ABCD4 (NM_020324) Human Untagged Clone

CAT#: SC109688

ABCD4 (untagged)-Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCD4
• Synonyms: ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109688 sequence for NM_020324 edited (data generated by NextGen Sequencing)
  ATGGCCAGCAAGCTCATCATCTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTC
  CAAAGCACAGGCTGGCTCGGGCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTG
  GTGAACAAAACTTTGATGGGCCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAG
  GGAGATTTTAGGTTCAAGCACATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTAC
  AGAGCTGGGCATGTGGAGCACATGAGGACAGACCGCAGGCTGCAGAGACTCCTTCAGACC
  CAGAGGGAGCTGATGTCCAAGGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTAT
  CTGGGCAGCATCCTGAGTTATGTTGTCATCGCAATCCCCATTTTCAGCGGGGTCTATGGA
  GACCTGAGTCCCGCAGAGCTTAGCACCCTGGTCAGCAAGAATGCCTTTGTGTGCATCTAC
  CTCATCAGCTGCTTCACCCAGCTAATCGACCTGTCCACGACGCTCTCAGATGTGGCTGGC
  TACACGCACAGAATTGGGCAGCTTCGGGAGACGCTTCTGGACATGTCCCTGAAGTCACAG
  GACTGCGAGATCCTGGGCGAGAGCGAGTGGGGCTTGGACACACCCCCAGGGTGGCCAGCG
  GCAGAGCCAGCAGACACAGCATTTCTCCTTGAGCGGGTCTCCATCTCTGCCCCCTCCTCT
  GACAAACCCCTAATCAAGGATCTGAGCCTAAAGATCTCCGAGGGACAGAGCCTGCTCATC
  ACAGGCAACACGGGCACTGGCAAGACCTCCTTGCTCCGGGTTCTAGGTGGCCTCTGGACG
  AGTACACGGGGCTCAGTGCAGATGCTGACGGACTTTGGGCCCCATGGGGTGCTATTCCTG
  CCACAAAAGCCATTCTTCACTGACGGGACCCTTCGGGAGCAGGTGATATATCCCCTGAAG
  GAGGTCTACCCCGACTCAGGTTCTGCCGATGATGAGAGGATCTTGAGGTTCTTGGAATTG
  GCAGGCCTGTCCAACTTGGTGGCAAGGACAGAGGGCCTGGACCAGCAGGTGGACTGGAAC
  TGGTATGATGTTCTGTCCCCGGGGGAGATGCAACGGCTCTCCTTTGCCCGACTCTTCTAC
  CTGCAGCCGAAGTACGCAGTGCTTGATGAAGCCACCAGTGCCCTGACAGAGGAAGTGGAG
  AGCGAGCTCTATCGCATCGGCCAGCAGCTGGGGATGACGTTCATCAGTGTGGGACATCGG
  CAGAGCCTTGAGAAGTTTCATTCCTTGGTTCTGAAACTCTGTGGAGGAGGAAGATGGGAG
  CTGATGAGAATCAAAGTGGAATGA
  
  Clone variation with respect to NM_020324.1
  504 c=>a;1056 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020324 unedited
  NGGTTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCGGGGCC
  CGCGCCCGGAGCTGGCGCCAGGCCCAGGTTAGATCTGCAATTTCTCCAGCGGTTCCTGCA
  GATACTGAAGGTTTTGTTTCCTTCTTGGTCATCACAAAATGCCTTGATGTTCCTGACCCT
  TTTGTGCCTGACCCTACTGGAGCAATTTGTGATCTACCAGGTTGGCCTGATCCCCAGTCA
  GTACTATGGGGTCCTGGGAAACAAAGACTTGGAAGGGTTTAAGACTCTGACATTCCTGGC
  TGTCATGCTCATTGTTCTGAACTCCACGCTGAAGAGCTTTGATCAGTTCACCTGCAACCT
  GCTGTATGTGAGCTGGAGGAAGGACCTCACTGAGCACCTTCACCGCCTCTACTTCCGGGG
  CCGTGCGTACTACACCCTCAACGTGCTGCGGGATGACATCGATAACCCGGACCAGCGCAT
  CAGCCAGGACGTGGAGCGATTCTGCCGGCAGCTCAGCAGCATGGCCAGCAAGCTCATCAT
  CTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTCCAAAGCACAGGCTGGCTCGG
  GCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTGGTGAACAAAACTTTGATGGG
  CCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAGGGAGATTTTAGGTTCAAGCA
  CATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTACAGAGCTGGGCATGTGGAGCA
  CATGANGACAGACCGCNAGCTGCAGAGACTCCTTCAGACCCAGAGGGAGCTGATGTCCAA
  GGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTATCTGGGCAGCANCCTGAGTTA
  CGTTGTCATCGCAATCCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020324 unedited
  CTATGGACCCGCGGCCGCAATCTAGGATCGAGTTNTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTCTTTTTTTTTAAAAAAAAACAAAAAGCTGGAATTCTTTTTAATGGTTAAC
  TTTTCTTTGGAAAAAACTTATTAAAAAACTTAAATGGGCAGTTAAAGTTAAAAATCTATT
  GCTGCACAATTTAACTGATTAAAAGATTTCCAGATCTCTTGACTCCAAAAGTCATTTTTT
  TCATTTCTTACAAATCTCACACTTCCAAATTTCTCTTTACCAAACATGATCTGAAATCAT
  TTGTAGGTAATCAGCACTTCAAGCATATGGAGGCTTTGGCTGAGGCACCAAAGTCCTGGG
  AAACTGAACACTGGGAAATTCAGTGTCCCCCACAAAAACCTAAACCTGGGCTCAACCCAC
  CACTGCTAGGGGTCCTGCACAGGACCCATGTGGCTCCTGCCCGGGATCTATGGGGCGAAC
  CTGAGCTCGATCTTCGCTGTCAGTCCTCCTGGTCTCTCCTGAGGGCCGCCGACCCGCCAC
  AGTGTGGCTCTCCTTCCAAAAGCCAGAGCTTCATTCCACTTTGATTCTTATCAGCTCCCA
  TCTTCCTCCTCCCAGAGTTTCAGAACCAAGGAATGAAACTTCTCAAGGTTCTGCCGATTC
  CCCCACTGATAACGTCATCCCCACCTGCTGGCCGATGCGATAGAGCTCGTCCTCACTTCC
  TCTGCAAGGCACTGGTGCCTCATCAACCCCTGGCACTTCGGCTGAGGAAAAAGAGCGGGC
  AAAGAAACCGCTGCATTTCCCCCGGGACAGACATTTTACAACTTCATCCACCGGCTGGCC
  AGCCCTTGTCCTTGCCCCAAGTGGCAGGCTCGCAATCCAAAACTAAAACCTCTTATATTG
  CAAACCTGATCGGGACCCCCCTTAGGGAATATACCCCCCCCAGGCCCCCACGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020324
• Insert Size: 2240 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020324.1, NP_064720.1
• RefSeq Size: 2787 bp
• RefSeq ORF: 2787 bp
• Locus ID: 5826
• Cytogenetics: 14q24.3
• Domains: ABC_tran, AAA
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]'
  Transcript Variant: This variant (3), as well as variant 13, encodes isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.