PPAP2C (PLPP2) (NM_003712) Human Untagged Clone

CAT#: SC109963

PPAP2C (untagged)-Human phosphatidic acid phosphatase type 2C (PPAP2C), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLPP2
• Synonyms: LPP2; PAP-2c; PAP2-g; PPAP2C
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003712 edited
  GAATTCGGCACGAGGGGACCATGCAGCGGAGGTGGGTCTTCGTGCTGCTCGACGTGCTGT
  GCTTACTGGTCGCCTCCCTGCCCTTCGCTATCCTGACGCTGGTGAACGCCCCGTACAAGC
  GAGGATTTTACTGCGGGGATGACTCCATCCGGTACCCCTACCGTCCAGATACCATCACCC
  ACGGGCTCATGGCTGGGGTCACCATCACGGCCACCGTCATCCTTGTCTCGGCCGGGGAAG
  CCTACCTGGTGTACACAGACCGGCTCTATTCTCGCTCGGACTTCAACAACTACGTGGCTG
  CTGTATACAAGGTGCTGGGGACCTTCCTGTTTGGGGCTGCCGTGAGCCAGTCTCTGACAG
  ACCTGGCCAAGTACATGATTGGGCGTCTGAGGCCCAACTTCCTAGCCGTCTGCGACCCCG
  ACTGGAGCCGGGTCAACTGCTCGGTCTATGTGCAGCTGGAGAAGGTGTGCAGGGGAAACC
  CTGCTGATGTCACCGAGGCCAGGTTGTCTTTCTACTCGGGACACTCTTCCTTTGGGATGT
  ACTGCATGGTGTTCTTGGTGCTGTATGTGCAGGCACGACTCTGTTGGAAGTGGGCACGGC
  TGCTGCGACCCACAGTCCAGTTCTTCCTGGTGGCCTTTGCCCTCTACGTGGGCTACACCC
  GCGTGTCTGATTACAAACACCACTGGAGCGATGTCCTTGTTGGCCTCCTGCAGGGGGCAC
  TGGTGGCTGCCCTCACTGTCTGCTACATCTCAGACTTCTTCAAAGCCCGACCCCCACAGC
  ACTGTCTGAAGGAGGAGGAGCTGGAACGGAAGCCCAGCCTGTCACTGACGTTGACCCTGG
  GCGAGGCTGACCACAACCACTATGGATACCCGCACTCCTCCTCCTGAGGCCGGACCCCGC
  CCAGGCAGGGAGCTGCTGTGAGTCCAGCTGAGGCCCACCCAGGTGGTCCCTCCAGCCCTG
  GTTAGGCACTGAGGGCTCTGGACGGGCTCCAGGAACCCTGGGCTGATGGGAGCAGTGAGC
  GGGCTCCGCTGCCCCCTGCCCTGCACTGGACCAGGAGTCTGGAGATGCCTGGGTGGCCCT
  CAGCATTTGGAGGGGAACCTGTTCCCGTCGGTCCCCAAATATCCCCTTCTTTTTATGGGG
  TTAAGGAAGGGACCGAGAGATCAGATAGTTGCTGTTTTGTAAAATGTAATGTATATGTGG
  TTTTTAGTAAAATAGGGCACCTGTTTCACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003712 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGACCATGCAGCGGAG
  GTGGGTCTTCGTGCTGCTCGACGTGCTGTGCTTACTGGTCGCCTCCCTGCCCTTCGCTAT
  CCTGACGCTGGTGAACGCCCCGTACAAGCGAGGATTTTACTGCGGGGATGACTCCATCCG
  GTACCCCTACCGTCCAGATACCATCACCCACGGGCTCATGGCTGGGGTCACCATCACGGC
  CACCGTCATCCTTGTCTCGGCCGGGGAAGCCTACCTGGTGTACACAGACCGGCTCTATTC
  TCGCTCGGACTTCAACAACTACGTGGCTGCTGTATACAAGGTGCTGGGGACCTTCCTGTT
  TGGGGCTGCCGTGAGCCAGTCTCTGACAGACCTGGCCAAGTACATGATTGGGCGTCTGAG
  GCCCAACTTCCTAGCCGTCTGCGACCCCGACTGGAGCCGGGTCAACTGCTCGGTCTATGT
