ARHGEF7 (NM_145735) Human Untagged Clone

CAT#: SC110008

ARHGEF7 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 7 (ARHGEF7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGEF7
• Synonyms: BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_145735, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCGCCCAAAAAAACCA
  TCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGATGGGGTGGTCCTCTGCAGGCTGCTGGAGCG
  CCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAGCCCCGGAGCGAGAGCGAGTGCCTGAGCAACATC
  CGCGAGTTCCTGCGCGGCTGCGGGGCTTCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGG
  GGCAGAATTTTAACAAGGTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGG
  GAGTGACTCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAGTCT
  TTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGAGTTTGGACATGACCGATAATAGCAACA
  ATCAACTGGTAGTAAGAGCAAAGTTTAACTTCCAGCAGACCAATGAGGACGAGCTTTCCTTCTCAAAAGG
  AGACGTCATCCATGTCACCCGTGTGGAAGAGGGAGGCTGGTGGGAGGGCACACTCAACGGCCGGACCGGC
  TGGTTCCCCAGCAACTACGTGCGCGAGGTCAAGGCCAGCGAGAAGCCTGTGTCTCCCAAATCAGGAACAC
  TGAAGAGCCCTCCCAAAGGATTTGATACGACTGCCATAAACAAAAGCTATTACAATGTGGTGCTACAGAA
  TATTTTAGAAACAGAAAATGAATATTCTAAAGAACTTCAGACTGTGCTTTCAACGTACCTACGGCCATTG
  CAGACCAGTGAGAAGTTAAGTTCAGCAAACATTTCATATTTAATGGGAAATCTAGAAGAAATATGTTCTT
  TCCAGCAAATGCTCGTACAGTCTTTAGAAGAATGCACCAAGTTGCCCGAAGCTCAGCAGAGAGTCGGAGG
  CTGCTTTTTAAACCTGATGCCACAGATGAAAACCCTGTACCTCACGTATTGTGCCAATCACCCTTCTGCA
  GTGAATGTCCTCACGGAACACAGTGAGGAGTTGGGGGAGTTCATGGAGACCAAAGGTGCCAGCAGCCCTG
  GGATTCTCGTGCTGACCACGGGCCTGAGCAAACCCTTCATGCGCCTGGATAAATACCCTACGCTGCTCAA
  AGAGCTCGAGAGACACATGGAGGATTATCATACAGATAGACAAGATATTCAAAAATCCATGGCTGCCTTC
  AAAAACCTTTCAGCCCAATGTCAAGAAGTCCGGAAGAGGAAAGAGCTTGAGCTGCAGATCCTGACGGAAG
  CCATCCGGAACTGGGAGGGCGATGACATTAAAACTCTGGGCAACGTCACTTACATGTCCCAGGTCCTGAT
  TCAGTGTGCCGGAAGTGAGGAAAAGAATGAAAGATATCTTCTACTCTTCCCAAATGTTTTGCTAATGTTG
  TCTGCCAGTCCTAGGATGAGTGGCTTTATCTATCAGGGAAAGCTTCCAACGACAGGAATGACAATCACAA
  AGCTTGAGGACAGTGAAAATCATAGAAATGCATTTGAAATATCAGGGAGCATGATTGAGCGGATATTAGT
  GTCGTGCAACAACCAGCAGGATCTGCAGGAATGGGTGGAGCACCTACAGAAGCAAACGAAGGTCACGTCT
  GTGGGAAACCCCACCATAAAGCCTCATTCAGTGCCATCTCATACCCTCCCCTCCCACCCGGTCACTCCGT
  CCAGCAAGCACGCAGACAGCAAGCCCGCGCCGCTGACGCCCGCCTACCACACGCTGCCCCACCCCTCCCA
  CCACGGCACCCCGCACACCACCATCAACTGGGGACCCCTGGAGCCTCCGAAAACACCCAAGCCCTGGAGC
  CTGAGCTGCCTGCGGCCCGCGCCTCCCCTCCGGCCCTCAGCTGCTCTCTGCTACAAGGAGGATCTTAGTA
  AGAGCCCTAAGACCATGAAAAAGCTGCTGCCCAAGCGCAAACCTGAACGGAAGCCTTCAGATGAGGAGTT
  CGCGTCCCGGAAAAGCACAGCTGCTTTGGAAGAAGATGCTCAGATTCTGAAAGTCATTGAAGCTTACTGC
  ACCAGCGCCAAAACAAGGCAAACACTCAATTCAACATGGCAAGGCACTGACCTGATGCATAATCACGTCT
  TGGCTGATGATGACCAACCAAGCCTAGACTCCCTGGGGCGTCGCAGTAGCCTTTCTCGTTTGGAGCCTTC
