Smad Interacting Protein 1 (ZEB2) (NM_014795) Human Untagged Clone

CAT#: SC108801

ZEB2 (untagged)-Human zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZEB2
• Synonyms: HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108801 sequence for NM_014795 edited (data generated by NextGen Sequencing)
  ATGAAGCAGCCGATCATGGCGGATGGCCCCCGGTGCAAGAGGCGCAAACAAGCCAATCCC
  AGGAGGAAAAACGTGGTGAACTATGACAATGTAGTGGACACAGGTTCTGAAACAGATGAG
  GAAGACAAGCTTCATATTGCTGAGGATGACGGTATTGCCAACCCTCTGGACCAGGAGACG
  AGTCCAGCTAGTGTGCCCAACCATGAGTCCTCCCCACACGTGAGCCAAGCTCTGTTGCCA
  AGAGAGGAAGAGGAAGATGAAATAAGGGAGGGTGGAGTGGAACACCCCTGGCACAACAAC
  GAGATTCTACAAGCCTCTGTAGATGGTCCAGAAGAAATGAAGGAAGACTATGACACTATG
  GGGCCAGAAGCCACGATCCAGACCGCAATTAACAATGGTACAGTGAAGAATGCAAATTGC
  ACATCAGATTTTGAGGAATACTTTGCCAAAAGAAAACTGGAGGAACGCGATGGTCATGCA
  GTCAGCATCGAGGAGTACCTTCAGCGCAGTGACACAGCCATTATTTACCCAGAAGCCCCT
  GAGGAGCTGTCTCGCCTTGGCACGCCAGAGGCCAATGGGCAAGAAGAAAATGACCTGCCA
  CCTGGAACTCCAGATGCTTTTGCCCAACTGCTGACCTGCCCCTACTGCGACCGGGGCTAC
  AAGCGCTTGACATCACTGAAGGAGCACATCAAGTACCGCCACGAGAAGAATGAAGAGAAC
  TTTTCCTGCCCTCTCTGTAGCTACACGTTTGCCTACCGCACCCAGCTCGAGCGGCATATG
  GTGACACACAAGCCAGGGACAGATCAGCACCAAATGCTAACCCAAGGAGCAGGTAATCGC
  AAGTTCAAATGCACAGAGTGTGGCAAGGCCTTCAAATATAAACACCATCTGAAAGAACAC
  CTGCGAATTCACAGTGGTGAAAAACCTTACGAGTGCCCAAACTGCAAGAAACGTTTCTCC
  CATTCTGGTTCCTACAGTTCGCACATCAGCAGCAAGAAATGTATTGGTTTAATCTCTGTA
  AATGGCCGAATGAGAAACAATATCAAGACGGGTTCTTCCCCTAATTCTGTTTCTTCTTCT
  CCTACTAATTCAGCCATTACCCAGTTAAGAAACAAGTTGGAGAATGGAAAACCACTTAGT
  ATGTCTGAACAGACAGGCTTACTTAAAATTAAAACAGAACCACTAGACTTCAATGACTAT
  AAAGTTCTTATGGCTACACACGGGTTTAGTGGCACTAGTCCCTTTATGAATGGTGGGCTT
  GGAGCCACCAGCCCTTTAGGAGTTCATCCATCTGCTCAGAGTCCAATGCAGCACTTAGGT
  GTAGGGATGGAAGCCCCTTTACTTGGGTTTCCCACCATGAATAGTAATTTAAGTGAGGTA
  CAAAAGGTTCTACAGATTGTGGACAATACTGTTTCCAGGCAAAAAATGGACTGCAAGGCT
  GAAGAAATTTCAAAGTTGAAAGGTTATCACATGAAGGATCCATGCTCTCAACCTGAGGAA
  CAAGGAGTTACTTCTCCTAATATTCCGCCTGTCGGTCTTCCGGTAGTGAGTCATAATGGT
  GCCACTAAAAGTATTATTGACTATACGTTGGAAAAAGTCAATGAAGCCAAAGCTTGCCTC
  CAGAGCTTGACTACTGACTCAAGGAGACAGATCAGTAATATAAAGAAAGAGAAGCTACGT
  ACTTTAATAGATTTGGTCACTGATGACAAAATGATTGAGAACCACAACATATCCACTCCA
  TTTTCATGCCAGTTCTGTAAAGAAAGTTTTCCTGGCCCCATCCCTTTGCATCAGCATGAA
