ABCD4 (NM_020324) Human Untagged Clone

CAT#: SC109688

ABCD4 (untagged)-Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 3


Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ABCD4
Synonyms ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC109688 sequence for NM_020324 edited (data generated by NextGen Sequencing)
ATGGCCAGCAAGCTCATCATCTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTC
CAAAGCACAGGCTGGCTCGGGCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTG
GTGAACAAAACTTTGATGGGCCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAG
GGAGATTTTAGGTTCAAGCACATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTAC
AGAGCTGGGCATGTGGAGCACATGAGGACAGACCGCAGGCTGCAGAGACTCCTTCAGACC
CAGAGGGAGCTGATGTCCAAGGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTAT
CTGGGCAGCATCCTGAGTTATGTTGTCATCGCAATCCCCATTTTCAGCGGGGTCTATGGA
GACCTGAGTCCCGCAGAGCTTAGCACCCTGGTCAGCAAGAATGCCTTTGTGTGCATCTAC
CTCATCAGCTGCTTCACCCAGCTAATCGACCTGTCCACGACGCTCTCAGATGTGGCTGGC
TACACGCACAGAATTGGGCAGCTTCGGGAGACGCTTCTGGACATGTCCCTGAAGTCACAG
GACTGCGAGATCCTGGGCGAGAGCGAGTGGGGCTTGGACACACCCCCAGGGTGGCCAGCG
GCAGAGCCAGCAGACACAGCATTTCTCCTTGAGCGGGTCTCCATCTCTGCCCCCTCCTCT
GACAAACCCCTAATCAAGGATCTGAGCCTAAAGATCTCCGAGGGACAGAGCCTGCTCATC
ACAGGCAACACGGGCACTGGCAAGACCTCCTTGCTCCGGGTTCTAGGTGGCCTCTGGACG
AGTACACGGGGCTCAGTGCAGATGCTGACGGACTTTGGGCCCCATGGGGTGCTATTCCTG
CCACAAAAGCCATTCTTCACTGACGGGACCCTTCGGGAGCAGGTGATATATCCCCTGAAG
GAGGTCTACCCCGACTCAGGTTCTGCCGATGATGAGAGGATCTTGAGGTTCTTGGAATTG
GCAGGCCTGTCCAACTTGGTGGCAAGGACAGAGGGCCTGGACCAGCAGGTGGACTGGAAC
TGGTATGATGTTCTGTCCCCGGGGGAGATGCAACGGCTCTCCTTTGCCCGACTCTTCTAC
CTGCAGCCGAAGTACGCAGTGCTTGATGAAGCCACCAGTGCCCTGACAGAGGAAGTGGAG
AGCGAGCTCTATCGCATCGGCCAGCAGCTGGGGATGACGTTCATCAGTGTGGGACATCGG
CAGAGCCTTGAGAAGTTTCATTCCTTGGTTCTGAAACTCTGTGGAGGAGGAAGATGGGAG
CTGATGAGAATCAAAGTGGAATGA

Clone variation with respect to NM_020324.1
504 c=>a;1056 t=>c
>OriGene 5' read for NM_020324 unedited
NGGTTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCGGGGCC
CGCGCCCGGAGCTGGCGCCAGGCCCAGGTTAGATCTGCAATTTCTCCAGCGGTTCCTGCA
GATACTGAAGGTTTTGTTTCCTTCTTGGTCATCACAAAATGCCTTGATGTTCCTGACCCT
TTTGTGCCTGACCCTACTGGAGCAATTTGTGATCTACCAGGTTGGCCTGATCCCCAGTCA
GTACTATGGGGTCCTGGGAAACAAAGACTTGGAAGGGTTTAAGACTCTGACATTCCTGGC
TGTCATGCTCATTGTTCTGAACTCCACGCTGAAGAGCTTTGATCAGTTCACCTGCAACCT
GCTGTATGTGAGCTGGAGGAAGGACCTCACTGAGCACCTTCACCGCCTCTACTTCCGGGG
CCGTGCGTACTACACCCTCAACGTGCTGCGGGATGACATCGATAACCCGGACCAGCGCAT
CAGCCAGGACGTGGAGCGATTCTGCCGGCAGCTCAGCAGCATGGCCAGCAAGCTCATCAT
CTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTCCAAAGCACAGGCTGGCTCGG
GCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTGGTGAACAAAACTTTGATGGG
CCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAGGGAGATTTTAGGTTCAAGCA
CATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTACAGAGCTGGGCATGTGGAGCA
CATGANGACAGACCGCNAGCTGCAGAGACTCCTTCAGACCCAGAGGGAGCTGATGTCCAA
GGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTATCTGGGCAGCANCCTGAGTTA
CGTTGTCATCGCAATCCCT
>OriGene 3' read for NM_020324 unedited
CTATGGACCCGCGGCCGCAATCTAGGATCGAGTTNTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTCTTTTTTTTTAAAAAAAAACAAAAAGCTGGAATTCTTTTTAATGGTTAAC
TTTTCTTTGGAAAAAACTTATTAAAAAACTTAAATGGGCAGTTAAAGTTAAAAATCTATT
GCTGCACAATTTAACTGATTAAAAGATTTCCAGATCTCTTGACTCCAAAAGTCATTTTTT
TCATTTCTTACAAATCTCACACTTCCAAATTTCTCTTTACCAAACATGATCTGAAATCAT
TTGTAGGTAATCAGCACTTCAAGCATATGGAGGCTTTGGCTGAGGCACCAAAGTCCTGGG
AAACTGAACACTGGGAAATTCAGTGTCCCCCACAAAAACCTAAACCTGGGCTCAACCCAC
CACTGCTAGGGGTCCTGCACAGGACCCATGTGGCTCCTGCCCGGGATCTATGGGGCGAAC
CTGAGCTCGATCTTCGCTGTCAGTCCTCCTGGTCTCTCCTGAGGGCCGCCGACCCGCCAC
AGTGTGGCTCTCCTTCCAAAAGCCAGAGCTTCATTCCACTTTGATTCTTATCAGCTCCCA
TCTTCCTCCTCCCAGAGTTTCAGAACCAAGGAATGAAACTTCTCAAGGTTCTGCCGATTC
CCCCACTGATAACGTCATCCCCACCTGCTGGCCGATGCGATAGAGCTCGTCCTCACTTCC
TCTGCAAGGCACTGGTGCCTCATCAACCCCTGGCACTTCGGCTGAGGAAAAAGAGCGGGC
AAAGAAACCGCTGCATTTCCCCCGGGACAGACATTTTACAACTTCATCCACCGGCTGGCC
AGCCCTTGTCCTTGCCCCAAGTGGCAGGCTCGCAATCCAAAACTAAAACCTCTTATATTG
CAAACCTGATCGGGACCCCCCTTAGGGAATATACCCCCCCCAGGCCCCCACGG
Restriction Sites NotI-NotI     
ACCN NM_020324
Insert Size 2240 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_020324.1, NP_064720.1
RefSeq Size 2787 bp
RefSeq ORF 2787 bp
Locus ID 5826
Cytogenetics 14q24.3
Domains ABC_tran, AAA
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
Gene Summary 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]'
Transcript Variant: This variant (3), as well as variant 13, encodes isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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