  AGACCTCTCGGAAGACTCTGACTATGACAGTATATGGACAGCCCATAGTTACAGAATGGGTTCTACATCT
  CGTAAGAGCTGTTGCTCATATATCTCTCACCAGAACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145735 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGNAGCCGCTCCTGAGAAGCGCCTG
  ACAGCGGGCCGGGGCGCACGGAGAAGCGGGCCGGGCCGGACCTGCTGGGCCGCGCCGAGC
  CAATCGCCGGCGCCGGCCGCTCGATGGGCGAGGCGGCGGCGGCGGCGGCGGGGGCCGCGG
  GCCGGGCCGCCGCTCCGAGGTGAAGGCGCGCGCCCCTCCCCGCCTGCCTCCCGGGCCGCA
  GCGATGAATTCCGCCGAGCAAACCGTTACGTGGCTCATCACTCTGGGGGTGCTGGAGTCG
  CCCAAAAAAACCATCTCGGACCCGGAGGGCTTTCTGCAGGCGTCGCTGAAGGATGGGGTG
  GTCCTCTGCAGGCTGCTGGAGCGCCTGCTCCCCGGGACCATCGAGAAAGTCTACCCCGAG
  CCCCGGAGCGAGAGCGAGTGCCTGAGCAACATCCGCGAGTTCCTGCGCGGCTGCGGGGCT
  TCCCTGCGGCTGGAGACGTTTGATGCAAATGATTTGTATCAGGGGCAGAATTTTAACAAG
  GTCCTCAGTTCCTTAGTGACTCTAAATAAAGTAACAGCAGACATCGGGCTGGGGAGTGAC
  TCCGTGTGTGCCCGGCCCTCGTCTCACCGCATAAAGTCTTTTGACTCCCTTGGATCACAG
  TCTTTGCACACTCGGACTTCAAAACTGTTCCAGGGCCAGTATCGGNAGTTTGGACATGAC
  CGANNTATAGCACAATCAACTGGTAGTAAGAGCCAAAGTTAACTTCCAGCAGACCAAGGG
  AGACGAGCNTTTCCTTCTCAAAAGGAGACGTCATCCATGTCACCCGTGTTGAANAAGGNA
  GCTGGTTGGNAGGCACACTCACGGGNCGGACCGGGTGGTTCCCCNCAACTACGTGCGCAA
  GGTCAGGCCANCGAAAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_145735 unedited
  CAGCTATGGACCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAATAAC
  GAGCCCATGGCAACCTAGTAATTCTTCAATGAACTTCAATATCCCATTACAATGAGGCAT
  TGCGGTTTTATACTATGGGGTTGCTGTAAATGGAGTTTCACTGCAGCTGGTTGCTGAAAA
  TAATGATGTGTCCATGGCTCTTCCAGACAACATAAGTATGGATGTCAGGGGTGGGGAGCC
  GCTGGATCTGAAGCCACAGCACTTGACTTTGTAAGTACTCCAAATGCCTCTACTACAGCC
  CAGTAGTCTACACTTGCAAAGGCTGAATGCTTTATCTTTCGGGCTTTAAACTGTTAATGT
  ATACATCTTACTGTAGACCCTTACAGGATCGCTCTGTGCCTCATCCCAGAATTCACTTGC
  CTTTCATGCCATTTCGGATTGCCTACCCCCGCCCACCCCCGACCCCTCGTACACCAGCCC
  TGACTTTCGAAAGCACACCTTACCTCTCCCCGGCCACCCCCCAACACTCTCACCACCTCC
  CCCCCGTAAGGTCCACGCTAGTTGGTTACAAACCCTCACGTACCCCCTCCCGCCCCACTG
  CTCCAGCTTCGCCCCCACCCCCGCTCCCCCCCCCCCCCGGCACAAGCGCGTGCATTTGGC
  TTTCTCACAATCCCGCCCGCCGTCTCCCTCCCCCCCCCTCCCCCCTCCCCCATATCTCCG
  TTTCCCCACCTCTACCACATCAGTTCCCATTTCTCTATCGCCCCCGCCGCCCATCAACAC
  ACCCCCCTTCTCCACCCTCCCCTTTCGAGGCGACCAAAACAATACTTAAAACGCCCCCTC
  CCCCCGCCCCTCTTCCCCACTTCTCATCCGCCAAGGTCGCCACCCCCTCCCCCCTCTCCC
  CTCATACCCCCCTCCCCCTCCCGCCCCCCCCATATTCCCCTTCTTGCCCTCACCCACTCT
  CGTACACGCCCGCCTCCGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_145735
• ORF Size: 2349 bp
• Insert Size: 3890
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_145735.1, NP_663788.1
• RefSeq Size: 5304
• RefSeq ORF: 2349
• Locus ID: 8874
• Domains: RhoGEF, SH3, CH, PH
• Protein Pathways: Regulation of actin cytoskeleton
• Gene Summary: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 3. The resulting protein (isoform b) is shorter than isoform c.