IL1RAP (NM_002182) Human Untagged Clone

CAT#: SC109339

IL1RAP (untagged)-Human interleukin 1 receptor accessory protein (IL1RAP), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL1RAP
• Synonyms: C3orf13; IL-1RAcP; IL1R3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002182 edited
  GAATTCGGCACCAGCAGGTCTCCGGGGTCCGCTTTGGCCAGAGGCGCGGAAGGAAGCAGT
  GCCCGGCGACACTGCACCCATCCCGGCTGCTTTTGCTGCGCCCTCTCAGCTTCCCAAGAA
  AGGCATCGTCATGTGATCATCACCTAAGAACTAGAACATCAGCAGGCCCTAGAAGCCTCA
  CTCTTGCCCCTCCCTTTAATATCTCAAAGGATGACACTTCTGTGGTGTGTAGTGAGTCTC
  TACTTTTATGGAATCCTGCAAAGTGATGCCTCAGAACGCTGCGATGACTGGGGACTAGAC
  ACCATGAGGCAAATCCAAGTGTTTGAAGATGAGCCAGCTCGCATCAAGTGCCCACTCTTT
  GAACACTTCTTGAAATTCAACTACAGCACAGCCCATTCAGCTGGCCTTACTCTGATCTGG
  TATTGGACTAGGCAGGACCGGGACCTTGAGGAGCCAATTAACTTCCGCCTCCCCGAGAAC
  CGCATTAGTAAGGAGAAAGATGTGCTGTGGTTCCGGCCCACTCTCCTCAATGACACTGGC
  AACTATACCTGCATGTTAAGGAACACTACATATTGCAGCAAAGTTGCATTTCCCTTGGAA
  GTTGTTCAAAAAGACAGCTGTTTCAATTCCCCCATGAAACTCCCAGTGCATAAACTGTAT
  ATAGAATATGGCATTCAGAGGATCACTTGTCCAAATGTAGATGGATATTTTCCTTCCAGT
  GTCAAACCGACTATCACTTGGTATATGGGCTGTTATAAAATACAGAATTTTAATAATGTA
  ATACCCGAAGGTATGAACTTGAGTTTCCTCATTGCCTTAATTTCAAATAATGGAAATTAC
  ACATGTGTTGTTACATATCCAGAAAATGGACGTACGTTTCATCTCACCAGGACTCTGACT
  GTAAAGGTAGTAGGCTCTCCAAAAAATGCAGTGCCCCCTGTGATCCATTCACCTAATGAT
  CATGTGGTCTATGAGAAAGAACCAGGAGAGGAGCTACTCATTCCCTGTACGGTCTATTTT
  AGTTTTCTGATGGATTCTCGCAATGAGGTTTGGTGGACCATTGATGGAAAAAAACCTGAT
  GACATCACTATTGATGTCACCATTAACGAAAGTATAAGTCATAGTAGAACAGAAGATGAA
  ACAAGAACTCAGATTTTGAGCATCAAGAAAGTTACCTCTGAGGATCTCAAGCGCAGCTAT
  GTCTGTCATGCTAGAAGTGCCAAAGGCGAAGTTGCCAAAGCAGCCAAGGTGAAGCAGAAA
  GTGCCAGCTCCAAGATACACAGTGGAACTGGCTTGTGGTTTTGGAGCCACAGTCCTGCTA
  GTGGTGATTCTCATTGTTGTTTACCATGTTTACTGGCTAGAGATGGTCCTATTTTACCGG
  GCTCATTTTGGAACAGATGAAACCATTTTAGATGGAAAAGAGTATGATATTTATGTATCC
  TATGCAAGGAATGCGGAAGAAGAAGAATTTGTATTACTGACCCTCCGTGGAGTTTTGGAG
  AATGAATTTGGATACAAGCTGTGCATCTTTGACCGAGACAGTCTGCCTGGGGGAATTGTC
  ACAGATGAGACTTTGAGCTTCATTCAGAAAAGCAGACGCCTCCTGGTTGTTCTAAGCCCC
  AACTACGTGCTCCAGGGAACCCAAGCCCTCCTGGAGCTCAAGGCTGGCCTAGAAAATATG
  GCCTCTCGGGGCAACATCAACGTCATTTTAGTACAGTACAAAGCTGTGAAGGAAACGAAG
  GTGAAAGAGCTGAAGAGGGCTAAGACGGTGCTCACGGTCATTAAATGGAAAGGGGAAAAA
  TCCAAGTATCCACAGGGCAGGTTCTGGAAGCAGCTGCAGGTGGCCATGCCAGTGAAGAAA
  AGTCCCAGGCGGTCTAGCAGTGATGAGCAGGGCCTCTCGTATTCATCTTTGAAAAATGTA
  TGAAAGGAATAATGAAAAGGGTAAAAAGAACAAGGGGTGCTCCAGGAAGAAAGAGTCCCC