  CGTTACCTTTGTAAGATGAATGAAGAGATCAAGGCGGTCCTGCAGCCTCATGAAAACATA
  GTCCCCAACAAAGCCGGAGTTTTTGTTGATAATAAAGCCCTCCTCTTGTCATCTGTACTT
  TCTGAGAAAGGAATGACAAGCCCCATCAACCCATACAAGGACCACATGTCTGTACTCAAA
  GCATACTATGCTATGAACATGGAGCCCAACTCCGATGAACTGCTGAAAATTTCCATTGCT
  GTGGGCCTTCCTCAGGAATTTGTGAAGGAATGGTTTGAACAACGAAAAGTCTACCAGTAC
  TCAAATTCCAGGTCCCCATCCCTGGAAAGAAGCTCCAAGCCGTTAGCTCCCAACAGTAAC
  CCTCCCACAAAAGACTCTTTATTACCCAGGTCTCCTGTAAAACCTATGGACTCCATAACA
  TCACCATCTATAGCAGAACTCCACAACAGTGTTACGAATTGTGATCCTCCTCTCAGGCTA
  ACAAAACCTTCCCATTTTACCAATATTAAACCAGTTGAAAAATTGGACCACTCCAGGAGT
  AATACTCCTTCTCCCTTAAATCTTTCCTCCACATCTTCTAAAAACTCCCACAGTAGTTCA
  TACACTCCAAACAGCTTCTCTTCTGAGGAGCTCCAGGCTGAGCCTTTAGACTTGTCATTA
  CCAAAACAAATGAAAGAACCCAAAAGTATTATAGCCACAAAGAACAAAACAAAAGCTAGT
  AGCATCAGTTTAGATCATAACAGTGTTTCTTCCTCATCTGAAAACTCAGATGAGCCTCTG
  AACTTGACTTTTATCAAGAAGGAATTTTCAAATTCAAATAATCTGGACAACAAAAGCACT
  AACCCAGTGTTCAGCATGAACCCATTTAGTGCCAAACCTTTATACACAGCTCTTCCACCT
  CAAAGCGCATTTCCCCCTGCTACTTTCATGCCACCAGTCCAGACCAGTATTCCTGGGCTA
  CGACCATACCCAGGACTGGATCAGATGAGCTTCCTACCACATATGGCCTACACCTACCCA
  ACTGGAGCAGCTACTTTTGCTGATATGCAGCAAAGGAGAAAGTACCAGCGGAAACAAGGA
  TTTCAGGGAGAATTGCTTGATGGAGCACAAGACTACATGTCAGGCCTAGATGATATGACA
  GACTCCGACTCCTGTCTGTCTCGCAAAAAGATCAAGAAGACAGAGAGTGGCATGTATGCA
  TGTGACTTATGTGACAAGACATTCCAGAAAAGCAGTTCCCTTCTGCGACATAAATACGAA
  CACACAGGAAAAAGACCACATCAGTGTCAGATTTGTAAGAAAGCGTTTAAACACAAGCAC
  CACCTTATCGAGCACTCAAGGCTTCACTCGGGCGAGAAGCCCTATCAGTGTGATAAATGT
  GGCAAGCGCTTCTCACACTCGGGCTCGTACTCGCAGCACATGAATCACAGGTATTCCTAC
  TGCAAGCGGGAGGCGGAGGAGCGGGAAGCGGCGGAGCGCGAGGCGCGCGAGAAAGGGCAC
  TTGGAACCCACCGAGCTGCTGATGAACCGGGCTTACTTGCAGAGCATTACCCCTCAGGGG
  TACTCTGACTCGGAGGAGAGGGAGAGTATGCCGAGGGATGGCGAGAGCGAGAAGGAGCAC
  GAGAAAGAAGGCGAGGATGGCTACGGGAAGCTGGGCAGACAGGATGGCGACGAGGAGTTC
  GAGGAGGAAGAGGAAGAAAGTGAAAATAAAAGTATGGATACGGATCCCGAAACGATACGA
  GATGAAGAAGAGACTGGAGATCACTCCATGGACGATAGTTCGGAGGATGGGAAAATGGAA
  ACCAAATCAGACCACGAGGAAGACAATATGGAAGATGGCATGTAA
  
  Clone variation with respect to NM_014795.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014795 unedited
  CAAATTTTGTATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGGTGGCGCGTG
  TTTCAGGGTCTCTCGTCTCTCTCCTACAGAAAAGAAAAAGAAAAAAATGTCATTAGAAGA
  GGCGTAACACGTCAGTCCGTCCCCAGGTTTGTGTTTCCTGGAGTGGCCGAAAGAGATCAG
