PPAP2C (PLPP2) (NM_003712) Human Untagged Clone

CAT#: SC320713

PPAP2C (untagged)-Human phosphatidic acid phosphatase type 2C (PPAP2C), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLPP2
• Synonyms: LPP2; PAP-2c; PAP2-g; PPAP2C
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003712.2 CCGGGACGCGACGGGACGCGCTGGGACCGGCGTCGGGGGTCGCGGGGACCATGCAGCGGA
  GGTGGGTCTTCGTGCTGCTCGACGTGCTGTGCTTACTGGTCGCCTCCCTGCCCTTCGCTA
  TCCTGACGCTGGTGAACGCCCCGTACAAGCGAGGATTTTACTGCGGGGATGACTCCATCC
  GGTACCCCTACCGTCCAGATACCATCACCCACGGGCTCATGGCTGGGGTCACCATCACGG
  CCACCGTCATCCTTGTCTCGGCCGGGGAAGCCTACCTGGTGTACACAGACCGGCTCTATT
  CTCGCTCGGACTTCAACAACTACGTGGCTGCTGTATACAAGGTGCTGGGGACCTTCCTGT
  TTGGGGCTGCCGTGAGCCAGTCTCTGACAGACCTGGCCAAGTACATGATTGGGCGTCTGA
  GGCCCAACTTCCTAGCCGTCTGCGACCCCGACTGGAGCCGGGTCAACTGCTCGGTCTATG
  TGCAGCTGGAGAAGGTGTGCAGGGGAAACCCTGCTGATGTCACCGAGGCCAGGTTGTCTT
  TCTACTCGGGACACTCTTCCTTTGGGATGTACTGCATGGTGTTCTTGGCGCTGTATGTGC
  AGGCACGACTCTGTTGGAAGTGGGCACGGCTGCTGCGACCCACAGTCCAGTTCTTCCTGG
  TGGCCTTTGCCCTCTACGTGGGCTACACCCGCGTGTCTGATTACAAACACCACTGGAGCG
  ATGTCCTTGTTGGCCTCCTGCAGGGGGCACTGGTGGCTGCCCTCACTGTCTGCTACATCT
  CAGACTTCTTCAAAGCCCGACCCCCACAGCACTGTCTGAAGGAGGAGGAGCTGGAACGGA
  AGCCCAGCCTGTCACTGACGTTGACCCTGGGCGAGGCTGACCACAACCACTATGGATACC
  CGCACTCCTCCTCCTGAGGCCGGACCCCGCCCAGGCAGGGAGCTACTGTGAGTCCAGCTG
  AGGCCCACCCAGGTGGTCCCTCCAGCCCTGGTTAGGCACTGAGGGCTCTGGACGGGCTCC
  AGGAACCCTGGGCTGATGGGAGCAGTGAGCGGGCTCCGCTGCCCCCTGCCCTGCACTGGA
  CCAGGAGTCTGGAGATGCCTGGGTAGCCCTCAGCATTTGGAGGGGAACCTGTTCCCGTCG
  GTCCCCAAATATCCCCTTCTTTTTATGGGGTTAAGGAAGGGACCGAGAGATCAGATAGTT
  GCTGTTTTGTAAAATGTAATGTATATGTGGTTTTTAGTAAAATAGGGCACCTGTTTCAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003712.2 unedited
  GCCCATTGTATACGACTCCTATAGGGCGGGGGGGAATCGGCACGCAGGCCGGGACGCGAC
  GGGACGCGCTGGGACCGGCGTCGGGGGTCGCGGGGACCATGCAGCGGAGGTGGGTCTTCG
  TGCTGCTCGACGTGCTGTGCTTACTGGTCGCCTCCCTGCCCTTCGCTATCCTGACGCTGG
  TGAACGCCCCGTACAAGCGAGGATTTTACTGCGGGGATGACTCCATCCGGTACCCCTACC
  GTCCAGATACCATCACCCACGGGCTCATGGCTGGGGTCACCATCACGGCCACCGTCATCC
  TTGTCTCGGCCGGGGAAGCCTACCTGGTGTTCACAGACCGGCTCTATTCTCGCTCGGACT
  TCAACAACTACGTGGCTGCTGTATACAAGGTGCTGGGGACCTTCCTGTTTGGGGCTGCCG
  TGAGCCAGTCTCTGACAGACCTGGCCAAGTACATGATTGGGCGTCTGAGGCCCAACTTCC
  TAGCCGTCTGCGACCCCGACTGGAGCCGGGTCAACTGCTCGGTCTATGTGCAGCTGGAGA
  AGGTGTGCAGGGGAAACCCTGCTGATGTCACCGAGGCCAGGTTGTCTTTCTACTCGGGAC
  ACTCTTCCCTTTGGGATGTACTGCATGGTGTTCTTGGCGCTGTATGTGCAGGCACGACTC
  TGTTTGGAAGTGGGCACGGCTGCTGCGACCCACAGTCCAGTTCTTCCCTGGTGGCCTTTT
  GCCCTTCTACGTTGGGCTACCCCCCGCGTTGTCTGATTTACCAAACACCCACTGAAACGA
  TGTCCTTTGTTTGGCCCTCCTGCAGGGGGCACTTGGTGGGCTGGCCGTGACGTGCTGCTA
  CGTTTCAAAACTTTTTCAATACTCGAACCCCCACCACAACTGCTCTAAACGAGAAGTAGC
  CTGGAAGGAGAAGCCAAACCTGTACTGACGTTGAACCTGGCGAAGGCTTGACCAACACAC
  TATGGAATACCCCGAACTCATCTCTCTCTGAGAGGCGTG
• Restriction Sites: Please inquire
• ACCN: NM_003712
• ORF Size: 867 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003712.2, NP_003703.1
• RefSeq Size: 1327
• RefSeq ORF: 867
• Locus ID: 8612
• Domains: acidPPc
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane
• Protein Pathways: Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism
• Gene Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' region, including the 5' UTR and 5' coding region, as compared to variant 3. The resulting isoform (1) has a distinct and shorter N-terminus, as compared to isoform 3.