  GCAGCTGGAGAAGGTGTGCAGGGGAAACCCTGCTGATGTCACCGAGGCCAGGTTGTCTTT
  CTACTCGGGACACTCTTCCTTTGGGATGTACTGCATGGTGTTCTTGGTGCTGTATGTGCA
  GGCACGACTCTGTTGGAAGTGGGCACGGCTGCTGCGACCCACAGTCCAGTTCTTCCTGGT
  GGCCTTTGCCCTCTACGTGGGCTACCCCCGCGTGTCTGATTACAAACACCACTGGAGCGA
  TGTCCTTTGGTGGCCTCCTGGCAGGGGGCACTGGGTGGCTGCCCTCACTGTCTGCTACAT
  CTCAAACTTTCTTCAAAGCCCGACCCCACAGCACTGTCTTGAAGGGAGGAGGAGCTGGNA
  CGGNAAGCCCACCTGTCACTGACGGTGACCCTGGGCGAGGCTGACCACAACACTATTGAT
  ACCCGCACTNCTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003712 unedited
  TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTGAAACAGGTGCCC
  TATTTTACTAAAAACCACATATACATTACATTTTACAAAACAGCAACTATCTGATCTCTC
  GGTCCCTTCCTTAACCCCATAAAAAGAAGGGGATATTTGGGGACCGACGGGAACAGGTTC
  CCCTCCAAATGCTGAGGGCCACCCAGGCATCTCCAGACTCCTGGTCCAGTGCAGGGCAGG
  GGGCAGCGGAGCCCGCTCACTGCTCCCATCAGCCCAGGGTTCCTGGAGCCCGTCCAGAGC
  CCTCAGTGCCTAACCAGGGCTGGAGGGACCACCTGGGTGGGCCTCAGCTGGACTCACAGC
  AGCTCCCTGCCTGGGCGGGGTCCGGCCTCAGGAGGAGGAGTGCGGGTATCCATAGTGGTT
  GTGGTCAGCCTCGCCCAGGGTCAACGTCAGTGACAGGCTGGGCTTCCGTTCCAGCTCCTC
  CTCCTTCAGACAGTGCTGTGGGGGTCGGGCTTTGAAGAAGTCTGAGATGTAGCAGACAGT
  GAGGGCAGCCACCAGTGCCCCCTGCAGGAGGCCAACAAGGACATCGCTCCAGTGGTGTTT
  GTAATCAGACACGCGGGTGTAGCCCACGTAGAGGGCAAAGGCCACCAGGAAGAACTGGAC
  TGTGGGTCGCAGCAGCCGTGCCCACTTCCAACAGAGTCGTGCCTGCACATACAGCACCAA
  GAACACCATGCAGTACATCCCAAAGGAAGAGTGTCCCGAGTATAAAGACAACCTGGCCTC
  GGTGACATCAGCAGGGTTNTCCTTGCACACCTTCTTCAGCTGCACATAGACCGACCAGTT
  GACCCGCCTTCAATCCGGGTCGCAAACAGCTAGAAAGNTTGGCCTCAAACCCCAATCATG
  TACTGTGCCAGGTCTGTCAAAAACTGCTTACGGAAGCCCAAAAGAAAGGTCCCAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003712
• ORF Size: 867 bp
• Insert Size: 1260
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003712.2, NP_003703.1
• RefSeq Size: 1327
• RefSeq ORF: 867
• Locus ID: 8612
• Domains: acidPPc
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane
• Protein Pathways: Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism
• Gene Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' region, including the 5' UTR and 5' coding region, as compared to variant 3. The resulting isoform (1) has a distinct and shorter N-terminus, as compared to isoform 3.