAATGGATGCTTCTCAGCTGCTTCAGATATTACAGAGTCTCCATCCTCCT
  TTGAAAATTGATGGCAAAACTATTGGGGTTGATTTTGCAAAAAGTGCCAGAAAAGACTTG
  GTCCTCTCAGATGGTAACCGCGTCAGCGCCTTCTCTGTAGCTAGTACGGCTATTGCTGCT
  GCTCAGTGGTCATCCACCCAGTCTCAAAGTGGTGAAGGAGGCAGTGTTGACTACAGTTAT
  CTGCAACCAGGTCAAGATGGCTATGCCCAATATGCTCAGTATTCACAGGATTATCAGCAG
  TTTTATCAACAACAAGCTGGAGGATTGGAATCTGATGCATCATCTGCATCAGGCACAGCA
  GTGACCACCACCTCAGCGGCTGTAGTGTCCCAGAGTCCTCAGCTGTATAATCAAACCTCC
  AATCCACCTGGCTCTCCGACTGAGGAAGCACAGCCTAGCACTAGCACAAGTACACAGGCC
  CCAGCCGCTTCCCCTACTGGTGTAGTTCCTGGTACCAAATATGCAGTACCTGACACGTCC
  ACTTACCAGTATGATGAATCTTCAGGATATTACTATGATCCGACAACAGGGCTCTATTAT
  GACCCCAACTCGCAATACTACTATAATTCCTTGACCCAGCAGTACCTTTACTGGGATGGG
  GAAAAAGAGACCTACGTGCCAGCTGCAGAGTCTAGCTCCCACCAGCAGTCGGGCCTGCCT
  CCTGCAAAAGAGGGGAAAGAGAAGAAGGAGAAACCCAAGAGCAAAACAGCCCAGCAGATT
  GCCAAAGACATGGAACGCTGGGCTAAGAGTTTGAATAAGCAGAAAGAAAACTTTAAAAAT
  AGCTTTCAGCCTGTCAATTCCTTGAGGGAAGAAGAAAGGAGAGAATCTGCTGCAGCAGAC
  GCTGGCTTTGCTCTCTTTGAGAAGAAGGGAGCCTTAGCTGAAAGGCAGCAGCTCATCCCA
  GAATTGGTGCGAAATGGAGATGAGGAGAATCCCCTCAAAAGGGGTCTGGTTGCTGCTTAC
  AGTGGTGACAGTGACAATGAGGAGGAGCTGGTGGAGAGACTTGAGAGTGAGGAAGAGAAG
  CTAGCTGACTGGAAGAAGATGGCCTGTCTGCTCTGCCGGCGCCAGTTCCCGAACAAAGAT
  GCCCTAGTCAGGCACCAGCAACTCTCAGACCTTCACAAGCAAAACATGGACATCTACCGA
  CGATCCAGGCTGAGCGAGCAGGAGCTGGAAGCCTTGGAGCTAAGGGAGAGAGAGATGAAA
  TACCGAGACCGAGCTGCAGAAAGACGGGAGAAGTACGGCATTCCAGAACCTCCAGAGCCC
  AAGCGCAAGAAGCAGTTTGATGCCGGCACTGTGAATTACGAGCAACCCACCAAAGATGGC
  ATTGACCACAGTAACATTGGCAACAAGATGCTGCAGGCCATGGGCTGGCGGGAAGGCTCT
  GGCTTGGGACGAAAGTGTCAAGGCATTACGGCTCCCATTGAGGCTCAAGTTCGGCTAAAG
  GGAGCTGGCCTAGGAGCCAAAGGCAGCGCATATGGTTTGTCGGGCGCCGATTCCTACAAA
  GATGCTGTCCGGAAAGCCATGTTTGCCCGGTTCACTGAGATGGAGTGA
  
  Clone variation with respect to NM_005778.2
  990 t=>c;2037 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005778 unedited
  GGTCAAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGACGAGGCCTTGTTGGAG
  GTTCTGGGGCGCAGAACCGCTACTGCTGCTTCGGTCTCTCCTTGGNGAAAAAATAAAATT
  TGAACCTTTTGGAGCTGTGTGCTAAATCTTCAGTGGGACAATGGGTTCAGACAAAAGAGT
  GAGTAGAACAGAGCGTAGTGGAAGATACGGTTCCATCATAGACAGGGATGACCGTGATGA
  GCGTGAATCCCGAAGCAGGCGGAGGGACTCAGATTACAAAAGATCTAGTGATGATCGGAG
  GGGTGATAGATATGATGACTACCGAGACTATGACAGTCCAGAGAGAGAGCGTGAAAGAAG