  TTCTAACCTGCTCTGCAGGAATAACGGTCCTGCCTCCCGACACTCTTGGCGAGGTTTTTG
  TACAGTTTGCTCCGGGAGCTGTTTCTTCGCTTCCACCTTTTTCTCCCCCACACTTCGCGG
  CTTCTTCATGCTTTTTCTTCTCACCATTTCTGGCCAAAACTACAAACAAGACTTCGCAGA
  TCGAGCCTGCGTGCTGCCGAAGCAGGGCGCCGAGTCCATGCGAACTGCCATCTGATCCGC
  TCTTATCAATGAAGCAGCCGATCATGGCGGATGGCCCCCGGTGCAAGAGGCGCAAACAAG
  CCAATCCCAGGAGGAAAAACGTGGTGAACTATGACAATGTAGTGGACACAGGTTCTGAAA
  CAGATGAGGAAGACAAGCTTCATATTGCTGAGGATGACGGTATTGCCAACCCTCTGGACC
  AGGAGACGAGTCCAGCTAGTGTGCCCAACCATGAGTCCTCCCCACACGTGAGCCAAGCTC
  TGTTGCCAAGAGAGGAAGAGGAAGATGAAATAAGGGAGGGTGGAGTGGAACACCCCTGGC
  ACAANCACGAGAATTCTACAGCCTCTGTAGATGGTCCCAGAGAAATGAAGGAAGACTATG
  ACACTATGGNGCCCAGAGCCACGATCCAGAACCGCATTAACAATGGTACAGTGAAGAATG
  CANNATGCACATCAGATTTTGAGGGATACTTTGCCAAAGGAAACTGGGAGAACGCGATGG
  TCATGCAGTCAGCATCGAGGAGTACCTTCAGCGCAGTGACACAGCCATTATTTACCCAGA
  C
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014795 unedited
  NTTTAGCTTGGACCGGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTAGTTGGGCTACATTTTTATTCGAGCATGGGCATTTTCAA
  AAGAAATTACAAATTGAAAATTCAATAATACTTTTACAAAGACAATTCAGGAAAGATTTT
  TGGCATGGGATCATACATTGGATTTAACAGCCCCTTTTTTTAGCTAAAAAACAAGATGAA
  GAAAGGGGAATTTTCAGTCGAAAATACAGGGTTTTCACAAAATCGTATCAAAAGTTCCCA
  AATTTGGAATTTCCAGTAATTGGAAAAAAACAAAAATAAAATATTAAAATTGAAAAATCC
  CATCTCACAATTAATGTTCCAAAACACAATAAATGCTCTTCTTTTTACGTAAAATTTGCC
  CAAATGATCAACGGCATGTTCCTTTTTTACTAAAATATATCTATATATTGAAAAACTATA
  ATACTGGCCCCTACAGTATGAAATAAATAAAATTAGGAAATATAAAATGAGCCACATAAA
  TAAAATGTTATTTGACCTAAAATTAAATGAATGCAAAAAAAATTTTTTTGTTGCAAAAAC
  AGTTTGGGGTAATACTGCCAAAATTAATGAACAAAAAAGTCCAGAAAATAATTGCCCAAA
  CATATGTAAACTAAGGAACTGCTGCCTATTCTTCTAATACTGACATGGGTGCTTCAAAGA
  CAGGGTGAGCTTACACTGAAGCTGGTGCAAGTAACCCATGTTCCCTTCTTAAACTGGACA
  GGGATGCACTTGCAGAAACCAGATTAAAGGGTTGCATTAAGGGTTTTAAAACCCCCTACA
  AGGCTTCTTTATTCCCACCTAACTTTTCCTCCACGCCGGGCCTTTTAGACTTGGTATCTT
  AATCACCCTGCCTCACTTAGTTCCTTCCAGAAAAAAAAAATGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014795
• ORF Size: 3645 bp
• Insert Size: 5480
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014795.2, NP_055610.1
• RefSeq Size: 5583
• RefSeq ORF: 3645
• Locus ID: 9839
• Domains: homeobox, zf-C2H2
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.