  CCAGTCTTCATTCGCAGTTTATGGTTTCATAGGCAAAAATAATGGTCTAAGCCTCCCAAT
  AGGGATAAATTTAGGGTGACTGTGTGGCTGACTATTCTGCTTCCTCAGGCAACACTAAAG
  TTTAGAAAGATATCATCAACGTTCTGTCACCAGTCTCTGATGCCACTATGTTCTTTGCAG
  GCAAAGACTTGTTCAATGCGAATTTCCCCTTCTACATTGTCTATCCCTGTTTTTATATGT
  CTCCATTCTTTTTAAAATCTTAACATATGGAGCAGCCTTTCCTATGAATTTAAATATGCC
  TTTAAAATAAGTCACTGTTGACAGGGTCATGAGTTTCCGAGTATAGTTTTCTTTTTATCT
  TATTTTTACTCGTCCGTTGAAAAGATAATCAAGGCCTACATTTTAGCTGAGGATAATGAA
  CTTTTTTCCTCATTCGGCTGTATAATACATAACCACAGCAAGACTGACATCCACTTAGGA
  TGATACAAAGCAGTGTAACTGAAAATGTTTCTTTTAATTGATTTAAAGGACTTGTCTTCT
  ATACCACCCTTGTCCTCATCTCAGGTAATTTATGAAATCTATGTAAACTTGAAAAATATT
  TCTTAATTTTTGTTTTTGCTCCAGTCAATTCCTGATTATCCACAGGTCAACCCACATTTT
  TTCATTCCTTCTCCCTATCTGCTTATATCGCATTGCTCATTTAGAGTTTGCAGGAGGCTC
  CATACTAGGTTCAGTCTGAAAGAAATCTCCTAATGGTGCTATAGAGAXXXXXXXXXXXXX
  XXXXXXXXXXXCTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002182 unedited
  GTGCGAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACCAGCAGGTCT
  CCGGGGTCCGCTTTGGCCAGAGGCGCGGAAGGAAGCAGTGCCCGGCGACACTGCACCCAT
  CCCGGCTGCTTTTGCTGCGCCCTCTCAGCTTCCCAAGAAAGGCATCGTCATGTGATCATC
  ACCTAAGAACTAGAACATCAGCAGGCCCTAGAAGCCTCACTCTTGCCCCTCCCTTTAATA
  TCTCAAAGGATGACACTTCTGTGGTGTGTAGTGAGTCTCTACTTTTATGGAATCCTGCAA
  AGTGATGCCTCAGAACGCTGCGATGACTGGGGACTAGACACCATGAGGCAAATCCAAGTG
  TTTGAAGATGAGCCAGCTCGCATCAAGTGCCCACTCTTTGAACACTTCTTGAAATTCAAC
  TACAGCACAGCCCATTCAGCTGGCCTTACTCTGATCTGGTATTGGACTAGGCAGGACCGG
  GACCTTGAGGAGCCAATTAACTTCCGCCTCCCCGAGAACCGCATTAGTAAGGAGAAAGAT
  GTGCTGTGGTTCCGGCCCACTCTCCTCAATGACACTGGCAACTATACCTGCATGTTAAGG
  AACACTACATATTGCAGCAAAGTTGCATTTCCCTTGGAAGTTGTTCAAAAAGACAGCTGT
  TTCAATTCCCCCATGAAACTCCCAGTGCATAAACTGTATATAGAATATGGCATTCAGAGG
  ATCACTTGTCCAAATGTAGATGGATATTTTCCTTCCAGTGTCAAACCGACTATCACTTGG
  TATATGNGGCTGTTATAAAATACAGAATTTTAATAATGGTATACCCCGAAGGTATGAACT
  TGAGGTTCCTCATTGCCTTAATTTCAAATAATGGAAAATACACATGTTGTTGGTACATAT
  CCCAGAAATGGACGTACGTTTCATCTCCACAGGACTCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002182
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002182.2, NP_002173.1
• RefSeq Size: 4726 bp
• RefSeq ORF: 1713 bp
• Locus ID: 3556
• Cytogenetics: 3q28
• Domains: TIR, ig, IG
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction
• Gene Summary: 'This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]'
  Transcript Variant: This variant (1) encodes the membrane-bound isoform (1).