  GAACAGTGACCGATCCGAAGATGGCTACCATTCAGATGGTGACTATGGTGAGCACGACTA
  TAGGCATGACATCAGTGACGAGAGGGAGAGCAAGACCATCATGCTGCGCGGCCTTCCCAT
  CACCATCACAGAGAGCGATATTCGAGAAATGATGGAGTCCTTCGAAGGCCCTCAGCCTGC
  GGATGTGAGGCTGATGAAGAGGAAAACAGGTGTAAGCCGTGGTTTCGCCTTCGTGGAGTT
  TTATCACTTGCAAGATGCTACCAGCTGGATGGAAGCCAATCAGAAAAAGTTGGTGATTCA
  AGGAAAGCACATTGCAATGCATTATAGCAATCCCAGACCTAAGTTTGAAGATTGGCTTTG
  TAACAAGTGCTGCCTTAACAATTTCAGGAAAGACTAAAATGCTTCCGATGTGGAGCAGAC
  CAGTTTGACTCTGAACAGAAAGTGCCTCCTGGGACCACGAGTCGGTCAGTCTGTGGATAC
  TACTGTGATCGAACTTTCTTCGAACTAACTCCGCCACTGTGGGGAATCCATCATGACAGA
  CTGTCTCTTACCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005778 unedited
  CTACAGGCTCATTTTNCTTCTCTGTTTAAGGGAGNCCAGNCATTTGGCAACTAGNACTGN
  AAAATCTTCCAAAATTCTGTACAAATGTGTAATATACAAATATACACAAGGCTTTTGCCA
  AGAAAAGACATCACAACAAATGACAGAGGTGGCTTTGGTGTCACATACCACCTACAGCAT
  CTCAAACCCCTAGGAATGTGAGGGGCTGATGGACCACAACATAGGCTACACATGTAAACA
  CGCTACATTACACTATGTACACTGGAGTATAAACAATCCACTGTCCTCTCCGGTCTGTTC
  ACAAGCCCTCTGGCGGGAAGGAAGGCCATTCACCAGGCAACCCACATAAGGGGAACTTCT
  TTAAGGTGGGAGGGAGAACCCTGCAGAATGAAGTGGTTCACCCTAAGATCTATTAACAGC
  ACAAGGCATGCCCTTAAAGAGACAGGCGGTAACAGCGAATTCGGGAGATGGACCACTTCT
  TGTGCTCCTTGTCATCTCTCTCTCTCTCTCTCTCTCACTCCATCTCAGTGAACCGGGCAA
  ACATGGCTTTCCGGACAGCATCTTTGTAGGAATCGGCGCCCGACAAACCATATGCGCTGC
  CTTTGGCTCCTAGGCCAGCTCCCTTTAGCCGAACTTGAGCCTCAATGGGAGCCGTAATGC
  CTTGACACTTTCGTCCCAAGCCAGAGCCTTTCCGCCAGCCCATGGCCTGCAGCATCTTGT
  TGCCAATGTTACTGTGGTCAATGCCATCTTTGGTGGCTGGCTCCGTAATTACAGTGCCCG
  CATAAACTGCTTCTTGCCCCTGGGCTCTGGAGGTTCTGGAATGCCGTACCTTTTCCCCCT
  TTCTTGCAGCTTGGGCCTNGGGATTTAATCTCCTTCTCCCTTACCTCCCAGGTTTCCATT
  CCTTGCTTGTCTAACCTGGATACTCCGCCAAAGTCCCTTGTTTGCTTTTGAAGGTCTAAA
  AATTCTTGCGCCCGACTAGGGCATTTTTTCTTGGAACTGCGCCCGCCTACACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005778
• ORF Size: 2448 bp
• Insert Size: 3100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005778.1, NP_005769.1
• RefSeq Size: 3135
• RefSeq ORF: 2448
• Locus ID: 10181
• Domains: G-patch, RRM, zf-RanBP, zf-C2H2
• Protein Families: Druggable Genome
• Gene Summary: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (1) represents the longer transcript and is protein coding.