EDG2 (LPAR1) (NM_057159) Human Untagged Clone

CAT#: SC109187

LPAR1 (untagged)-Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 2


  "NM_057159" in other vectors (6)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol LPAR1
Synonyms edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC109187 sequence for NM_057159 edited (data generated by NextGen Sequencing)
ATGGCTGCCATCTCTACTTCCATCCCTGTAATTTCACAGCCCCAGTTCACAGCCATGAAT
GAACCACAGTGCTTCTACAACGAGTCCATTGCCTTCTTTTATAACCGAAGTGGAAAGCAT
CTTGCCACAGAATGGAACACAGTCAGCAAGCTGGTGATGGGACTTGGAATCACTGTTTGT
ATCTTCATCATGTTGGCCAACCTATTGGTCATGGTGGCAATCTATGTCAACCGCCGCTTC
CATTTTCCTATTTATTACCTAATGGCTAATCTGGCTGCTGCAGACTTCTTTGCTGGGTTG
GCCTACTTCTATCTCATGTTCAACACAGGACCCAATACTCGGAGACTGACTGTTAGCACA
TGGCTCCTTCGTCAGGGCCTCATTGACACCAGCCTGACGGCATCTGTGGCCAACTTACTG
GCTATTGCAATCGAGAGGCACATTACGGTTTTCCGCATGCAGCTCCACACACGGATGAGC
AACCGGCGGGTAGTGGTGGTCATTGTGGTCATCTGGACTATGGCCATCGTTATGGGTGCT
ATACCCAGTGTGGGCTGGAACTGTATCTGTGATATTGAAAATTGTTCCAACATGGCACCC
CTCTACAGTGACTCTTACTTAGTCTTCTGGGCCATTTTCAACTTGGTGACCTTTGTGGTA
ATGGTGGTTCTCTATGCTCACATCTTTGGCTATGTTCGCCAGAGGACTATGAGAATGTCT
CGGCATAGTTCTGGACCCCGGCGGAATCGGGATACCATGATGAGTCTTCTGAAGACTGTG
GTCATTGTGCTTGGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTA
GACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCT
GAATTCAACTCTGCCATGAACCCCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCC
ACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGC
TCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGAC
CACTCTGTGGTTTAG

Clone variation with respect to NM_057159.2
>OriGene 5' read for NM_057159 unedited
GCGTTAGGATTTTGTAATACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGCACA
CTGTCCCGCCGCGGACGGGCTTTGTGGTTGGGGGCGCGCGTGCGAGTGCCAGTGAGAGTG
TGGGTGCGCGCTGTGGGCCGCGGCGCGGGTGGGTGGCCGTGCGTTCTTGCGAGCCGGCCT
GCAGGAGGCGAGGCTCCCCTGGCCTCCCGCACCCAGCGGCGGACCGAGCCCCTGGAGGGA
AGTTGCCGCAGCCGCCCGGGCCGCCGGCCCTCCTGTCCCGCGCCAGGGAACAGCTCCTGC
CCAGGTCTGTGGGCACTCAGCATGGATTTCAGTCTCCCTGTGAGTGATGGGAAAGAACTA
ACAGAGGCTGCAAGGTTTTACTGAATCTATTCCATTAGTGACCTACTGGAACGTTCAAAG
AATAAAAATCTCACTTGCTCAGTGTTTTTGATACACAGTGACATTCAGTCTGAAGTGTCA
TCCTTGAAGGATAGAATAAATCAGCTGTCGTGTTCTCAGTGAAAAGTGGAAAGAAGTTTT
AAAGGATCTGCANAATAGAATTATGAGACAGAGGAAAGAAAGAAACAGACAATCTGATCT
CTATCTTCATCGGCCAGGTGGACGTCTGATTTATGAAGCTCCCCATCCACCTATCTGAGT
ACCTGACTTCTCAGGACTGACACCTACAGCATCAGGTACACAGCTTCTCCTAGCATGACT
TCGATCTGATCACGCAACAAGAAAATTTGTCTTCCCGTATTTTTGGGGCGTGTTCACCAC
CTACAACCACCGGAGCTGTCATGGGTTGCCATTTCTACTTCCATCCCTGTGATTTTCACA
GCCCCCGGTTCACAGCCATGAATGAAACCACATGCTTTTAAAACGAGTCCATTGCGCTCT
TTTTATAACCCAGTGGGAAGTATT
>OriGene 3' read for NM_057159 unedited
NNNTTTACACTTTGGAACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTT
GATTGAAAATGATTTATTAAAGTCCAATTAGTATGCTTTTCATTTCAAATAATCCATATA
GCCTCCAGAAAAATATGCACATGTGTAAAAGTCCACGTTCATTTCTTTCACTTCCAATAT
AAAGTATTCTGTATTTTGTATAAAGTACGTGCAAACACCTTTCTGCTAATCGGGTCCCCA
CATTCTTTTCACTACAGGTACTTTACAAGTCTGCCCTCTGCTCAAACACTAACCGTGCAC
TGACATCCTCCTTCCTAGACAGCCATTCATCTCCCGGACTTCTTTCTCTCAGACATCCTC
CTGACCTCCCCTGACCTGCTTCACCACTGTGTTACCTCACTGGTTACTTGTTACAGCAAA
CTGATGCAACTACTAGTCTACCTGGACAACATATTAAACAGGTATCACCTAATAGGGTGG
CAGCCTATCGGGGTGATTCCTGGCGAATACACAGTAACCAACCACATACTGACACACTCA
ACCCATTTGCTACAGATGGACCCACACTAATTGATATGACAATCCTTTATTCACTCGGCA
CATTTGGTTTCTTTGCATTTTCTTCCATTTTACATTGCAGGTGTGGCTACCAAGAGCTGG
ATAACGAGTCCCTCAAACAAAGTTTGGAATTGCGAGATAAATTGGGGTACCTTGATTCTT
GAGACAGTTGAATTCCTCTAGTTGATCTTGGTGTATTAAAAAGTCCCTCTCAACTGAAGT
GAACACTGCATTTCTTTTGGAAAAAAGTCAATTGACTGGCTTTTCCTTACAAATGCCCCC
CTTGCCGTACAAAGCCGGGAATCCCTTTTATGGAAGGGGTAATTCCAAGAAGACT
Restriction Sites NotI-NotI     
ACCN NM_057159
Insert Size 4000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_057159.2, NP_476500.1
RefSeq Size 3182 bp
RefSeq ORF 1095 bp
Locus ID 1902
Cytogenetics 9q31.3
Domains 7tm_1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Gap junction, Neuroactive ligand-receptor interaction
Gene Summary 'The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-26 encode the same protein.

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